Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 21, 2014, Pages 7735-7740

  David, Alexandria ^a,b   Crawford, Frances ^a,b   Garside, Paul ^c   Kappler, John W ^a,b,d   Marrack, Philippa ^a,b,d   MacLeod, Megan ^c  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CASPASE; CD28 ANTIGEN; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR5; INTERLEUKIN 7 RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CELL SURVIVAL; DELAYED HYPERSENSITIVITY; ENZYME ACTIVATION; FLOW CYTOMETRY; IMMUNOLOGICAL MEMORY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS; AUTOIMMUNE DISEASES; CASPASES; CD4-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENES, MHC CLASS II; IMMUNE TOLERANCE; IMMUNOLOGIC MEMORY; IMMUNOTHERAPY; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL;

EID: 84901650260     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1406218111     Document Type: Article

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