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Volumn 4, Issue 5, 2014, Pages

KRAS, NRAS and BRAF mutations in Greek and Romanian patients with colorectal cancer: A cohort study

(15)  Negru, Serban a   Papadopoulou, Eirini b   Apessos, Angela b   Stanculeanu, Dana Lucia c   Ciuleanu, Eliade d   Volovat, Constantin e   Croitoru, Adina f   Kakolyris, Stylianos g   Aravantinos, Gerasimos h   Ziras, Nikolaos i   Athanasiadis, Elias j   Touroutoglou, Nikolaos k   Pavlidis, Nikolaos l   Kalofonos, Haralabos P m   Nasioulas, George b  


Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; K RAS PROTEIN; RAS PROTEIN; BRAF PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; KRAS PROTEIN, HUMAN; MEMBRANE PROTEIN; NRAS PROTEIN, HUMAN; PROTEIN P21;

EID: 84901439503     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2013-004652     Document Type: Article
Times cited : (37)

References (24)
  • 1
    • 77956238031 scopus 로고    scopus 로고
    • NRAS mutations are rare in colorectal cancer
    • Irahara N, Baba Y, Nosho K, et al. NRAS mutations are rare in colorectal cancer. Diagn Mol Pathol 2010;19:157-63.
    • (2010) Diagn Mol Pathol , vol.19 , pp. 157-163
    • Irahara, N.1    Baba, Y.2    Nosho, K.3
  • 2
    • 64049090889 scopus 로고    scopus 로고
    • Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR
    • Heinemann V, Stintzing S, Kirchner T, et al. Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR. Cancer Treat Rev 2009;35:262-71.
    • (2009) Cancer Treat Rev , vol.35 , pp. 262-271
    • Heinemann, V.1    Stintzing, S.2    Kirchner, T.3
  • 3
    • 79952392909 scopus 로고    scopus 로고
    • Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer
    • Vaughn CP, Zobell SD, Furtado LV, et al. Frequency of KRAS, BRAF, and NRAS mutations in colorectal cancer. Genes Chromosomes Cancer 2011;50:307-12.
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 307-312
    • Vaughn, C.P.1    Zobell, S.D.2    Furtado, L.V.3
  • 4
    • 77955277111 scopus 로고    scopus 로고
    • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
    • De Roock W, Claes B, Bernasconi D, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol 2010;11:753-62.
    • (2010) Lancet Oncol , vol.11 , pp. 753-762
    • De Roock, W.1    Claes, B.2    Bernasconi, D.3
  • 5
    • 84891810511 scopus 로고    scopus 로고
    • Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: Clinical outcome and biomarkers of efficacy
    • Pietrantonio F, Perrone F, Biondani P, et al. Single agent panitumumab in KRAS wild-type metastatic colorectal cancer patients following cetuximab-based regimens: clinical outcome and biomarkers of efficacy. Cancer Biol Ther 2013;14:1098-103.
    • (2013) Cancer Biol Ther , vol.14 , pp. 1098-1103
    • Pietrantonio, F.1    Perrone, F.2    Biondani, P.3
  • 6
    • 84883680951 scopus 로고    scopus 로고
    • Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
    • Douillard JY, Oliner KS, Siena S, et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013;369:1023-34.
    • (2013) N Engl J Med , vol.369 , pp. 1023-1034
    • Douillard, J.Y.1    Oliner, K.S.2    Siena, S.3
  • 7
    • 84884493477 scopus 로고    scopus 로고
    • RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases
    • Vauthey JN, Zimmitti G, Kopetz SE, et al. RAS mutation status predicts survival and patterns of recurrence in patients undergoing hepatectomy for colorectal liver metastases. Ann Surg 2013;258:619-272.
    • (2013) Ann Surg , vol.258 , pp. 619-1272
    • Vauthey, J.N.1    Zimmitti, G.2    Kopetz, S.E.3
  • 8
    • 33846641709 scopus 로고    scopus 로고
    • High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer
    • Krypuy M, Newnham GM, Thomas DM, et al. High resolution melting analysis for the rapid and sensitive detection of mutations in clinical samples: KRAS codon 12 and 13 mutations in non-small cell lung cancer. BMC Cancer 2006;6:295.
    • (2006) BMC Cancer , vol.6 , pp. 295
    • Krypuy, M.1    Newnham, G.M.2    Thomas, D.M.3
  • 9
    • 80053174701 scopus 로고    scopus 로고
    • Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing
    • Borràs E, Jurado I, Hernan I, et al. Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing. BMC Cancer 2011;11:406.
    • (2011) BMC Cancer , vol.11 , pp. 406
    • Borràs, E.1    Jurado, I.2    Hernan, I.3
  • 10
    • 77952536391 scopus 로고    scopus 로고
    • Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes
    • Lurkin I, Stoehr R, Hurst CD, et al. Two multiplex assays that simultaneously identify 22 possible mutation sites in the KRAS, BRAF, NRAS and PIK3CA genes. PLoS ONE 2010;5:e8802.
    • (2010) PLoS ONE , vol.5
    • Lurkin, I.1    Stoehr, R.2    Hurst, C.D.3
  • 11
    • 4143084823 scopus 로고    scopus 로고
    • A single, multiplex analysis for all relevant activating NRAS gene mutations using heteroduplex generators
    • DOI 10.1111/j.1365-2141.2004.05079.x
    • Belli C, Bowen DJ, De BRAFi C, et al. A single, multiplex analysis for all relevant activating NRAS gene mutations using heteroduplex generators. Br J Haematol 2004;126:602-5. (Pubitemid 39093104)
    • (2004) British Journal of Haematology , vol.126 , Issue.4 , pp. 602-605
    • Belli, C.1    Bowen, D.J.2    De Brasi, C.3    Larripa, I.4
  • 13
    • 84875483113 scopus 로고    scopus 로고
    • High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer
    • Guedes JG, Veiga I, Rocha P, et al. High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer. BMC Cancer 2013;13:169.
    • (2013) BMC Cancer , vol.13 , pp. 169
    • Guedes, J.G.1    Veiga, I.2    Rocha, P.3
  • 14
    • 84866522096 scopus 로고    scopus 로고
    • High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS, BRAF, PIK3CA, and AKT1 mutations in formalin-fixed, paraffin-embedded tissues
    • Ney JT, Froehner S, Roesler A, et al. High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS, BRAF, PIK3CA, and AKT1 mutations in formalin-fixed, paraffin-embedded tissues. Arch Pathol Lab Med 2012;136:983-92.
    • (2012) Arch Pathol Lab Med , vol.136 , pp. 983-992
    • Ney, J.T.1    Froehner, S.2    Roesler, A.3
  • 15
    • 48649092117 scopus 로고    scopus 로고
    • High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer
    • Simi L, Pratesi N, Vignoli M, et al. High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer. Am J Clin Pathol 2008;130:247-53.
    • (2008) Am J Clin Pathol , vol.130 , pp. 247-253
    • Simi, L.1    Pratesi, N.2    Vignoli, M.3
  • 16
    • 44649156362 scopus 로고    scopus 로고
    • High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies
    • Do H, Krypuy M, Mitchell PL, et al. High resolution melting analysis for rapid and sensitive EGFR and KRAS mutation detection in formalin fixed paraffin embedded biopsies. BMC Cancer 2008;8:142.
    • (2008) BMC Cancer , vol.8 , pp. 142
    • Do, H.1    Krypuy, M.2    Mitchell, P.L.3
  • 17
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-34.
    • (2008) J Clin Oncol , vol.26 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 18
    • 78149250536 scopus 로고    scopus 로고
    • Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
    • Douillard JY, Siena S, Cassidy J, et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol 2010;28:4697-705.
    • (2010) J Clin Oncol , vol.28 , pp. 4697-4705
    • Douillard, J.Y.1    Siena, S.2    Cassidy, J.3
  • 19
    • 78149239651 scopus 로고    scopus 로고
    • Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer
    • Peeters M, Price TJ, Cervantes A, et al. Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J Clin Oncol 2010;28:4706-13.
    • (2010) J Clin Oncol , vol.28 , pp. 4706-4713
    • Peeters, M.1    Price, T.J.2    Cervantes, A.3
  • 20
    • 81355161586 scopus 로고    scopus 로고
    • Uptake of KRAS mutation testing in patients with metastatic colorectal cancer in Europe, Latin America and Asia
    • Ciardiello F, Tejpar S, Normanno N, et al. Uptake of KRAS mutation testing in patients with metastatic colorectal cancer in Europe, Latin America and Asia. Target Oncol 2011;6:133-45.
    • (2011) Target Oncol , vol.6 , pp. 133-145
    • Ciardiello, F.1    Tejpar, S.2    Normanno, N.3
  • 21
    • 84877101402 scopus 로고    scopus 로고
    • Somatic mutations of K-RAS and BRAF in Thai colorectal cancer and their prognostic value
    • Chaiyapan W, Duangpakdee P, Boonpipattanapong T, et al. Somatic mutations of K-RAS and BRAF in Thai colorectal cancer and their prognostic value. Asian Pac J Cancer Prev 2013;14:329-32.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 329-332
    • Chaiyapan, W.1    Duangpakdee, P.2    Boonpipattanapong, T.3
  • 22
    • 68749119351 scopus 로고    scopus 로고
    • KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
    • Loupakis F, Ruzzo A, Cremolini C, et al. KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer 2009;101:715-21.
    • (2009) Br J Cancer , vol.101 , pp. 715-721
    • Loupakis, F.1    Ruzzo, A.2    Cremolini, C.3
  • 24
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008;26:5705-12.
    • (2008) J Clin Oncol , vol.26 , pp. 5705-5712
    • Di Nicolantonio, F.1    Martini, M.2    Molinari, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.