Dual targeted polymeric nanoparticles based on tumor endothelium and tumor cells for enhanced antitumor drug delivery

Molecular Pharmaceutics

Volumn 11, Issue 3, 2014, Pages 697-715

  Gupta, Madhu ^a   Chashoo, Gousia ^b   Sharma, Parduman Raj ^b   Saxena, Ajit Kumar ^b   Gupta, Prem Narayan ^b   Agrawal, Govind Prasad ^a   Vyas, Suresh Prasad ^a  

^a DR H S GOUR UNIVERSITY   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

CD13 receptor; cyclic NGR; docetaxel; nanoparticles; solid tumor

Indexed keywords

COPOLYMER; CYCLIC ASPARAGINYLGLYCYLARGININE PEPTIDE CONJUGATED POLY(ETHYLENE GLYCOL) POLY(ETHYLENE GLYCOL) BLOCK COPOLYMER; DOCETAXEL; LIGAND; MACROGOL; NANOCARRIER; POLYGLACTIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DRUG CARRIER; LACTIC ACID; MACROGOL DERIVATIVE; MICROSOMAL AMINOPEPTIDASE; NANOPARTICLE; NGR PEPTIDE; OLIGOPEPTIDE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER; TAXOID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG RETENTION; DRUG SOLUTION; DRUG SYNTHESIS; ENDOTHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; FOURIER TRANSFORM INFRARED PHOTOACOUSTIC SPECTROSCOPY; HEMOLYSIS; IN VITRO STUDY; IN VIVO STUDY; LIVER TOXICITY; MOUSE; NEPHROTOXICITY; NONHUMAN; PHAGOCYTOSIS; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCANNING ELECTRON MICROSCOPY; SURVIVAL TIME; SUSTAINED DRUG RELEASE; TEMPERATURE; TUMOR CELL; TUMOR VOLUME; UMBILICAL VEIN ENDOTHELIAL CELL; ZETA POTENTIAL; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; FIBROSARCOMA; FLOW CYTOMETRY; HUMAN; MACROPHAGE; METABOLISM; PATHOLOGY; TISSUE DISTRIBUTION;

ANIMALS; ANTIGENS, CD13; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CELLS, CULTURED; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FIBROSARCOMA; FLOW CYTOMETRY; HEMOLYSIS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LACTIC ACID; MACROPHAGES; MICE; MICE, INBRED BALB C; NANOPARTICLES; OLIGOPEPTIDES; PHAGOCYTOSIS; POLYETHYLENE GLYCOLS; POLYGLYCOLIC ACID; POLYMERS; TAXOIDS; TISSUE DISTRIBUTION;

EID: 84901740648     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp400404p     Document Type: Article

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