Neuropeptide Y and leptin sensitivity is dependent on diet composition

Journal of Neuroendocrinology

Volumn 26, Issue 6, 2014, Pages 377-385

  van den Heuvel, J K ^a   Eggels, L ^a   van Rozen, A J ^b   Luijendijk, M C M ^b   Fliers, E ^a   Kalsbeek, A ^a,c   Adan, R A H ^b   La Fleur, S E ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

Author keywords

Diets; Food intake; Liquid sugar; Obesity; Saturated fat

Indexed keywords

LEPTIN; MESSENGER RNA; NEUROPEPTIDE Y; SATURATED FATTY ACID; SUGAR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARCUATE NUCLEUS; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; DIET; ENERGY BALANCE; FEEDING BEHAVIOR; FLUORESCENCE IN SITU HYBRIDIZATION; FOOD COMPOSITION; FOOD INTAKE; HYPERPHAGIA; LATERAL BRAIN VENTRICLE; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WISTAR RAT; ANIMAL; BIOSYNTHESIS; DRUG EFFECTS; ENERGY METABOLISM; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; PHYSIOLOGY; WEIGHT GAIN;

ANIMALS; DIET; ENERGY INTAKE; ENERGY METABOLISM; FEEDING BEHAVIOR; INJECTIONS, INTRAVENTRICULAR; LEPTIN; MALE; NEUROPEPTIDE Y; RATS; RATS, WISTAR; WEIGHT GAIN;

EID: 84901405369     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/jne.12155     Document Type: Article

References (44)

1. Cavadini C, Siega-Riz AM, Popkin BM. US adolescent food intake trends from 1965 to 1996. West J Med 2000; 173: 378-383.
2. Macdiarmid J, Loe J, Craig LC, Masson LF, Holmes B, McNeill G. Meal and snacking patterns of school-aged children in Scotland. Eur J Clin Nutr 2009; 63: 1297-1304.
3. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012; 307: 483-490.
4. Woods SC, Seeley RJ, Porte D Jr, Schwartz MW. Signals that regulate food intake and energy homeostasis. Science 1998; 280: 1378-1383.
5. Blomqvist AG, Herzog H. Y-receptor subtypes - how many more? Trends Neurosci 1997; 20: 294-298.
6. Stephens TW, Basinski M, Bristow PK, Bue-Valleskey JM, Burgett SG, Craft L, Hale J, Hoffmann J, Hsiung HM, Kriauciunas A, MacKellar W, Rosteck PR Jr, Schoner B, Smith D, Tinsley FC, Zhang X, Heiman M. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 1995; 377: 530-532.
7. Erickson JC, Clegg KE, Palmiter RD. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 1996; 381: 415-421.
8. Dryden S, Frankish H, Wang Q, Williams G. Neuropeptide Y and energy balance: one way ahead for the treatment of obesity? Eur J Clin Invest 1994; 24: 293-308.
9. Levin BE, Dunn-Meynell AA. Dysregulation of arcuate nucleus preproneuropeptide Y mRNA in diet-induced obese rats. Am J Physiol 1997; 272: R1365-R1370.
10. Huang XF, Han M, Storlien LH. The level of NPY receptor mRNA expression in diet-induced obese and resistant mice. Brain Res Mol Brain Res 2003; 115: 21-28.
11. Giraudo SQ, Kotz CM, Grace MK, Levine AS, Billington CJ. Rat hypothalamic NPY mRNA and brown fat uncoupling protein mRNA after high-carbohydrate or high-fat diets. Am J Physiol 1994; 266: R1578-R1583.
12. la Fleur SE, van Rozen AJ, Luijendijk MC, Groeneweg F, Adan RA. A free-choice high-fat high-sugar diet induces changes in arcuate neuropeptide expression that support hyperphagia. Int J Obes (Lond) 2010; 34: 537-546.
13. Hansen MJ, Jovanovska V, Morris MJ. Adaptive responses in hypothalamic neuropeptide Y in the face of prolonged high-fat feeding in the rat. J Neurochem 2004; 88: 909-916.
14. Andersson U, Filipsson K, Abbott CR, Woods A, Smith K, Bloom SR, Carling D, Small CJ. AMP-activated protein kinase plays a role in the control of food intake. J Biol Chem 2004; 279: 12005-12008.
15. van den Heuvel JK, Eggels L, Fliers E, Kalsbeek A, Adan RA, la Fleur SE. Differential modulation of arcuate nucleus and mesolimbic gene expression levels by central leptin in rats on short-term high-fat high-sugar diet. PLoS One 2014; 9: e87729.
16. la Fleur SE, Luijendijk MC, van Rozen AJ, Kalsbeek A, Adan RA. A free-choice high-fat high-sugar diet induces glucose intolerance and insulin unresponsiveness to a glucose load not explained by obesity. Int J Obes (Lond) 2011; 35: 595-604.
17. Apolzan JW, Harris RB. Rapid onset and reversal of peripheral and central leptin resistance in rats offered chow, sucrose solution, and lard. Appetite 2013; 60: 65-73.
18. Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschop MH, Schwartz MW. Obesity is associated with hypothalamic injury in rodents and humans. J Clin Invest 2012; 122: 153-162.
19. Chandrasekharan B, Jeppsson S, Pienkowski S, Belsham DD, Sitaraman SV, Merlin D, Kokkotou E, Nusrat A, Tansey MG, Srinivasan S. Tumor necrosis factor-neuropeptide y cross talk regulates inflammation, epithelial barrier functions, and colonic motility. Inflamm Bowel Dis 2013; 19: 2535-2546.
20. Densmore VS, Morton NM, Mullins JJ, Seckl JR. 11 beta-hydroxysteroid dehydrogenase type 1 induction in the arcuate nucleus by high-fat feeding: a novel constraint to hyperphagia? Endocrinology 2006; 147: 4486-4495.
21. Archer ZA, Rayner DV, Duncan JS, Bell LM, Mercer JG. Introduction of a high-energy diet acutely up-regulates hypothalamic cocaine and amphetamine-regulated transcript, Mc4R and brown adipose tissue uncoupling protein-1 gene expression in male Sprague-Dawley rats. J Neuroendocrinol 2005; 17: 10-17.
22. Ziotopoulou M, Mantzoros CS, Hileman SM, Flier JS. Differential expression of hypothalamic neuropeptides in the early phase of diet-induced obesity in mice. Am J Physiol Endocrinol Metab 2000; 279: E838-E845.
23. Kalra PS, Dube MG, Xu B, Kalra SP. Increased receptor sensitivity to neuropeptide Y in the hypothalamus may underlie transient hyperphagia and body weight gain. Regul Pept 1997; 72: 121-130.
24. Widdowson PS, Upton R, Henderson L, Buckingham R, Wilson S, Williams G. Reciprocal regional changes in brain NPY receptor density during dietary restriction and dietary-induced obesity in the rat. Brain Res 1997; 774: 1-10.
25. Schaffhauser AO, Madiehe AM, Braymer HD, Bray GA, York DA. Effects of a high-fat diet and strain on hypothalamic gene expression in rats. Obes Res 2002; 10: 1188-1196.
26. Kalra PS, Dube MG, Xu B, Farmerie WG, Kalra SP. Neuropeptide Y (NPY) Y1 receptor mRNA is upregulated in association with transient hyperphagia and body weight gain: evidence for a hypothalamic site for concurrent development of leptin resistance. J Neuroendocrinol 1998; 10: 43-49.
27. Symeonides SN, Morris MJ, Bournat JC, Allen JM. Leptin regulation of expression of neuropeptide Y and its receptor. Biochem Soc Trans 1998; 26: S203.
28. Hansen MJ, Ball MJ, Morris MJ. Enhanced inhibitory feeding response to alpha-melanocyte stimulating hormone in the diet-induced obese rat. Brain Res 2001; 892: 130-137.
29. Billington CJ, Briggs JE, Harker S, Grace M, Levine AS. Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism. Am J Physiol 1994; 266: R1765-R1770.
30. Schick RR, Schusdziarra V, Nussbaumer C, Classen M. Neuropeptide Y and food intake in fasted rats: effect of naloxone and site of action. Brain Res 1991; 552: 232-239.
31. Morley JE, Levine AS, Gosnell BA, Kneip J, Grace M. Effect of neuropeptide Y on ingestive behaviors in the rat. Am J Physiol 1987; 252: R599-R609.
32. Marks JL, Waite K, Davies L. Intracerebroventricular neuropeptide Y produces hyperinsulinemia in the presence and absence of food. Physiol Behav 1996; 60: 685-692.
33. Parikh R, Marks JL. Metabolic and orexigenic effects of intracerebroventricular neuropeptide Y are attenuated by food deprivation. J Neuroendocrinol 1997; 9: 789-795.
34. Clark JT, Kalra PS, Crowley WR, Kalra SP. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 1984; 115: 427-429.
35. Stanley BG, Daniel DR, Chin AS, Leibowitz SF. Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion. Peptides 1985; 6: 1205-1211.
36. Smith BK, Berthoud HR, York DA, Bray GA. Differential effects of baseline macronutrient preferences on macronutrient selection after galanin, NPY, and an overnight fast. Peptides 1997; 18: 207-211.
37. Stanley BG, Anderson KC, Grayson MH, Leibowitz SF. Repeated hypothalamic stimulation with neuropeptide Y increases daily carbohydrate and fat intake and body weight gain in female rats. Physiol Behav 1989; 46: 173-177.
38. Beck B, Stricker-Krongrad A, Nicolas JP, Burlet C. Chronic and continuous intracerebroventricular infusion of neuropeptide Y in Long-Evans rats mimics the feeding behaviour of obese Zucker rats. Int J Obes Relat Metab Disord 1992; 16: 295-302.
39. Castonguay TW, Hartman WJ, Fitzpatrick EA, Stern JS. Dietary self-selection and the Zucker rat. J Nutr 1982; 112: 796-800.
40. Zhang M, Gosnell BA, Kelley AE. Intake of high-fat food is selectively enhanced by mu opioid receptor stimulation within the nucleus accumbens. J Pharmacol Exp Ther 1998; 285: 908-914.
41. Wolak ML, DeJoseph MR, Cator AD, Mokashi AS, Brownfield MS, Urban JH. Comparative distribution of neuropeptide Y Y1 and Y5 receptors in the rat brain by using immunohistochemistry. J Comp Neurol 2003; 464: 285-311.
42. Giraudo SQ, Grace MK, Billington CJ, Levine AS. Differential effects of neuropeptide Y and the mu-agonist DAMGO on 'palatability' vs. 'energy'. Brain Res 1999; 834: 160-163.
43. Beck B, Burlet A, Bazin R, Nicolas JP, Burlet C. Elevated neuropeptide Y in the arcuate nucleus of young obese Zucker rats may contribute to the development of their overeating. J Nutr 1993; 123: 1168-1172.
44. Wilding JP, Gilbey SG, Bailey CJ, Batt RA, Williams G, Ghatei MA, Bloom SR. Increased neuropeptide-Y messenger ribonucleic acid (mRNA) and decreased neurotensin mRNA in the hypothalamus of the obese (ob/ob) mouse. Endocrinology 1993; 132: 1939-1944.