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Volumn 24, Issue 1, 2012, Pages 113-118

Not all hemophagocytes are created equally: Appreciating the heterogeneity of the hemophagocytic syndromes

Author keywords

Cytokine; Hemophagocytosis; Macrophage activation syndrome

Indexed keywords

INTERLEUKIN 6; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RITUXIMAB; TOLL LIKE RECEPTOR;

EID: 82955237596     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0b013e32834dd37e     Document Type: Review
Times cited : (52)

References (38)
  • 1
    • 77955172764 scopus 로고    scopus 로고
    • Macrophage activation syndrome: Advances towards understanding pathogenesis
    • Grom AA, Mellins ED. Macrophage activation syndrome: Advances towards understanding pathogenesis. Curr Opin Rheumatol 2010; 22: 561-566.
    • (2010) Curr Opin Rheumatol , vol.22 , pp. 561-566
    • Grom, A.A.1    Mellins, E.D.2
  • 2
    • 68849131525 scopus 로고    scopus 로고
    • Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation
    • Castillo L, Carcillo J. Secondary hemophagocytic lymphohistiocytosis and severe sepsis/systemic inflammatory response syndrome/multiorgan dysfunction syndrome/macrophage activation syndrome share common intermediate phenotypes on a spectrum of inflammation. Pediatr Crit Care Med 2009; 10:387-392.
    • (2009) Pediatr Crit Care Med , vol.10 , pp. 387-392
    • Castillo, L.1    Carcillo, J.2
  • 3
    • 33646776086 scopus 로고    scopus 로고
    • Peripheral hemophagocytosis: An early indicator of advanced systemic inflammatory response syndrome/hemophagocytic syndrome
    • Kuwata K, Yamada S, Kinuwaki E, et al. Peripheral hemophagocytosis: An early indicator of advanced systemic inflammatory response syndrome/ hemophagocytic syndrome. Shock 2006; 25:344-350.
    • (2006) Shock , vol.25 , pp. 344-350
    • Kuwata, K.1    Yamada, S.2    Kinuwaki, E.3
  • 4
    • 77957736074 scopus 로고    scopus 로고
    • Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation
    • Milner JD, Orekov T, Ward JM, et al. Sustained IL-4 exposure leads to a novel pathway for hemophagocytosis, inflammation, and tissue macrophage accumulation. Blood 2010; 116:2476-2483.
    • (2010) Blood , vol.116 , pp. 2476-2483
    • Milner, J.D.1    Orekov, T.2    Ward, J.M.3
  • 5
    • 77949666728 scopus 로고    scopus 로고
    • Chronic murine typhoid fever is a natural model of secondary hemophagocytic lymphohistiocytosis
    • Brown DE, McCoy MW, Pilonieta MC, et al. Chronic murine typhoid fever is a natural model of secondary hemophagocytic lymphohistiocytosis. PLoS One 2010; 5:e944.
    • (2010) PLoS One , vol.5
    • Brown, D.E.1    McCoy, M.W.2    Pilonieta, M.C.3
  • 8
    • 77951676108 scopus 로고    scopus 로고
    • Inherited defects in lymphocyte cytotoxic activity
    • Pachlopnik Schmid J, Cote M, Menager MM, et al. Inherited defects in lymphocyte cytotoxic activity. Immunol Rev 2010; 235:10-23.
    • (2010) Immunol Rev , vol.235 , pp. 10-23
    • Pachlopnik Schmid, J.1    Cote, M.2    Menager, M.M.3
  • 9
    • 34248666067 scopus 로고    scopus 로고
    • Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis
    • Behrens EM, Beukelman T, Paessler M, et al. Occult macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis. J Rheumatol 2007; 34:1133-1138. (Pubitemid 46774861)
    • (2007) Journal of Rheumatology , vol.34 , Issue.5 , pp. 1133-1138
    • Behrens, E.M.1    Beukelman, T.2    Paessler, M.3    Cron, R.Q.4
  • 10
    • 48249124990 scopus 로고    scopus 로고
    • The role of the initial bone marrow aspirate in the diagnosis of hemophagocytic lymphohistiocytosis
    • Gupta A, Tyrrell P, Valani R, et al. The role of the initial bone marrow aspirate in the diagnosis of hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2008; 51:402-404.
    • (2008) Pediatr Blood Cancer , vol.51 , pp. 402-404
    • Gupta, A.1    Tyrrell, P.2    Valani, R.3
  • 12
    • 79953309677 scopus 로고    scopus 로고
    • An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis
    • Davi S, Consolaro A, Guseinova D, et al. An international consensus survey of diagnostic criteria for macrophage activation syndrome in systemic juvenile idiopathic arthritis. J Rheumatol 2011; 38:764-768.
    • (2011) J Rheumatol , vol.38 , pp. 764-768
    • Davi, S.1    Consolaro, A.2    Guseinova, D.3
  • 13
    • 78649639743 scopus 로고    scopus 로고
    • Rate of decline of ferritin in patients with hemophagocytic lymphohistiocytosis as a prognostic variable for mortality
    • Lin TF, Ferlic-Stark LL, Allen CE, et al. Rate of decline of ferritin in patients with hemophagocytic lymphohistiocytosis as a prognostic variable for mortality. Pediatr Blood Cancer 2011; 56:154-155.
    • (2011) Pediatr Blood Cancer , vol.56 , pp. 154-155
    • Lin, T.F.1    Ferlic-Stark, L.L.2    Allen, C.E.3
  • 14
    • 79954503180 scopus 로고    scopus 로고
    • Serum neopterin levels as a diagnostic marker of hemophagocytic lymphohistiocytosis syndrome
    • Ibarra MF, Klein-Gitelman M, Morgan E, et al. Serum neopterin levels as a diagnostic marker of hemophagocytic lymphohistiocytosis syndrome. Clin Vaccine Immunol 2011; 18:609-614.
    • (2011) Clin Vaccine Immunol , vol.18 , pp. 609-614
    • Ibarra, M.F.1    Klein-Gitelman, M.2    Morgan, E.3
  • 15
    • 77956305107 scopus 로고    scopus 로고
    • A novel assay for investigation of suspected familial haemophagocytic lymphohistiocytosis
    • Wheeler RD, Cale CM, Cetica V, et al. A novel assay for investigation of suspected familial haemophagocytic lymphohistiocytosis. Br J Haematol 2010; 150:727-730.
    • (2010) Br J Haematol , vol.150 , pp. 727-730
    • Wheeler, R.D.1    Cale, C.M.2    Cetica, V.3
  • 16
    • 79958292813 scopus 로고    scopus 로고
    • Hemophagocytosis causes a consumptive anemia of inflammation
    • Zoller EE, Lykens JE, Terrell CE, et al. Hemophagocytosis causes a consumptive anemia of inflammation. J Exp Med 2011; 208:1203-1214.
    • (2011) J Exp Med , vol.208 , pp. 1203-1214
    • Zoller, E.E.1    Lykens, J.E.2    Terrell, C.E.3
  • 17
    • 33749242775 scopus 로고    scopus 로고
    • Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis
    • DOI 10.1111/j.1600-0609.2006.00730.x
    • Schaer DJ, Schaer CA, Schoedon G, et al. Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis. Eur J Haematol 2006; 77:432-436. (Pubitemid 44483947)
    • (2006) European Journal of Haematology , vol.77 , Issue.5 , pp. 432-436
    • Schaer, D.J.1    Schaer, C.A.2    Schoedon, G.3    Imhof, A.4    Kurrer, M.O.5
  • 18
    • 79960714121 scopus 로고    scopus 로고
    • Perforin is a critical physiologic regulator of T-cell activation
    • Lykens JE, Terrell CE, Zoller EE, et al. Perforin is a critical physiologic regulator of T-cell activation. Blood 2011; 118:618-626.
    • (2011) Blood , vol.118 , pp. 618-626
    • Lykens, J.E.1    Terrell, C.E.2    Zoller, E.E.3
  • 19
    • 0037338925 scopus 로고    scopus 로고
    • Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome
    • DOI 10.1067/mpd.2003.110
    • Grom AA, Villanueva J, Lee S, et al. Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome. J Pediatr 2003; 142:292-296. (Pubitemid 36338013)
    • (2003) Journal of Pediatrics , vol.142 , Issue.3 , pp. 292-296
    • Grom, A.A.1    Villanueva, J.2    Lee, S.3    Goldmuntz, E.A.4    Passo, M.H.5    Filipovich, A.6
  • 20
    • 77950531755 scopus 로고    scopus 로고
    • Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis
    • Vastert SJ, van Wijk R, D'Urbano LE, et al. Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis. Rheumatology 2010; 49:441-449.
    • (2010) Rheumatology , vol.49 , pp. 441-449
    • Vastert, S.J.1    Van Wijk, R.2    D'Urbano, L.E.3
  • 21
    • 49749127387 scopus 로고    scopus 로고
    • Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms
    • Zhang K, Biroschak J, Glass DN, et al. Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13-4 polymorphisms. Arthritis Rheum 2008; 58:2892-2896.
    • (2008) Arthritis Rheum , vol.58 , pp. 2892-2896
    • Zhang, K.1    Biroschak, J.2    Glass, D.N.3
  • 22
    • 77951822160 scopus 로고    scopus 로고
    • Cytokine profiles of macrophage activation syndrome associated with rheumatic diseases
    • Maruyama J, Inokuma S. Cytokine profiles of macrophage activation syndrome associated with rheumatic diseases. J Rheumatol 2010; 37: 967-973.
    • (2010) J Rheumatol , vol.37 , pp. 967-973
    • Maruyama, J.1    Inokuma, S.2
  • 23
    • 77955751173 scopus 로고    scopus 로고
    • Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis
    • Shimizu M, Yokoyama T, Yamada K, et al. Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis. Rheumatology 2010; 49:1645-1653.
    • (2010) Rheumatology , vol.49 , pp. 1645-1653
    • Shimizu, M.1    Yokoyama, T.2    Yamada, K.3
  • 24
    • 79957623393 scopus 로고    scopus 로고
    • A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice
    • Sato K, Misawa N, Nie C, et al. A novel animal model of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in humanized mice. Blood 2011; 117:5663-5673.
    • (2011) Blood , vol.117 , pp. 5663-5673
    • Sato, K.1    Misawa, N.2    Nie, C.3
  • 25
    • 79954599747 scopus 로고    scopus 로고
    • Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis
    • Sumegi J, Barnes MG, Nestheide SV, et al. Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis. Blood 2011; 117:e151-e160.
    • (2011) Blood , vol.117
    • Sumegi, J.1    Barnes, M.G.2    Nestheide, S.V.3
  • 26
    • 79959242566 scopus 로고    scopus 로고
    • Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice
    • Krebs P, Crozat K, Popkin D, et al. Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice. Blood 2011; 117:6582-6588.
    • (2011) Blood , vol.117 , pp. 6582-6588
    • Krebs, P.1    Crozat, K.2    Popkin, D.3
  • 28
    • 79957889288 scopus 로고    scopus 로고
    • Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice
    • Behrens EM, Canna SW, Slade K, et al. Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice. J Clin Invest 2011; 121:2264-2277.
    • (2011) J Clin Invest , vol.121 , pp. 2264-2277
    • Behrens, E.M.1    Canna, S.W.2    Slade, K.3
  • 29
    • 71649101226 scopus 로고    scopus 로고
    • Emerging roles of TLR7 and TLR9 in murine SLE
    • Santiago-Raber ML, Baudino L, Izui S. Emerging roles of TLR7 and TLR9 in murine SLE. J Autoimmun 2009; 33:231-238.
    • (2009) J Autoimmun , vol.33 , pp. 231-238
    • Santiago-Raber, M.L.1    Baudino, L.2    Izui, S.3
  • 30
    • 40449107086 scopus 로고    scopus 로고
    • TLR9 contributes to antiviral immunity during gammaherpesvirus infection
    • Guggemoos S, Hangel D, Hamm S, et al. TLR9 contributes to antiviral immunity during gammaherpesvirus infection. J Immunol 2008; 180:438-443.
    • (2008) J Immunol , vol.180 , pp. 438-443
    • Guggemoos, S.1    Hangel, D.2    Hamm, S.3
  • 31
    • 79953301748 scopus 로고    scopus 로고
    • Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis
    • Yanagimachi M, Naruto T, Miyamae T, et al. Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis. J Rheumatol 2011 ; 38:769-774.
    • (2011) J Rheumatol , vol.38 , pp. 769-774
    • Yanagimachi, M.1    Naruto, T.2    Miyamae, T.3
  • 32
    • 80051601409 scopus 로고    scopus 로고
    • Reduced-intensity conditioning haematopoietic cell transplantation for haemophagocytic lymphohistiocytosis: An important step forward
    • Marsh RA, Jordan MB, Filipovich AH. Reduced-intensity conditioning haematopoietic cell transplantation for haemophagocytic lymphohistiocytosis: An important step forward. Br J Haematol 2011; 154:556-563.
    • (2011) Br J Haematol , vol.154 , pp. 556-563
    • Marsh, R.A.1    Jordan, M.B.2    Filipovich, A.H.3
  • 33
    • 77954244065 scopus 로고    scopus 로고
    • Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis
    • Strout MP, Seropian S, Berliner N. Alemtuzumab as a bridge to allogeneic SCT in atypical hemophagocytic lymphohistiocytosis. Nat Rev Clin Oncol 2010; 7:415-420.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 415-420
    • Strout, M.P.1    Seropian, S.2    Berliner, N.3
  • 34
    • 78651365935 scopus 로고    scopus 로고
    • Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids
    • Bruck N, Suttorp M, Kabus M, et al. Rapid and sustained remission of systemic juvenile idiopathic arthritis-associated macrophage activation syndrome through treatment with anakinra and corticosteroids. J Clin Rheumatol 2011; 17:23-27.
    • (2011) J Clin Rheumatol , vol.17 , pp. 23-27
    • Bruck, N.1    Suttorp, M.2    Kabus, M.3
  • 35
    • 78751681576 scopus 로고    scopus 로고
    • Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: Case series with 12 patients
    • Miettunen PM, Narendran A, Jayanthan A, et al. Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: Case series with 12 patients. Rheumatology 2011; 50:417-419.
    • (2011) Rheumatology , vol.50 , pp. 417-419
    • Miettunen, P.M.1    Narendran, A.2    Jayanthan, A.3
  • 36
    • 79952421684 scopus 로고    scopus 로고
    • Successful use of infliximab in macrophage activation syndrome with severe CNS involvement
    • Sellmer A, Stausbol-Gron B, Krag-Olsen B, et al. Successful use of infliximab in macrophage activation syndrome with severe CNS involvement. Scand J Rheumatol 2011; 40:156-157.
    • (2011) Scand J Rheumatol , vol.40 , pp. 156-157
    • Sellmer, A.1    Stausbol-Gron, B.2    Krag-Olsen, B.3
  • 37
    • 3242752040 scopus 로고    scopus 로고
    • + T cells and interferon gamma are essential for the disorder
    • DOI 10.1182/blood-2003-10-3413
    • Jordan MB, Hildeman D, Kappler J, et al. An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder. Blood 2004; 104:735-743. (Pubitemid 38970567)
    • (2004) Blood , vol.104 , Issue.3 , pp. 735-743
    • Jordan, M.B.1    Hildeman, D.2    Kappler, J.3    Marrack, P.4
  • 38
    • 34548406426 scopus 로고    scopus 로고
    • Use of rituximab in conjunction with immunosuppressive chemotherapy as a novel therapy for Epstein Barr virus-associated hemophagocytic lymphohistiocytosis
    • DOI 10.1097/MPH.0b013e3180f61be3, PII 0004342620070800000011
    • Balamuth NJ, Nichols KE, Paessler M, et al. Use of rituximab in conjunction with immunosuppressive chemotherapy as a novel therapy for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. J Pediatr Hematol Oncol 2007; 29:569-573. (Pubitemid 47356813)
    • (2007) Journal of Pediatric Hematology/Oncology , vol.29 , Issue.8 , pp. 569-573
    • Balamuth, N.J.1    Nichols, K.E.2    Paessler, M.3    Teachey, D.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.