Brief Report: Alternative activation of laser-captured murine hemophagocytes

Arthritis and Rheumatology

Volumn 66, Issue 6, 2014, Pages 1666-1671

  Canna, Scott W ^a   Costa Reis, Patrícia ^b   Bernal, William E ^c   Chu, Niansheng ^b   Sullivan, Kathleen E ^d   Paessler, Michele E ^d   Behrens, Edward M ^d  

^a NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CD163 ANTIGEN; CD206 ANTIGEN; CD64 ANTIGEN; INTERLEUKIN 10 RECEPTOR; RNA; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW BIOPSY; CELL FUNCTION; CELL ISOLATION; CONTROLLED STUDY; ERYTHROPHAGOCYTOSIS; HEMOPHAGOCYTE; HEMOPHAGOCYTIC SYNDROME; HUMAN; INFLAMMATION; LASER CAPTURE MICRODISSECTION; MACROPHAGE; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA EXTRACTION; UPREGULATION;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BONE MARROW CELLS; HUMANS; LASERS; LECTINS, C-TYPE; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MACROPHAGE ACTIVATION; MACROPHAGES; MANNOSE-BINDING LECTINS; MICE; MODELS, ANIMAL; RECEPTORS, CELL SURFACE; RECEPTORS, IGG; RECEPTORS, INTERLEUKIN-10; TOLL-LIKE RECEPTOR 9;

EID: 84901611447     PISSN: 23265191     EISSN: 23265205     Source Type: Journal    
DOI: 10.1002/art.38379     Document Type: Article

References (15)

1. Mosser DM, Edwards JP,. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008; 8: 958-69.
2. Canna SW, Behrens EM,. Not all hemophagocytes are created equally: appreciating the heterogeneity of the hemophagocytic syndromes. Curr Opin Rheumatol 2012; 24: 113-8.
3. Zoller EE, Lykens JE, Terrell CE, Aliberti J, Filipovich AH, Henson PM, et al. Hemophagocytosis causes a consumptive anemia of inflammation. J Exp Med 2011; 208: 1203-14.
4. Billiau AD, Roskams T, Van Damme-Lombaerts R, Matthys P, Wouters C,. Macrophage activation syndrome: characteristic findings on liver biopsy illustrating the key role of activated, IFN-γ-producing lymphocytes and IL-6- and TNF-α-producing macrophages. Blood 2005; 105: 1648-51.
5. Ohyagi H, Onai N, Sato T, Yotsumoto S, Liu J, Akiba H, et al. Monocyte-derived dendritic cells perform hemophagocytosis to fine-tune excessive immune responses. Immunity 2013; 39: 584-98.
6. Canna SW, Wrobel J, Chu N, Kreiger PA, Paessler M, Behrens EM,. Interferon-γ mediates anemia but is dispensable for fulminant Toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis in mice. Arthritis Rheum 2013; 65: 1764-75.
7. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003; 4: 249-64.
8. Huang DW, Sherman BT, Lempicki RA,. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 2009; 4: 44-57.
9. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A 2005; 102: 15545-50.
10. Coates PJ, Rundle JK, Lorimore SA, Wright EG,. Indirect macrophage responses to ionizing radiation: implications for genotype-dependent bystander signaling. Cancer Res 2008; 68: 450-6.
11. Schaer CA, Schoedon G, Imhof A, Kurrer MO, Schaer DJ,. Constitutive endocytosis of CD163 mediates hemoglobin-heme uptake and determines the noninflammatory and protective transcriptional response of macrophages to hemoglobin. Circ Res 2006; 99: 943-50.
12. Fall N, Barnes M, Thornton S, Luyrink L, Olson J, Ilowite NT, et al. Gene expression profiling of peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum 2007; 56: 3793-804.
13. reg-intrinsic, SOCS3-associated pathways. Blood 2011; 117: 3793-8.
14. Chang CH, Curtis JD, Maggi LB Jr, Faubert B, Villarino AV, O'Sullivan D, et al. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell 2013; 153: 1239-51.
15. Mukhopadhyay S, Varin A, Chen Y, Liu B, Tryggvason K, Gordon S,. SR-A/MARCO-mediated ligand delivery enhances intracellular TLR and NLR function, but ligand scavenging from cell surface limits TLR4 response to pathogens. Blood 2011; 117: 1319-28.