Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase

Biochimie

Volumn 102, Issue 1, 2014, Pages 117-123

  Kublun, Inga ^a   Ehm, Patrick ^a   Brehm, Maria A ^a   Nalaskowski, Marcus M ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Hydrogen peroxide; Import inhibition; Importazole; Inositol phosphate multikinase; Nuclear import

Indexed keywords

INOSITOL PHOSPHATE; INOSITOL PHOSPHATE MULTIKINASE; KARYOPHERIN ALPHA; KARYOPHERIN BETA; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; HYDROGEN PEROXIDE; IMPORTAZOLE; KARYOPHERIN; QUINAZOLINE DERIVATIVE;

ARTICLE; CELL GROWTH; CELL STRESS; CELLULAR DISTRIBUTION; CYTOPLASM; DRUG EFFECT; DRUG EFFICACY; EPIFLUORESCENCE MICROSCOPY; FLUORESCENCE MICROSCOPY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FUSION GENE; H1299 CELL LINE; HELA CELL LINE; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LUNG CANCER CELL LINE; LUNG NON SMALL CELL CANCER; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; SIGNAL TRANSDUCTION; TRANSIENT EXPRESSION; ACTIVE TRANSPORT; ANTAGONISTS AND INHIBITORS; CELL NUCLEUS; DRUG EFFECTS; GENETICS; METABOLISM;

ACTIVE TRANSPORT, CELL NUCLEUS; CELL NUCLEUS; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; INOSITOL PHOSPHATES; KARYOPHERINS; QUINAZOLINES; SIGNAL TRANSDUCTION;

EID: 84901765701     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2014.03.001     Document Type: Article

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