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Coleman RE. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 2006; 12:6243s-6249s. This is an excellent review of the natural history of metastatic bone disease, giving particular attention to skeletal complications.
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Goblirsch MJ, Zwolak PP, Clohisy DR. Biology of bone cancer pain. Clin Cancer Res 2006; 12:6231s-6235s. The authors describe, in a very detailed manner, the pathophysiology of bone cancer pain.
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Goblirsch MJ, Zwolak PP, Clohisy DR. Biology of bone cancer pain. Clin Cancer Res 2006; 12:6231s-6235s. The authors describe, in a very detailed manner, the pathophysiology of bone cancer pain.
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4
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Malignant bone pain: Pathophysiology and treatments
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Ripamonti, C.1
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Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs. inflammatory pain
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Luger NM, Sabino M, Schwei MJ, et al. Efficacy of systemic morphine suggests a fundamental difference in the mechanisms that generate bone cancer vs. inflammatory pain. Pain 2002; 99:397-406.
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Luger, N.M.1
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Finniss, D.G.1
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Slatkin N. Cancer-related pain and its pharmacologic management in the patient with bone metastasis. J Support Oncol 2006; 4 (Suppl 1):15-21. This paper provides a comprhensive analysis of pharmacological management in patients with painful bone metastases.
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Slatkin N. Cancer-related pain and its pharmacologic management in the patient with bone metastasis. J Support Oncol 2006; 4 (Suppl 1):15-21. This paper provides a comprhensive analysis of pharmacological management in patients with painful bone metastases.
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10
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An interesting review about treatment options in metastatic bone pain is presented
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O'Toole GC, Boland P. Metastatic bone cancer pain: etiology and treatment options. Curr Pain Headache Rep 2006; 10:288-292. An interesting review about treatment options in metastatic bone pain is presented.
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O'Toole, G.C.1
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A complete and updated review of radiotherapy in the treatment of bone metastases is presented
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Lin, A.1
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24
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33645388855
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The author provides a comprehensive review outlining the role of radiation medicine in the palliation and supportive care of metastatic bone disease
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Janjan N. Palliation and supportive care in radiation medicine. Hematol Oncol Clin North Am 2006; 20:187-211. The author provides a comprehensive review outlining the role of radiation medicine in the palliation and supportive care of metastatic bone disease.
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Janjan, N.1
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25
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33750444930
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The role of external beam radiotherapy in the management of bone metastases
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The authors provide an outstanding meta-analysis on use of radiotherapy in the management of bone metastases. It is of particular interest for clinicians because it is an evidence-based review
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Agarawal JP, Swangsilpa T, van der Linden Y, et al. The role of external beam radiotherapy in the management of bone metastases. Clin Oncol (R Coll Radiol) 2006; 18:747-760. The authors provide an outstanding meta-analysis on use of radiotherapy in the management of bone metastases. It is of particular interest for clinicians because it is an evidence-based review.
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Clin Oncol (R Coll Radiol)
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Agarawal, J.P.1
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Mercadante S. Scoring the effect of radiotherapy for painful bone metastases. Support Care Cancer 2006; 14:967-969.
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27
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33746449278
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This interesting paper underscores the impact of radiotherapy on quality of life in patients with painful bone metastases
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Wu JS, Monk G, Clark T, et al. Palliative radiotherapy improves pain and reduces functional interference in patients with painful bone metastases: a quality assurance study. Clin Oncol (R Coll Radiol) 2006; 18:539-544. This interesting paper underscores the impact of radiotherapy on quality of life in patients with painful bone metastases.
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Clin Oncol (R Coll Radiol)
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Wu, J.S.1
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28
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Loblaw DA, Wu JS, Kirkbride P, et al. Pain flare in patients with bone metastases after palliative radiotherapy-a nested randomized control trial. Support Care Cancer 2006 [Epub ahead of print].
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Loblaw DA, Wu JS, Kirkbride P, et al. Pain flare in patients with bone metastases after palliative radiotherapy-a nested randomized control trial. Support Care Cancer 2006 [Epub ahead of print].
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30
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Evaluation of quality of radiotherapy randomized trials for painful metastases
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31
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3843127661
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33
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33746216868
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Prospective randomised multicenter trial on single fraction radiotherapy (8 Gy x 1) versus multiple fractions (3 Gy x 10) in the treatment of painful bone metastases
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This is one of the most important studies in this field
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Kaasa S, Brenne E, Lund JA, et al. Prospective randomised multicenter trial on single fraction radiotherapy (8 Gy x 1) versus multiple fractions (3 Gy x 10) in the treatment of painful bone metastases. Radiother Oncol 2006; 79:278-284. This is one of the most important studies in this field.
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Radiother Oncol
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Kaasa, S.1
Brenne, E.2
Lund, J.A.3
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34
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33645986651
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Patients with a favourable prognosis are equally palliated with single and multiple fraction radiotherapy: Results on survival in the Dutch Bone Metastasis Study
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Another critical study on this important issue is presented
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van der Linden YM, Steenland E, van Houwelingen HC, et al. Patients with a favourable prognosis are equally palliated with single and multiple fraction radiotherapy: results on survival in the Dutch Bone Metastasis Study. Radiother Oncol 2006; 78:245-253. Another critical study on this important issue is presented.
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van der Linden, Y.M.1
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35
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31644437065
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Chow E, Hoskin PJ, Wu J, et al. A phase III international randomised trial comparing single with multiple fractions for re-irradiation of painful bone metastases: National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) SC 20. Clin Oncol (R Coll Radiol) 2006; 18:125-128. This is a well conducted trial comparing two schedules of radiotherapy in the palliation of bone metastases.
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Chow E, Hoskin PJ, Wu J, et al. A phase III international randomised trial comparing single with multiple fractions for re-irradiation of painful bone metastases: National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) SC 20. Clin Oncol (R Coll Radiol) 2006; 18:125-128. This is a well conducted trial comparing two schedules of radiotherapy in the palliation of bone metastases.
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37
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34250001092
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Outcome after radiotherapy alone for metastatic spinal cord compression in patients with oligometastases
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Rades D, Veninga T, Stalpers LJ, et al. Outcome after radiotherapy alone for metastatic spinal cord compression in patients with oligometastases. J Clin Oncol 2007; 25:50-56.
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41
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33646396747
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Clinical applications of newer radionuclide therapies
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An updated review about recent advances in the applications of newer radioisotopes is presented
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Brans B, Linden O, Giammarile F, et al. Clinical applications of newer radionuclide therapies. Eur J Cancer 2006; 42:994-1003. An updated review about recent advances in the applications of newer radioisotopes is presented.
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Brans, B.1
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42
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(186)ReHEDP in the palliation of painful bone metastases from cancers other than prostate and breast. Q
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Finlay, I.G.1
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33846703339
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Sartor O, Reid RH, Bushnell DL, et al. Safety and efficacy of repeat administration of Samarium Sm-153 lexidronam to patients with metastatic bone pain. Cancer 2006; 109:637-643.
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Ripamonti C, Fagnoni E, Campa T, et al. Incident pain and analgesic consumption decrease after samarium infusion: a pilot study. Support Care Cancer 2006 [Epub ahead of print].
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46
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33745827420
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Serum hemoglobin levels predict response to strontium-89 and rhenium-186-HEDP radionuclide treatment for painful osseous metastases in prostate cancer
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Van der Poel HG, Antonini N, Hoefnagel CA, et al. Serum hemoglobin levels predict response to strontium-89 and rhenium-186-HEDP radionuclide treatment for painful osseous metastases in prostate cancer. Urol Int 2006; 77:50-56.
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Van der Poel, H.G.1
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47
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18044378963
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Palliation of bone pain in prostate cancer using chemotherapy and strontium-89. A randomized phase II study
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Nilsson S, Strang P, Ginman C, et al. Palliation of bone pain in prostate cancer using chemotherapy and strontium-89. A randomized phase II study. J Pain Symptom Manage 2005; 29:352-357.
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Nilsson, S.1
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48
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32944474117
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Therapy tolerance in selected patients with androgen-independent prostate cancer following strontium-89 combined with chemotherapy
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Tu SM, Kim J, Pagliaro LC, et al. Therapy tolerance in selected patients with androgen-independent prostate cancer following strontium-89 combined with chemotherapy. J Clin Oncol 2005; 23:7904-7910.
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Tu, S.M.1
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49
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33744945763
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Storto G, Klain M, Paone G, et al. Combined therapy of Sr-89 and zoledronic acid in patients with painful bone metastases. Bone 2006; 39:35-41. This is an interesting phase II trial of the combination of a radionuclide with a thirdgeneration bisphosphonate.
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Storto G, Klain M, Paone G, et al. Combined therapy of Sr-89 and zoledronic acid in patients with painful bone metastases. Bone 2006; 39:35-41. This is an interesting phase II trial of the combination of a radionuclide with a thirdgeneration bisphosphonate.
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-
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50
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33646547897
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Rhemium-186- monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation
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Ogawa K, Mukai T, Arano Y, et al. Rhemium-186- monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation. Nucl Med Biol 2006; 33:513-520.
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Ogawa, K.1
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51
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Bisphosphonates for treatment and prevention of bone metastases
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Michaelson MD, Smith MR. Bisphosphonates for treatment and prevention of bone metastases. J Clin Oncol 2005; 23:8219-8224.
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Michaelson, M.D.1
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52
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33646444443
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Bisphosphonates for malignancy-related bone disease: Current status, future developments
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An excellent review about the use of bisphosphonates in metastatic bone disease is presented
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Body JJ. Bisphosphonates for malignancy-related bone disease: current status, future developments. Support Care Cancer 2006; 14:408-418. An excellent review about the use of bisphosphonates in metastatic bone disease is presented.
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Support Care Cancer
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Body, J.J.1
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53
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33748165207
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Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer
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This is an interesting analysis of physiopathology in different models of bone cancer
-
Halvorson KG, Sevcik MA, Ghilardi JR, et al. Similarities and differences in tumor growth, skeletal remodeling and pain in an osteolytic and osteoblastic model of bone cancer. Clin J Pain 2006; 22:587-600. This is an interesting analysis of physiopathology in different models of bone cancer.
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Clin J Pain
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Halvorson, K.G.1
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Fulfaro F, Casuccio A, Ticozzi C, et al. The role of bisphosphonates in the treatment of painful metastatic bone disease: a review of phase III trials. Pain 1998; 78:157-169.
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