Expression of hippo pathway in colorectal cancer

Saudi Journal of Gastroenterology

Volumn 20, Issue 3, 2014, Pages 188-194

  Liang, Kun ^a   Zhou, Guangxi ^a   Zhang, Qi ^a   Li, Jing ^b   Zhang, Cuiping ^a  

^a QINGDAO UNIVERSITY   (China)

^b OCEAN UNIVERSITY OF CHINA   (China)

Author keywords

Colorectal adenomas; colorectal cancer; Hippo pathway; tumorigenesis

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LARGE TUMOR SUPPRESSOR 1; MAMMALIAN STE20 LIKE KINASE 1; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; TEA DOMAIN FAMILY MEMBER 1; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTIONAL CO ACTIVATOR WITH PDZ BINDING MOTIF; UNCLASSIFIED DRUG; YES ASSOCITATED PROTEIN; CDX2 PROTEIN, HUMAN; HIPPO PROTEIN, HUMAN; HOMEODOMAIN PROTEIN; LATS2 PROTEIN, HUMAN; MACROPHAGE STIMULATING PROTEIN; ONCOPROTEIN; POU5F1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SCATTER FACTOR; TUMOR SUPPRESSOR PROTEIN;

ADULT; ARTICLE; CANCER GROWTH; CANCER TISSUE; CLINICAL ARTICLE; COLORECTAL ADENOMA; COLORECTAL CANCER; CORRELATIONAL STUDY; DOWN REGULATION; FEMALE; HIPPO PATHWAY; HOUSEKEEPING GENE; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR DIFFERENTIATION; UPREGULATION; WESTERN BLOTTING; ADENOCARCINOMA; ADENOMA; AGED; ANALYSIS OF VARIANCE; APOPTOSIS; CANCER STAGING; CARCINOGENESIS; CELL PROLIFERATION; CELL TRANSFORMATION; COLORECTAL TUMOR; COMPARATIVE STUDY; EPIDEMIOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; TUMOR INVASION;

ADENOCARCINOMA; ADENOMA; ADULT; AGED; ANALYSIS OF VARIANCE; APOPTOSIS; BLOTTING, WESTERN; CARCINOGENESIS; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE GROWTH FACTOR; HOMEODOMAIN PROTEINS; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; OCTAMER TRANSCRIPTION FACTOR-3; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; SAMPLING STUDIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84901718450     PISSN: 13193767     EISSN: 19984049     Source Type: Journal    
DOI: 10.4103/1319-3767.133025     Document Type: Article

References (27)

1. Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010;127:2893-917
2. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012;62:10-29
3. Brenner H, Kloor M, Pox CP. Colorectal cancer. Lancet 2013
4. Prasetyanti PR, Zimberlin CD, Bots M, Vermeulen L, De Sousa EM, Medema JP. Regulation of stem cell self-renewal and differentiation by Wnt and Notch are conserved throughout the adenoma-carcinoma sequence in the colon. Mol Cancer 2013;12:126
5. Zhao B, Li L, Lei Q, Guan KL. The Hippo-YAP pathway in organ size control and tumorigenesis: An updated version. Genes Dev 2010;24:862-74
6. Takahashi Y, Miyoshi Y, Takahata C, Irahara N, Taguchi T, Tamaki Y, et al. Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers. Clin Cancer Res 2005;11:1380-5. (Pubitemid 40315216)
7. Sasaki H, Kawano O, Endo K, Suzuki E, Yukiue H, Kobayashi Y, et al. Human MOB1 expression in non-small-cell lung cancer. Clin Lung Cancer 2007;8:273-6. (Pubitemid 46333574)
8. Kowalik MA, Saliba C, Pibiri M, Perra A, Ledda-Columbano GM, Sarotto I, et al. Yes-Associated protein regulation of adaptive liver enlargement and hepatocellular carcinoma development in mice. Hepatology 2011;53:2086-96
9. Dong J, Feldmann G, Huang J, Wu S, Zhang N, Comerford SA, et al. Elucidation of a universal size-control mechanism in Drosophila and mammals. Cell 2007;130:1120-33. (Pubitemid 47410268)
10. Chan EH, Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, Sillje HH. The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1. Oncogene 2005;24:2076-86. (Pubitemid 40516201)
11. Zhou D, Conrad C, Xia F, Park JS, Payer B, Yin Y, et al. Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene. Cancer Cell 2009;16:425-38
12. Xu CM, Liu WW, Liu CJ, Wen C, Lu HF, Wan FS. Mst1 overexpression inhibited the growth of human non-small cell lung cancer in vitro and in vivo. Cancer Gene Ther 2013;20:453-60
13. Seidel C, Schagdarsurengin U, Blumke K, Wurl P, Pfeifer GP, Hauptmann S, et al. Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma. Mol Carcinog 2007;46:865-71. (Pubitemid 47549772)
14. Zhao B, Ye X, Yu J, Li L, Li W, Li S, et al. TEAD mediates YAP-dependent gene induction and growth control. Genes Dev 2008;22:1962-71. (Pubitemid 352008643)
15. Xu MZ, Yao TJ, Lee NP, Ng IO, Chan YT, Zender L, et al. Yes-Associated protein is an independent prognostic marker in hepatocellular carcinoma. Cancer 2009;115:4576-85
16. Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, et al. YAP1 increases organ size and expands undifferentiated progenitor cells. Curr Biol 2007;17:2054-60. (Pubitemid 350180465)
17. Zhou D, Zhang Y, Wu H, Barry E, Yin Y, Lawrence E, et al. Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-Associated protein overabundance. Proc Natl Acad Sci USA 2011;108:E1312-20
18. Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X. TAZ is a novel oncogene in non-small cell lung cancer. Oncogene 2011;30:2181-6
19. Yuen HF, McCrudden CM, Huang YH, Tham JM, Zhang X, Zeng Q, et al. TAZ expression as a prognostic indicator in colorectal cancer. PloS One 2013;8:e54211
20. Liu Y, Xin Y, Ye F, Wang W, Lu Q, Kaplan HJ, et al. Taz-tead1 links cell-cell contact to zeb1 expression, proliferation, and dedifferentiation in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2010;51:3372-8
21. Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R, et al. Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation. Cell 2005;123:917-29. (Pubitemid 41721036)
22. Silberg DG, Swain GP, Suh ER, Traber PG. Cdx1 and cdx2 expression during intestinal development. Gastroenterology 2000;119: 961-71
23. Mallo GV, Soubeyran P, Lissitzky JC, Andre F, Farnarier C, Marvaldi J, et al. Expression of the Cdx1 and Cdx2 homeotic genes leads to reduced malignancy in colon cancer-derived cells. J Biol Chem 1998;273:14030-6. (Pubitemid 28268460)
24. Kim SP, Park JW, Lee SH, Lim JH, Jang BC, Jang IH, et al. Homeodomain protein CDX2 regulates COX-2 expression in colorectal cancer. Biochem Biophys Res Commun 2004;315:93-9. (Pubitemid 38175190)
25. Hong KD, Lee D, Lee Y, Lee SI, Moon HY. Reduced CDX2 expression predicts poor overall survival in patients with colorectal cancer. Am Surg 2013;79:353-60
26. Nishioka N, Inoue K, Adachi K, Kiyonari H, Ota M, Ralston A, et al. The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Dev Cell 2009;16:398-410
27. Hay DC, Sutherland L, Clark J, Burdon T. Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 2004;22:225-35. (Pubitemid 38282637)