The inhibitor of calcium/calmodulin-dependent protein kinase II KN93 attenuates bone cancer pain via inhibition of KIF17/NR2B trafficking in mice

Pharmacology Biochemistry and Behavior

Volumn 124, Issue , 2014, Pages 19-26

  Liu, Yue ^a   Liang, Ying ^a   Hou, Bailing ^a   Liu, Ming ^a   Yang, Xuli ^a   Liu, Chenglong ^a   Zhang, Juan ^a   Zhang, Wei ^a   Ma, Zhengliang ^a   Gu, Xiaoping ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Bone cancer pain; Calcium calmodulin dependent protein kinase II; KN93; N methyl d aspartate receptor; N methyl d aspartate receptor 2B subunit

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; KIF17 PROTEIN; KINESIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; UNCLASSIFIED DRUG; BENZYLAMINE DERIVATIVE; KIF17 PROTEIN, MOUSE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NR2B NMDA RECEPTOR; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

ALLODYNIA; ANALGESIC ACTIVITY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CANCER PAIN; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; FEMUR; MALE; MOUSE; NONHUMAN; OSTEOSARCOMA; OSTEOSARCOMA CELL; PAIN ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE TUMOR; C3H MOUSE; COMPLICATION; INTRASPINAL DRUG ADMINISTRATION; METABOLISM; PAIN; TUMOR CELL LINE;

ANIMALS; BENZYLAMINES; BONE NEOPLASMS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL LINE, TUMOR; INJECTIONS, SPINAL; KINESIN; MICE; MICE, INBRED C3H; PAIN; PROTEIN KINASE INHIBITORS; PROTEIN TRANSPORT; RECEPTORS, N-METHYL-D-ASPARTATE; SULFONAMIDES;

EID: 84901398873     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2014.05.003     Document Type: Article

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