Hyaluronate-gold nanoparticle/Tocilizumab complex for the treatment of rheumatoid arthritis

ACS Nano

Volumn 8, Issue 5, 2014, Pages 4790-4798

  Lee, Hwiwon ^a   Lee, Min Young ^a   Bhang, Suk Ho ^b   Kim, Byung Soo ^b   Kim, Yun Seop ^a   Ju, Ji Hyeon ^c   Kim, Ki Su ^d   Hahn, Sei Kwang ^a  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Seoul National University   (South Korea)

^c The Catholic University of Korea   (South Korea)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

drug delivery; gold nanoparticle; hyaluronic acid; rheumatoid arthritis; tocilizumab

Indexed keywords

CARTILAGE; DISEASES; DRUG DELIVERY; DRUG PRODUCTS; DYNAMIC LIGHT SCATTERING; GOLD; GOLD COMPOUNDS; TISSUE; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET VISIBLE SPECTROSCOPY;

ARTICULAR CARTILAGES; COLLAGEN-INDUCED ARTHRITIS; GOLD NANOPARTICLES; HUMANIZED MONOCLONAL ANTIBODY; IMMUNOSUPPRESSIVE DRUGS; RHEUMATOID ARTHRITIS; TOCILIZUMAB; WESTERN-BLOT ANALYSIS;

HYALURONIC ACID;

COLLAGEN; DITHIOTHREITOL; GOLD; HYALURONIC ACID; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 6; METAL NANOPARTICLE; MONOCLONAL ANTIBODY; TOCILIZUMAB;

ANIMAL; ARTHRITIS, RHEUMATOID; ARTICULAR CARTILAGE; CARTILAGE; CHEMISTRY; DBA MOUSE; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INFLAMMATION; LIGHT; MOUSE; NANOTECHNOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PROCEDURES; SYNOVIUM; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROPHOTOMETRY; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ARTHRITIS, RHEUMATOID; CARTILAGE; CARTILAGE, ARTICULAR; COLLAGEN; DITHIOTHREITOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GOLD; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYALURONIC ACID; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; INTERLEUKIN-6; LIGHT; MAGNETIC RESONANCE SPECTROSCOPY; METAL NANOPARTICLES; MICE; MICE, INBRED DBA; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTECHNOLOGY; SPECTROPHOTOMETRY, ULTRAVIOLET; SYNOVIAL MEMBRANE;

EID: 84901649576     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn500685h     Document Type: Article

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