In vivo selection of biocompatible alginates for islet encapsulation and subcutaneous transplantation

Tissue Engineering - Part A

Volumn 16, Issue 5, 2010, Pages 1503-1513

  Vériter, Sophie ^a   Mergen, Julien ^a   Goebbels, Rose Marie ^a   Aouassar, Najima ^a   Grégoire, Charles ^a   Jordan, Bénédicte ^a   Levêque, Philippe ^a   Gallez, Bernard ^a   Gianello, Pierre ^a   Dufrane, Denis ^a  

^a UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCOMPATIBILITY; CELL ADHESION; MERCURY (METAL); OXYGEN; PEPTIDES; RATS; VISCOSITY;

ANGIOGENESIS; ELECTRONIC PARAMAGNETIC RESONANCE; ENCAPSULATED CELL; GULURONIC ACID; HIGH-CONTENT; IMMUNOPROTECTION; IN-VIVO; LOW VISCOSITY; MATRIX; NEOVASCULARIZATION; OXIMETRY; OXYGEN DIFFUSION; OXYGEN PRESSURE; PEPTIDE SEQUENCES; SMALL MOLECULES; SUBCUTANEOUS TISSUES; WISTAR RAT;

ALGINATE;

RATTUS; RATTUS NORVEGICUS; SUIDAE;

ALGINIC ACID; BIOMATERIAL; OXYGEN;

ANGIOGENESIS; ANIMAL; ARTICLE; CELL MOTION; CYTOLOGY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; IMPLANT; INFLAMMATION; MACROPHAGE; MATERIALS TESTING; METABOLISM; METHODOLOGY; PANCREAS ISLET; PANCREAS ISLET TRANSPLANTATION; PATHOLOGY; PERMEABILITY; RAT; SUBCUTANEOUS TISSUE; SWINE; WISTAR RAT;

ALGINATES; ANIMALS; BIOCOMPATIBLE MATERIALS; CELL MOVEMENT; DIABETES MELLITUS, EXPERIMENTAL; IMPLANTS, EXPERIMENTAL; INFLAMMATION; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MACROPHAGES; MATERIALS TESTING; NEOVASCULARIZATION, PHYSIOLOGIC; OXYGEN; PERMEABILITY; RATS; RATS, WISTAR; SUBCUTANEOUS TISSUE; SUS SCROFA;

EID: 77953825835     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0286     Document Type: Article

References (53)

1. Shapiro, A.M., Lakey, J.R., Ryan, E.A., Korbutt, G.S., Toth, E., Warnock, G.L., Kneteman, N.M., and Rajotte, R.V. Islet transplantation in seven patients with type 1 diabetes mel-litus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 343, 230, 2000.
2. Ryan, E.A., Paty, B.W., Senior, P.A., Bigam, D., Alfadhli, E., Kneteman, N.M., Lakey, J.R., and Shapiro, A.M. Five-year follow-up after clinical islet transplantation. Diabetes 54, 2060, 2005.
3. Mineo, D., Ricordi, C., Xu, X., Pileggi, A., Garcia-Morales, R., Khan, A., Baidal, D.A., Han, D., Monroy, K., Miller, J., Pugliese, A., Froud, T., Inverardi, L., Kenyon, N.S., and Alejandro, R. Combined islet and hematopoietic stem cell allotransplantation: a clinical pilot trial to induce chimerism and graft tolerance. Am J Transplant 8, 1262, 2008.
4. Shapiro, A.M., Ricordi, C., Hering, B.J., Auchincloss, H., Lindblad, R., Robertson, R.P., Secchi, A., Brendel, M.D., Berney, T., Brennan, D.C., Cagliero, E., Alejandro, R., Ryan, E.A., DiMercurio, B., Morel, P., Polonsky, K.S., Reems, J.A., Bretzel, R.G., Bertuzzi, F., Froud, T., Kandaswamy, R., Sutherland, D.E., Eisenbarth, G., Segal, M., Preiksaitis, J., Korbutt, G.S., Barton, F.B., Viviano, L., Seyfert-Margolis, V., Bluestone, J., and Lakey, J.R. International trial of the Edmonton protocol for islet transplantation. N Engl J Med 355, 1318, 2006.
5. Hirshberg, B., Rother, K.I., Digon, B.J., III, Lee, J., Gaglia, J.L., Hines, K., Read, E.J., Chang, R., Wood, B.J., and Harlan, D.M. Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience. Diabetes Care 26, 3288, 2003.
6. Ryan, E.A., Lakey, J.R., Paty, B.W., Imes, S., Korbutt, G.S., Kneteman, N.M., Bigam, D., Rajotte, R.V., and Shapiro, A.M. Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes 51, 2148, 2002.
7. de Groot, M., Schuurs, T.A., and Van Schilfgaarde, R. Causes of limited survival of microencapsulated pancreatic islet grafts. J Surg Res 121, 141, 2004.
8. De Vos, P., Hamel, A.F., and Tatarkiewicz, K. Considerations for successful transplantation of encapsulated pancreatic islets. Diabetologia 45, 159, 2002.
9. Knazek, R.A., Gullino, P.M., Kohler, P.O., and Dedrick, R.L. Cell culture on artificial capillaries: an approach to tissue growth in vitro. Science 178, 65, 1972.
10. Chick, W.L., Like, A.A., and Lauris, V. Beta cell culture on synthetic capillaries: an artificial endocrine pancreas. Science 187, 847, 1975.
11. Scharp, D.W. Isolation and transplantation of islet tissue. World J Surg 8, 143, 1984.
12. Efrat, S. Cell replacement therapy for type 1 diabetes. Trends Mol Med 8, 334, 2002.
13. Lim, F., and Sun, A.M. Microencapsulated islets as bioarti-ficial endocrine pancreas. Science 210, 908, 1980.
14. De Vos, P., Van Straaten, J.F., Nieuwenhuizen, A.G., de Groot, M., Ploeg, R.J., De Haan, B.J., and Van Schilfgaarde, R. Why do microencapsulated islet grafts fail in the absence of fibrotic overgrowth? Diabetes 48, 1381, 1999.
15. De Vos, P., De Haan, B.J., Wolters, G.H., Strubbe, J.H., and Van Schilfgaarde, R. Improved biocompatibility but limited graft survival after purification of alginate for microencap-sulation of pancreatic islets. Diabetologia 40, 262, 1997.
16. King, A., Lau, J., Nordin, A., Sandler, S., and Andersson, A. The effect of capsule composition in the reversal of hypergly-cemia in diabetic mice transplanted with microencapsulated allogeneic islets. Diabetes Technol Ther 5, 653, 2003.
17. Fritschy, W.M., De Vos, P., Groen, H., Klatter, F.A., Pasma, A., Wolters, G.H., and Van Schilfgaarde, R. The capsular overgrowth on microencapsulated pancreatic islet grafts in streptozotocin and autoimmune diabetic rats. Transpl Int 7, 264, 1994.
18. De Vos, P., De Haan, B.J., and Van Schilfgaarde, R. Up-scaling the production of microencapsulated pancreatic islets. Biomaterials 18, 1085, 1997.
19. De Vos, P., Smedema, I., van Goor, H., Moes, H., van Zan-ten, J., Netters, S., de Leij, L.F., de Haan, A., and De Haan, B.J. Association between macrophage activation and function of micro-encapsulated rat islets. Diabetologia 46, 666, 2003.
20. Iwata, H., Kobayashi, K., Takagi, T., Oka, T., Yang, H., Amemiya, H., Tsuji, T., and Ito, F. Feasibility of agarose microbeads with xenogeneic islets as a bioartificial pancreas. J Biomed Mater Res 28, 1003, 1994.
21. Zielinski, B.A., and Aebischer, P. Chitosan as a matrix for mammalian cell encapsulation. Biomaterials 15, 1049, 1994.
22. Kessler, L., Legeay, G., Jesser, C., Damge, C., and Pinget, M. Influence of corona surface treatment on the properties of an artificial membrane used for Langerhans islets encapsulation: permeability and biocompatibility studies. Biomaterials 16, 185, 1995.
23. Klomp, G.F., Hashiguchi, H., Ursell, P.C., Takeda, Y., Ta-guchi, T., and Dobelle, W.H. Macroporous hydrogel membranes for a hybrid artificial pancreas. II. Biocompatibility. J Biomed Mater Res 17, 865, 1983.
24. Zondervan, G.J., Hoppen, H.J., Pennings, A.J., Fritschy, W., Wolters, G., and Van Schilfgaarde, R. Design of a polyure-thane membrane for the encapsulation of islets of Langer-hans. Biomaterials 13, 136, 1992.
25. Sawhney, A.S., and Hubbell, J.A. Poly(ethylene oxide)-graft-poly(L- lysine) copolymers to enhance the biocompatibility of poly(L-lysine)-alginate microcapsule membranes. Biomaterials 13, 863, 1992.
26. Campos-Lisboa, A.C., Mares-Guia, T.R., Grazioli, G., Goldberg, A.C., and Sogayar, M.C. Biodritin microencapsulated human islets of Langerhans and their potential for type 1 diabetes mellitus therapy. Transplant Proc 40, 433, 2008.
27. Dufrane, D., Goebbels, R.M., Saliez, A., Guiot, Y., and Gia-nello, P. Six-month survival of microencapsulated pig islets and alginate biocompatibility in primates: proof of concept. Transplantation 81, 1345, 2006.
28. De Vos, P., De Haan, B.J., de Haan, A., van Zanten, J., and Faas, M.M. Factors influencing functional survival of mi-croencapsulated islet grafts. Cell Transplant 13, 515, 2004.
29. Schneider, S., Feilen, P.J., Brunnenmeier, F., Minnemann, T., Zimmermann, H., Zimmermann, U., and Weber, M.M. Long-term graft function of adult rat and human islets encapsulated in novel alginate-based microcapsules after transplantation in immunocompetent diabetic mice. Diabetes 54, 687, 2005.
30. Elliott, R.B., Escobar, L., Tan, P.L., Muzina, M., Zwain, S., and Buchanan, C. Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation. Xe-notransplantation 14, 157, 2007.
31. De Vos, P., Faas, M.M., Strand, B., and Calafiore, R. Algi-nate-based microcapsules for immunoisolation of pancreatic islets. Biomaterials 27, 5603, 2006.
32. Ertesvag, H., and Valla, S. Biosynthesis and applications of alginates. Polym Degrad Stability 59, 85, 1998.
33. Burdick, J.A., and Anseth, K.S. Photoencapsulation of oste-oblasts in injectable RGD-modified PEG hydrogels for bone tissue engineering. Biomaterials 23, 4315, 2002.
34. Evangelista, M.B., Hsiong, S.X., Fernandes, R., Sampaio, P., Kong, H.J., Barrias, C.C., Salema, R., Barbosa, M.A., Moon-ey, D.J., and Granja, P.L. Upregulation of bone cell differentiation through immobilization within a synthetic extracellular matrix. Biomaterials 28, 3644, 2007.
35. Orive, G., Tam, S.K., Pedraz, J.L., and Halle, J.P. Bio-compatibility of alginate-poly-l-lysine microcapsules for cell therapy. Biomaterials 27, 3691, 2006.
36. Dufrane, D., van Steenberghe, M., Goebbels, R.M., Saliez, A., Guiot, Y., and Gianello, P. The influence of implantation site on the biocompatibility and survival of alginate encapsulated pig islets in rats. Biomaterials 27, 3201, 2006.
37. Abstracts of the Joint Meeting of the International Xenotransplantation Association (IXA), the International Pancreas and Islet Transplant Association (IPITA), and the Cell Transplant Society (CTS), Minneapolis, MN, September 15-20, 2007. Xenotransplantation 14, 375, 2007.
38. Barnett, B.P., Kraitchman, D.L., Lauzon, C., Magee, C.A., Walczak, P., Gilson, W.D., Arepally, A., and Bulte, J.W. Radiopaque alginate microcapsules for X-ray visualization and immunoprotection of cellular therapeutics. Mol Pharm 3, 531, 2006.
39. Gallez, B., Baudelet, C., and Jordan, B.F. Assessment of tumor oxygenation by electron paramagnetic resonance: principles and applications. NMR Biomed 17, 240, 2004.
40. Gallez, B., Jordan, B.F., Baudelet, C., and Misson, P.D. Pharmacological modifications of the partial pressure of oxygen in murine tumors: evaluation using in vivo EPR oximetry. Magn Reson Med 42, 627, 1999.
41. Dufrane, D., D'hoore, W., Goebbels, R.M., Saliez, A., Guiot, Y., and Gianello, P. Parameters favouring successful adult pig islet isolations for xenotransplantation in pig-to-primate models. Xenotransplantation 13, 204, 2006.
42. Duvivier-Kali, V.F., Omer, A., Lopez-Avalos, M.D., O'Neil, J.J., and Weir, G.C. Survival of microencapsulated adult pig islets in mice in spite of an antibody response. Am J Transplant 4, 1991, 2004.
43. Gugerli, R., Cantana, E., Heinzen, C., von Stockar, U., and Marison, I.W. Quantitative study of the production and properties of alginate=poly-l-lysine microcapsules. J Micro-encapsul 19, 571, 2002.
44. Goosen, M.F., O'Shea, G.M., Gharapetian, H.M., Chou, S., and Sun, A.M. Optimization of microencapsulation parameters: semipermeable microcapsules as a bioartificial pancreas. Biotechnol Bioeng 27, 146, 1985.
45. Pueyo, M.E., Darquy, S., Capron, F., and Reach, G. In vitro activation of human macrophages by alginate-polylysine microcapsules. J Biomater Sci Polym Ed 5, 197, 1993.
46. Darquy, S., Pueyo, M.E., Capron, F., and Reach, G. Complement activation by alginate-polylysine microcapsules used for islet transplantation. Artif Organs 18, 898, 1994.
47. Strand, B.L., Ryan, T.L., In't, V.P., Kulseng, B., Rokstad, A.M., Skjak-Brek, G., and Espevik, T. Poly-l-lysine induces fibrosis on alginate microcapsules via the induction of cy-tokines. Cell Transplant 10, 263, 2001.
48. De Vos, P., De Haan, B., and Van Schilfgaarde, R. Effect of the alginate composition on the biocompatibility of alginate-polylysine microcapsules. Biomaterials 18, 273, 1997.
49. Clayton, H.A., London, N.J., Colloby, P.S., Bell, P.R., and James, R.F. The effect of capsule composition on the bio-compatibility of alginate-poly-l-lysine capsules. J Micro-encapsul 8, 221, 1991.
50. Carlsson, P.O., and Palm, F. Oxygen tension in isolated transplanted rat islets and in islets of rat whole-pancreas transplants. Transpl Int 15, 581, 2002.
51. Dionne, K.E., Colton, C.K., and Yarmush, M.L. Effect of ox-ygenon isolated pancreatic tissue. ASAIO Trans 35, 739, 1989.
52. Dionne, K.E., Colton, C.K., and Yarmush, M.L. Effect of hypoxia on insulin secretion by isolated rat and canine islets of Langerhans. Diabetes 42, 12, 1993.
53. Carlsson, P.O., Palm, F., Andersson, A., and Liss, P. Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 50, 489, 2001.