Heparan sulfate containing unsubstituted glucosamine residues: Biosynthesis and heparanase-inhibitory activity

Journal of Biological Chemistry

Volumn 289, Issue 22, 2014, Pages 15231-15243

  Nadanaka, Satomi ^a   Purunomo, Eko ^a   Takeda, Naoko ^b   Tamura, Jun Ichi ^b   Kitagawa, Hiroshi ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS;

CANCER CELLS; DEACETYLASE; HEPARAN SULFATES; HEPARANASE; IN-VITRO; INHIBITORY ACTIVITY; TETRASACCHARIDES; TUMOR METASTASIS;

SULFUR COMPOUNDS;

ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; EXOSTOSIN LIKE 3; GLUCOSAMINE; HEPARAN SULFATE; HEPARANASE; HEPARANASE INHIBITOR; N ACETYLGLUCOSAMINE; PROTEIN NDST 1; REGULATOR PROTEIN; SULFOTRANSFERASE; TETRASACCHARIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOSYNTHESIS; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CARBOHYDRATE ANALYSIS; CARBOHYDRATE METABOLISM; CARBOHYDRATE SYNTHESIS; CATALYSIS; CELL INVASION; CONTROLLED STUDY; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN MODIFICATION; REGULATORY MECHANISM; RESIDUE ANALYSIS; STRUCTURE ANALYSIS;

GLYCOBIOLOGY; GLYCOSAMINOGLYCAN; GLYCOSIDASE; HEPARAN SULFATE; HEPARANASE; PROTEOGLYCAN; PROTEOGLYCAN SYNTHESIS;

ANIMALS; BREAST NEOPLASMS; FEMALE; FIBROBLASTS; GLUCOSAMINE; GLUCURONIDASE; GLYCOSAMINOGLYCANS; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; MCF-7 CELLS; MICE; N-ACETYLGLUCOSAMINYLTRANSFERASES; NEOPLASM INVASIVENESS; SULFOTRANSFERASES;

EID: 84901708331     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.545343     Document Type: Article

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