CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function

Immunology Letters

Volumn 161, Issue 1, 2014, Pages 65-75

  Girard, Tanya ^a,b   Gaucher, Denis ^b,c,e   El Far, Mohamed ^b,c,f   Breton, Gaëlle ^b,c,g   Sékaly, Rafick Pierre ^a,b,c,d  

^a MCGILL UNIVERSITY   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

^d Vaccine and Gene Therapy Institute of Florida   (United States)

^e MCGILL UNIVERSITY   (Canada)

^f MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^g Laboratory of Cellular Physiology and Immunology The Rocke feller University   (United States)

Author keywords

CD80; CD86; CTLA 4; Immunoglobulin; T cells

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; CD28 ANTIGEN; INTERLEUKIN 2; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; IMMUNOGLOBULIN CONSTANT REGION; IMMUNOGLOBULIN VARIABLE REGION; INTRACELLULAR SIGNALING; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; RECEPTOR BINDING; T LYMPHOCYTE ACTIVATION; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE; CHEMISTRY; FLOW CYTOMETRY; GENE DELETION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PROTEIN DOMAIN; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION;

ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, CD86; CELL LINE; CELL MEMBRANE; CTLA-4 ANTIGEN; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SEQUENCE DELETION; SIGNAL TRANSDUCTION;

EID: 84901600656     PISSN: 01652478     EISSN: 18790542     Source Type: Journal    
DOI: 10.1016/j.imlet.2014.05.002     Document Type: Article

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