Simple, low-cost molecular assays for TR34/L98H mutations in the cyp51A gene for rapid detection of triazole-resistant aspergillus fumigatus isolates

Journal of Clinical Microbiology

Volumn 52, Issue 6, 2014, Pages 2223-2227

  Ahmad, Suhail ^a   Khan, Ziauddin ^a   Hagen, Ferry ^b   Meis, Jacques F ^b,c  

^a KUWAIT UNIVERSITY   (Kuwait)

^b CANISIUS WILHELMINA HOSPITAL   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL DNA; ITRACONAZOLE; RIBOSOME DNA; TRIAZOLE; ANTIFUNGAL AGENT; CYTOCHROME P-450 CYP51A, ASPERGILLUS; CYTOCHROME P450; FUNGAL PROTEIN; TRIAZOLE DERIVATIVE;

ANTIFUNGAL RESISTANCE; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLUS FUMIGATUS; BROTH DILUTION; CODON; CONTROLLED STUDY; CYP51A GENE; FUNGAL DETECTION; FUNGAL GENE; FUNGAL STRAIN; FUNGUS ISOLATION; GENE AMPLIFICATION; GENE MUTATION; GENE TARGETING; GENETIC ANALYSIS; GENOME SIZE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; COST; DRUG EFFECTS; ECONOMICS; ENZYMOLOGY; GENETICS; GENOTYPING TECHNIQUE; HUMAN; MICROBIAL SENSITIVITY TEST; MISSENSE MUTATION; PROCEDURES;

ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; COSTS AND COST ANALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; FUNGAL PROTEINS; GENOTYPING TECHNIQUES; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TRIAZOLES;

EID: 84901684441     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00408-14     Document Type: Article

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