EXTL2, a member of the EXT family of tumor suppressors, controls glycosaminoglycan biosynthesis in a xylose kinase-dependent manner

Journal of Biological Chemistry

Volumn 288, Issue 13, 2013, Pages 9321-9333

  Nadanaka, Satomi ^a   Zhou, Shaobo ^a   Kagiyama, Shoji ^a   Shoji, Naoko ^a   Sugahara, Kazuyuki ^a,c   Sugihara, Kazushi ^b   Asano, Masahide ^b   Kitagawa, Hiroshi ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL SIGNIFICANCE; CHAIN ELONGATION; CHONDROITIN SULFATES; GLYCOSAMINOGLYCANS; H NMR SPECTROSCOPY; PENTASACCHARIDES; TETRASACCHARIDES; TUMOR SUPPRESSORS;

BIOCHEMISTRY; ENZYMES; GENES; HYDROGELS; MAMMALS; OLIGOSACCHARIDES; PHOSPHORYLATION;

BIOSYNTHESIS;

CHONDROITIN SULFATE; EXOSTOSIN 2; GLYCOSAMINOGLYCAN; GLYCOSIDASE; HEPARAN SULFATE; N ACETYLGLUCOSAMINE; OLIGOSACCHARIDE; PHOSPHOTRANSFERASE; TETRASACCHARIDE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; XYLOSE KINASE 1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXOSTOSIN 2 GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; HELA CELL; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN CARBOHYDRATE INTERACTION; PROTEIN FUNCTION; PROTON NUCLEAR MAGNETIC RESONANCE; RNA TRANSLATION; STRUCTURE ANALYSIS; TUMOR SUPPRESSOR GENE;

ALLELES; ANIMALS; CLONING, MOLECULAR; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, TUMOR SUPPRESSOR; GENOMICS; GLYCOSAMINOGLYCANS; GLYCOSYLTRANSFERASES; HELA CELLS; HUMANS; LIVER; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; MUTATION; N-ACETYLGLUCOSAMINYLTRANSFERASES; PHOSPHOTRANSFERASES; PROTEOGLYCANS; RNA, MESSENGER; XYLOSE;

MUS;

EID: 84875969039     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.416909     Document Type: Article

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