Activation of a GPCR leads to eIF4G phosphorylation at the 5′ cap and to IRES-dependent translation

Journal of Molecular Endocrinology

Volumn 52, Issue 3, 2014, Pages 373-382

  León, Kelly ^a,b,c,d   Boulo, Thomas ^a,b,c,d   Musnier, Astrid ^a,b,c,d   Morales, Julia ^e,f   Gauthier, Christophe ^a,b,c,d   Dupuy, Laurence ^a,b,c,d,h   Heyne, Steffen ^g   Backofen, Rolf ^g   Poupon, Anne ^a,b,c,d   Cormier, Patrick ^e,f   Reiter, Eric ^a,b,c,d   Crepieux, Pascale ^a,b,c,d  

^a UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

^b CNRS   (France)

^c UNIVERSITÉ DE TOURS   (France)

^d IFCE   (France)

^e SORBONNE UNIVERSITÉ   (France)

^f UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

^g UNIVERSITY OF FREIBURG   (Germany)

^h CEMAGREF   (France)

Author keywords

eIF4G; FSH; GPCR; HEK293 cells; IRES; mRNA translation

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; FOLLITROPIN; FOLLITROPIN RECEPTOR; G PROTEIN COUPLED RECEPTOR; INITIATION FACTOR 4B; INITIATION FACTOR 4E; INITIATION FACTOR 4G; RAPAMYCIN; SULFUR 35; VASCULOTROPIN A; EIF4EBP1 PROTEIN, HUMAN; EIF4G1 PROTEIN, HUMAN; INITIATION FACTOR; MESSENGER RNA; MTOR PROTEIN, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL DENSITY; CELL LYSATE; CONTROLLED STUDY; HEK293 CELL LINE; HORMONAL REGULATION; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RNA TRANSLATION; SEMINIFEROUS TUBULE; SERTOLI CELL; TRANSLATION INITIATION; TRANSLATION REGULATION; BIOSYNTHESIS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHOSPHORYLATION; RIBOSOME; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CELL LINE, TUMOR; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-4G; FOLLICLE STIMULATING HORMONE; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; PEPTIDE INITIATION FACTORS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RECEPTORS, FSH; RIBOSOMES; RNA, MESSENGER; TOR SERINE-THREONINE KINASES;

EID: 84901457401     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-14-0009     Document Type: Article

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