Lithium increases nitric oxide levels in subjects with bipolar disorder during depressive episodes

Journal of Psychiatric Research

Volumn 55, Issue 1, 2014, Pages 96-100

  de Sousa, Rafael T ^a   Zanetti, Marcus V ^a   Busatto, Geraldo F ^a   Mouro, Margaret G ^c   Zarate, Carlos A ^b   Gattaz, Wagner F ^a   Higa, Elisa M ^b   Machado Vieira, Rodrigo ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bipolar disorder; Depression; Lithium; Nitric oxide; Plasticity; Treatment

Indexed keywords

LITHIUM; NITRIC OXIDE; ANTIDEPRESSANT AGENT; LITHIUM CARBONATE;

ADULT; ARTICLE; BIPOLAR DEPRESSION; CHEMOLUMINESCENCE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NERVE CELL PLASTICITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; BIPOLAR DISORDER; BLOOD; DEPRESSIVE DISORDER; FOLLOW UP; LUMINESCENCE; PSYCHOLOGICAL RATING SCALE;

ADULT; ANTIDEPRESSIVE AGENTS; BIPOLAR DISORDER; DEPRESSIVE DISORDER; FEMALE; FOLLOW-UP STUDIES; HUMANS; LITHIUM CARBONATE; LUMINESCENCE; MALE; NITRIC OXIDE; PSYCHIATRIC STATUS RATING SCALES;

EID: 84901472441     PISSN: 00223956     EISSN: 18791379     Source Type: Journal    
DOI: 10.1016/j.jpsychires.2014.03.023     Document Type: Article

References (46)

1. Acar G., Idiman F., Idiman E., Kirkali G., Cakmakçi H., Ozakbaş S. Nitric oxide as an activity marker in multiple sclerosis. JNeurol 2003, 250:588-592.
2. Anai H., Ueta Y., Serino R., Nomura M., Nakashima Y., Yamashita H. Activation of hypothalamic neuronal nitric oxide synthase in lithium-induced diabetes insipidus rats. Psychoneuroendocrinology 2001, 26:109-120.
3. Andreazza A.C., Kauer-Sant'anna M., Frey B.N., Bond D.J., Kapczinski F., Young L.T., et al. Oxidative stress markers in bipolar disorder: a meta-analysis. JAffect Disord 2008, 111:135-144.
4. Bagetta G., Corasaniti M.T., Melino G., Paoletti A.M., Finazzi-Agrò A., Nisticò G. Lithium and tacrine increase the expression of nitric oxide synthase mRNA in the hippocampus of rat. Biochem Biophys Res Commun 1993, 197:1132-1139.
5. Bandino A., Compagnone A., Bravoco V., Cravanzola C., Lomartire A., Rossetto C., et al. Beta-catenin triggers nuclear factor kappaB-dependent up-regulation of hepatocyte inducible nitric oxide synthase. Int J Biochem Cell Biol 2008, 40:1861-1871.
6. Bernstein H.G., Heinemann A., Krell D., Dobrowolny H., Bielau H., Keilhoff G., et al. Hypothalamic nitric oxide synthase in affective disorder: focus on the suprachiasmatic nucleus. Cell Mol Biol (Noisy-le-grand) 2005, 51:279-284.
7. Bernstein H.G., Heinemann A., Krell D., Mawrin C., Bielau H., Danos P., et al. Further immunohistochemical evidence for impaired NO signaling in the hypothalamus of depressed patients. Ann N Y Acad Sci 2002, 973:91-93.
8. Bernstein H.G., Stanarius A., Baumann B., Henning H., Krell D., Danos P., et al. Nitric oxide synthase-containing neurons in the human hypothalamus: reduced number of immunoreactive cells in the paraventricular nucleus of depressive patients and schizophrenics. Neuroscience 1998, 83:867-875.
9. Bhalla P., Singla N., Dhawan D.K. Potential of lithium to reduce aluminium-induced cytotoxic effects in rat brain. Biometals 2010, 23:197-206.
10. Bon C.L., Garthwaite J. On the role of nitric oxide in hippocampal long-term potentiation. JNeurosci 2003, 23:1941-1948.
11. Bschor T., Bauer M. Efficacy and mechanisms of action of lithium augmentation in refractory major depression. Curr Pharm Des 2006, 12:2985-2992.
12. Calabrese V., Mancuso C., Calvani M., Rizzarelli E., Butterfield D.A., Stella A.M. Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity. Nat Rev Neurosci 2007, 8:766-775.
13. Chrapko W.E., Jurasz P., Radomski M.W., Lara N., Archer S.L., Le Mellédo J.M. Decreased platelet nitric oxide synthase activity and plasma nitric oxide metabolites in major depressive disorder. Biol Psychiatry 2004, 56:129-134.
14. Ciani E., Virgili M., Contestabile A. Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones. JNeurochem 2002, 81:218-228.
15. de Sousa R.T., van de Bilt M.T., Diniz B.S., Ladeira R.B., Portela L.V., Souza D.O., et al. Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: a preliminary 4-week study. Neurosci Lett 2011, 494:54-56.
16. Du Q., Park K.S., Guo Z., He P., Nagashima M., Shao L., et al. Regulation of human nitric oxide synthase 2 expression by Wnt beta-catenin signaling. Cancer Res 2006, 66:7024-7031.
17. Feinstein D.L. Potentiation of astroglial nitric oxide synthase type-2 expression by lithium chloride. JNeurochem 1998, 71:883-886.
18. First M., Riswan S., Mike G., Jbw W. Structured clinical interview for DSM-IV Axis I disorders 1995, Biometrics Research Department, New York Psychiatric Institute, New York. Patient ed.
19. García R.G., Zarruk J.G., Barrera C., Pinzón A., Trillos E., Arenas W.D., et al. Plasma nitrate levels and flow-mediated vasodilation in untreated major depression. Psychosom Med 2011, 73:344-349.
20. Ghasemi M., Dehpour A.R. The NMDA receptor/nitric oxide pathway: a target for the therapeutic and toxic effects of lithium. Trends Pharmacol Sci 2011, 32:420-434.
21. Hamilton M. Arating scale for depression. JNeurol Neurosurg Psychiatry 1960, 23:56-62.
22. Hampl V., Waters C., Ascher S. Determination of nitric oxide by the chemiluminescence reaction with ozone. Methods in nitric oxide 1996, 309-318. John Wiley & Sons Ltd. M. Feelisch, J.S. Stamler (Eds.).
23. Harvey B.H., Carstens M.E., Taljaard J.J. Evidence that lithium induces a glutamatergic: nitric oxide-mediated response in rat brain. Neurochem Res 1994, 19:469-474.
24. Herken H., Gurel A., Selek S., Armutcu F., Ozen M.E., Bulut M., et al. Adenosine deaminase, nitric oxide, superoxide dismutase, and xanthine oxidase in patients with major depression: impact of antidepressant treatment. Arch Med Res 2007, 38:247-252.
25. Hunter R.A., Storm W.L., Coneski P.N., Schoenfisch M.H. Inaccuracies of nitric oxide measurement methods in biological media. Anal Chem 2013, 85:1957-1963.
26. Ibragic S., Sofic E., Suljic E., Avdagic N., Bajraktarevic A., Tahirovic I. Serum nitric oxide concentrations in patients with multiple sclerosis and patients with epilepsy. JNeural Transm 2012, 119:7-11.
27. Ikenouchi-Sugita A., Yoshimura R., Hori H., Umene-Nakano W., Ueda N., Nakamura J. Effects of antidepressants on plasma metabolites of nitric oxide in major depressive disorder: comparison between milnacipran and paroxetine. Prog Neuropsychopharmacol Biol Psychiatry 2009, 33:1451-1453.
28. Karolewicz B., Szebeni K., Stockmeier C.A., Konick L., Overholser J.C., Jurjus G., et al. Low nNOS protein in the locus coeruleus in major depression. JNeurochem 2004, 91:1057-1066.
29. Kim Y.K., Paik J.W., Lee S.W., Yoon D., Han C., Lee B.H. Increased plasma nitric oxide level associated with suicide attempt in depressive patients. Prog Neuropsychopharmacol Biol Psychiatry 2006, 30:1091-1096.
30. Lara N., Archer S.L., Baker G.B., Le Mellédo J.M. Paroxetine-induced increase in metabolic end products of nitric oxide. JClin Psychopharmacol 2003, 23:408-412.
31. Liu L., Stamler J.S. NO: an inhibitor of cell death. Cell Death Differ 1999, 6:937-942.
32. Machado-Vieira R., Manji H.K., Zarate C.A. The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis. Bipolar Disord 2009, 11(Suppl.2):92-109.
33. Maia-de-Oliveira J.P., Trzesniak C., Oliveira I.R., Kempton M.J., Rezende T.M., Iego S., et al. Nitric oxide plasma/serum levels in patients with schizophrenia: a systematic review and meta-analysis. Rev Bras Psiquiatr 2012, 34(Suppl.2):S149-S155.
34. Maruta S., Suzuki E., Yokoyama M., Sato T., Inada K., Watanabe S., et al. Effects of intraperitoneally injected lithium, imipramine and diazepam on nitrate levels in rat amygdala. Psychiatry Clin Neurosci 2005, 59:358-361.
35. Petkova E., Quitkin F.M., McGrath P.J., Stewart J.W., Klein D.F. Amethod to quantify rater bias in antidepressant trials. Neuropsychopharmacology 2000, 22:559-565.
36. Prast H., Philippu A. Nitric oxide as modulator of neuronal function. Prog Neurobiol 2001, 64:51-68.
37. Rejdak K., Petzold A., Sharpe M.A., Smith M., Keir G., Stelmasiak Z., et al. Serum and urine nitrate and nitrite are not reliable indicators of intrathecal nitric oxide production in acute brain injury. JNeurol Sci 2003, 208:1-7.
38. Riccio A., Alvania R.S., Lonze B.E., Ramanan N., Kim T., Huang Y., et al. Anitric oxide signaling pathway controls CREB-mediated gene expression in neurons. Mol Cell 2006, 21:283-294.
39. Savas H.A., Gergerlioglu H.S., Armutcu F., Herken H., Yilmaz H.R., Kocoglu E., et al. Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes. World J Biol Psychiatry 2006, 7:51-55.
40. Selek S., Savas H.A., Gergerlioglu H.S., Bulbul F., Uz E., Yumru M. The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode. JAffect Disord 2008, 107:89-94.
41. Selley M.L. Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression. JAffect Disord 2004, 80:249-256.
42. Sergent O., Griffon B., Morel I., Chevanne M., Dubos M.P., Cillard P., et al. Effect of nitric oxide on iron-mediated oxidative stress in primary rat hepatocyte culture. Hepatology 1997, 25:122-127.
43. Suzuki E., Yagi G., Nakaki T., Kanba S., Asai M. Elevated plasma nitrate levels in depressive states. JAffect Disord 2001, 63:221-224.
44. Wada A. Lithium and neuropsychiatric therapeutics: neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades. JPharmacol Sci 2009, 110:14-28.
45. Yang F., Troncy E., Francoeur M., Vinet B., Vinay P., Czaika G., et al. Effects of reducing reagents and temperature on conversion of nitrite and nitrate to nitric oxide and detection of NO by chemiluminescence. Clin Chem 1997, 43:657-662.
46. Yuceyar N., Taşkiran D., Saǧduyu A. Serum and cerebrospinal fluid nitrite and nitrate levels in relapsing-remitting and secondary progressive multiple sclerosis patients. Clin Neurol Neurosurg 2001, 103:206-211.