MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle

Science Signaling

Volumn 5, Issue 211, 2012, Pages

  Hu, Shou Ih ^a   Katz, Mark ^a   Chin, Sherry ^a   Qi, Xiaoqing ^a   Cruz, Joseph ^a   Ibebunjo, Chikwendu ^a   Zhao, Shanchuan ^a   Chen, Amy ^a   Glass, David J ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; INITIATION FACTOR 4G; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; RAPAMYCIN; S6 KINASE; SERINE; SERINE ARGININE RICH PROTEIN; SMALL INTERFERING RNA; SOMATOMEDIN C; DEXAMETHASONE; MKNK1 PROTEIN, MOUSE; MKNK2 PROTEIN, MOUSE; PROTEIN SERINE THREONINE KINASE; SRPK1 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; GENE OVEREXPRESSION; HUMAN; MOUSE; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MALNUTRITION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SKELETAL MUSCLE; TRANSLATION INITIATION; ANIMAL; CELL LINE; DRUG EFFECT; GENETICS; METABOLISM; MOUSE MUTANT; MUSCLE ATROPHY; MYOBLAST; PATHOLOGY; PHOSPHORYLATION; PROTEIN BINDING; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STARVATION; WESTERN BLOTTING;

ANIMALS; ARGININE; BLOTTING, WESTERN; CELL LINE; DEXAMETHASONE; EUKARYOTIC INITIATION FACTOR-4G; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR ATROPHY; MYOBLASTS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA INTERFERENCE; SERINE; SIGNAL TRANSDUCTION; SIROLIMUS; STARVATION; TOR SERINE-THREONINE KINASES;

EID: 84857183328     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002466     Document Type: Article

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