Reactive oxygen species generation is essential for cisplatininduced accelerated senescence in hepatocellular carcinoma

Frontiers of Medicine in China

Volumn 8, Issue 2, 2014, Pages 227-235

  Qu, Kai ^a   Lin, Ting ^a   Wang, Zhixin ^a   Liu, Sinan ^a   Chang, Hulin ^a   Xu, Xinsen ^a   Meng, Fandi ^a   Zhou, Lei ^a   Wei, Jichao ^a   Tai, Minghui ^a   Dong, Yafeng ^b   Liu, Chang ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

cisplatin; hepatocellular carcinoma; reactive oxygen species; senescence

Indexed keywords

ANTINEOPLASTIC AGENT; CDKN1A PROTEIN, HUMAN; CISPLATIN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 2A; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

CARCINOMA, HEPATOCELLULAR; CELL AGING; DRUG EFFECTS; FLOW CYTOMETRY; HEPG2 CELL LINE; HUMAN; LIVER NEOPLASMS; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL AGING; CELL LINE, TUMOR; CISPLATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FLOW CYTOMETRY; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; REACTIVE OXYGEN SPECIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84901612821     PISSN: 16737342     EISSN: 16737458     Source Type: Journal    
DOI: 10.1007/s11684-014-0327-1     Document Type: Article

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