Protective immunity induced with the RTS,S/AS vaccine is associated with IL-2 and TNF-α producing effector and central memory CD4 + T cells

PLoS ONE

Volumn 6, Issue 7, 2011, Pages

  Lumsden, Joanne M ^a   Schwenk, Robert J ^a   Rein, Lisa E ^a   Moris, Philippe ^b   Janssens, Michel ^b   Ofori Anyinam, Opokua ^b   Cohen, Joe ^b   Kester, Kent E ^a   Heppner, D Gray ^a   Krzych, Urszula ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCUMSPOROZOITE PROTEIN; GROWTH FACTOR; INTERLEUKIN 2; MALARIA VACCINE; SUBUNIT VACCINE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ANTIBODY TITER; ARTICLE; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; DOUBLE BLIND PROCEDURE; EFFECTOR CELL; HELPER CELL; HUMAN; HUMAN EXPERIMENT; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOSTIMULATION; IN VITRO STUDY; INFECTION PREVENTION; LYMPHOCYTE FUNCTION; MALARIA FALCIPARUM; MEMORY T LYMPHOCYTE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHASE 2 CLINICAL TRIAL; PLASMODIUM FALCIPARUM; RANDOMIZED CONTROLLED TRIAL; SPOROZOITE; T LYMPHOCYTE SUBPOPULATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOLOGY; MALE; METABOLISM;

PLASMODIUM FALCIPARUM;

CD4-POSITIVE T-LYMPHOCYTES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; INTERLEUKIN-2; MALARIA VACCINES; MALE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79960149284     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020775     Document Type: Article

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