Abnormalities of quantities and functions of natural killer cells in severe aplastic anemia

Immunological Investigations

Volumn 43, Issue 5, 2014, Pages 491-503

  Liu, Chunyan ^a   Li, Zhishang ^a   Sheng, Weiwei ^a   Fu, Rong ^a   Li, Lijuan ^a   Zhang, Tian ^a   Wu, Yuhong ^a   Xing, Limin ^a   Song, Jia ^a   Wang, Huaquan ^a   Shao, Zonghong ^a  

^a TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Aplastic anemia; NK lymphocyte; Perforin

Indexed keywords

CD56 ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NATURAL KILLER CELL RECEPTOR NKG2D; PERFORIN; GRANZYME; IMMUNOSUPPRESSIVE AGENT; KLRK1 PROTEIN, HUMAN; MESSENGER RNA; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY K; NCR1 PROTEIN, HUMAN;

ADULT; AGED; APLASTIC ANEMIA; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HEMATOPOIESIS; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE FUNCTION; MALE; NATURAL KILLER CELL; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEVERE APLASTIC ANEMIA; T LYMPHOCYTE; ADOLESCENT; ANEMIA, APLASTIC; BLOOD; CASE CONTROL STUDY; CHILD; CHROMOSOME ABERRATION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; LEUKOCYTE COUNT; METABOLISM; MIDDLE AGED; PHENOTYPE; PRESCHOOL CHILD; THROMBOCYTE COUNT; TREATMENT OUTCOME; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANEMIA, APLASTIC; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; FEMALE; GRANZYMES; HUMANS; IMMUNOPHENOTYPING; IMMUNOSUPPRESSIVE AGENTS; KILLER CELLS, NATURAL; LEUKOCYTE COUNT; MALE; MIDDLE AGED; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; PERFORIN; PHENOTYPE; PLATELET COUNT; RNA, MESSENGER; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84901629885     PISSN: 08820139     EISSN: 15324311     Source Type: Journal    
DOI: 10.3109/08820139.2014.888448     Document Type: Article

References (25)

1. Bacigalupo A. (2007). Aplastic anemia: Pathogenesis and treatment. Amer Soc Hematol Educ Prog Book, 1, 23-8.
2. Baje'noff M, Breart B, Huang AYC, et al. (2006). Natural killer cell behavior in lymph nodes revealed by static and real-Time imaging. J Exper Med, 203, 619-31.
3. Brillard E, Pallandre JR, Chalmers D, et al. (2007). Natural killer cells prevent CD28-mediated Foxp3 transcription in CD4+CD25-T lymphocytes. Exper Hematol, 35, 416-25.
4. Fan YY, Yang BY, Wu CY. (2008). Phenotypic and functional heterogeneity of natural killer cells from umbilical cord blood mononuclear cells. Immunol Invest, 37, 79-96.
5. Ferlazzo G, Morandi B, D'Agostino A, et al. (2003). The interaction between NK cells and dendritic cells in bacterial infections results in rapid induction of NK cell activation and in the lysis of uninfected dendritic cells. Euro J Immunol, 33, 306-13.
6. Hattori M, Terasawa T, Tsushita K, et al. (2008). The status of antithymocyte globulin therapy for adult patients in Japan: Retrospective analysis of a nationwide survey. Inter J Hematol, 87, 48-55.
7. Huntington ND, Vosshenrich CAJ, Di Santo JP. (2007). Developmental pathways that generate natural-killer-cell diversity in mice and humans. Nat Rev Immunol, 7, 703-14.
8. Kastrukoff LF, Lau A, Wee R, et al. (2003). Clinical relapses of multiple sclerosis are associated with 'novel'valleys in natural killer cell functional activity. J Neuroimmunol, 145, 103-14.
9. Lünemann A, Lünemann JD, Mü nz C. (2009). Regulatory NK-cell functions in inflammation and autoimmunity. Mol Med, 15, 352-8.
10. Marsh JCW, Ball SE, Cavenagh J, et al. (2009). Guidelines for the diagnosis and management of aplastic anaemia. Br J Haematol, 147, 43-70.
11. Nausch N, Cerwenka A. (2008). NKG2D ligands in tumor immunity. Oncogene, 27, 5944-58.
12. Nocentini G, Ronchetti S, Cuzzocrea S, et al. (2007). GITR/GITRL: More than an effector T cell co-stimulatory system. Euro J Immunol, 37, 1165-9.
13. Park MJ, Bae JH, Chung JS, et al. (2011). Induction of NKG2D ligands and increased sensitivity of tumor cells to NK cell-mediated cytotoxicity by hematoporphyrin-based photodynamic therapy. Immunol Invest, 40, 367-82.
14. Park YW, Kee SJ, Cho YN, et al. (2009). Impaired differentiation and cytotoxicity of natural killer cells in systemic lupus erythematosus. Arthritis Rheumat, 60, 1753-63.
15. Perona-Wright G, Mohrs K, Szaba FM, et al. (2009). Systemic but not local infections elicit immunosuppressive IL-10 production by natural killer cells. Cell Host Microbe, 6, 503-12.
16. Solomou E E, Gibellini F, Stewart B, et al. (2007a). Perforin gene mutations in patients with acquired aplastic anemia. Blood, 109, 5234-7.
17. Solomou EE, Keyvanfar K, Young NS. (2006). T-bet, a Th1 transcription factor, is upregulated in T cells from patients with aplastic anemia. Blood, 107, 398-1.
18. Solomou EE, Rezvani K, Mielke S, et al. (2007b). Deficient CD4+ CD25+ FOXP3+ T regulatory cells in acquired aplastic anemia. Blood, 110, 1603-6.
19. Svahn J, Dufour C, Ferretti E, et al. (2007). Further characterization of the cytokine profile in acquired aplastic anemia[C]. Haematol-Hematol J Strada Nuova Pavia, Italy: Ferrata Storti Foundation, 92, 27-8.
20. Wang H, Grzywacz B, Sukovich D, et al. (2007). The unexpected effect of cyclosporin A on CD56+ CD16-And CD56+ CD16+ natural killer cell subpopulations. Blood, 110, 1530-9.
21. Wang H, Zheng X, Wei H, et al. (2012). Important role for NKp30 in synapse formation and activation of NK cells. Immunol Invest, 41, 367-81.
22. Young NS, Scheinberg P, Calado RT. (2008). Aplastic anemia. Curr Opin Hematol, 15, 162-8.
23. Zhou R, Wei H, Tian Z. (2007). NK3-like NK cells are involved in protective effect of polyinosinic-polycytidylic acid on type 1 diabetes in nonobese diabetic mice. J Immunol, 178, 2141-7.
24. Zonghong S. (2007). The research of aplastic anemia. Basic Clin Med, 27, 233-7.
25. Zonghong S, Meifeng T, Huaquan W, et al. (2011). Circulating myeloid dendritic cells are increased in individuals with severe aplastic anemia. Inter J Hematol, 93, 156-62.