Dichloroacetate prevents restenosis in preclinical animal models of vessel injury

Nature

Volumn 509, Issue 7502, 2014, Pages 641-644

  Deuse, Tobias ^a,b   Hua, Xiaoqin ^a,b   Wang, Dong ^a,b   Maegdefessel, Lars ^c   Heeren, Joerg ^b   Scheja, Ludger ^b   Bolaños, Juan P ^d   Rakovic, Aleksandar ^e   Spin, Joshua M ^f   Stubbendorff, Mandy ^a,b   Ikeno, Fumiaki ^f   Länger, Florian ^g   Zeller, Tanja ^a,b   Schulte Uentrop, Leonie ^b   Stoehr, Andrea ^b   Itagaki, Ryo ^a,b   Haddad, Francois ^f   Eschenhagen, Thomas ^b   Blankenberg, Stefan ^a,b   Kiefmann, Rainer ^b   Reichenspurner, Hermann ^a,b   Velden, Joachim ^h   Klein, Christine ^e   Yeung, Alan ^f   Robbins, Robert C ⁱ   Tsao, Philip S ^f,j   Schrepfer, Sonja ^a,b,i   more..

^a UNIVERSITY HEART CENTER HAMBURG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

^d Instituto de Biología Funcional y Genómica and Departamento de Microbiología y Genética   (Spain)

^e UNIVERSITY OF LÜBECK   (Germany)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g HANNOVER MEDICAL SCHOOL   (Germany)

^h UNIVERSITY HOSPITAL ERLANGEN   (Germany)

ⁱ STANFORD UNIVERSITY   (United States)

^j VA PALO ALTO HEALTH CARE SYSTEM   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CD68 ANTIGEN; CYTOCHROME C; DICHLOROACETIC ACID; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE 1; PLATELET DERIVED GROWTH FACTOR; PYRUVATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE KINASE 2; SHORT HAIRPIN RNA;

ACETATE; ANIMAL; CELL ORGANELLE; INJURY; MITOCHONDRION; NUMERICAL MODEL; PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD VESSEL INJURY; CONTROLLED STUDY; CORONARY ARTERY; HUMAN; HUMAN TISSUE; ILIAC ARTERY; IN VITRO STUDY; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; NEUTROPHIL; NEW ZEALAND WHITE (RABBIT); NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; RESTENOSIS; SWINE;

ANIMALIA; ORYCTOLAGUS CUNICULUS; RATTUS; SUIDAE;

ANGIOPLASTY, BALLOON; ANIMALS; AORTA; APOPTOSIS; ARTERIES; CELL PROLIFERATION; CONSTRICTION, PATHOLOGIC; CORONARY VESSELS; DICHLOROACETIC ACID; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPERPLASIA; ILIAC ARTERY; MAMMARY ARTERIES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MYOCYTES, SMOOTH MUSCLE; PROTEIN-SERINE-THREONINE KINASES; RABBITS; RATS; RECURRENCE; STENTS; SWINE; TUNICA INTIMA;

EID: 84901670648     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13232     Document Type: Article

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