-
1
-
-
79551667507
-
Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice
-
Amenta A.R., Yilmaz A., Bogdanovich S., McKechnie B.A., Abedi M., Khurana T.S., Fallon J.R. Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:762-767.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 762-767
-
-
Amenta, A.R.1
Yilmaz, A.2
Bogdanovich, S.3
McKechnie, B.A.4
Abedi, M.5
Khurana, T.S.6
Fallon, J.R.7
-
2
-
-
84863164982
-
Biglycan is an extracellular MuSK binding protein important for synapse stability
-
Amenta A.R., Creely H.E., Mercado M.L., Hagiwara H., McKechnie B.A., Lechner B.E., Rossi S.G., Wang Q., Owens R.T., Marrero E., Mei L., Hoch W., Young M.F., McQuillan D.J., Rotundo R.L., Fallon J.R. Biglycan is an extracellular MuSK binding protein important for synapse stability. J. Neurosci. 2012, 32:2324-2334.
-
(2012)
J. Neurosci.
, vol.32
, pp. 2324-2334
-
-
Amenta, A.R.1
Creely, H.E.2
Mercado, M.L.3
Hagiwara, H.4
McKechnie, B.A.5
Lechner, B.E.6
Rossi, S.G.7
Wang, Q.8
Owens, R.T.9
Marrero, E.10
Mei, L.11
Hoch, W.12
Young, M.F.13
McQuillan, D.J.14
Rotundo, R.L.15
Fallon, J.R.16
-
3
-
-
0036744260
-
Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases
-
Ameye L., Young M.F. Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology 2002, 12:107R-116R.
-
(2002)
Glycobiology
, vol.12
-
-
Ameye, L.1
Young, M.F.2
-
4
-
-
0032731755
-
Growth factor regulation of fracture repair
-
Barnes G.L., Kostenuik P.J., Gerstenfeld L.C., Einhorn T.A. Growth factor regulation of fracture repair. J. Bone Miner. Res. 1999, 14:1805-1815.
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1805-1815
-
-
Barnes, G.L.1
Kostenuik, P.J.2
Gerstenfeld, L.C.3
Einhorn, T.A.4
-
5
-
-
80054754245
-
Modulation of canonical Wnt signaling by the extracellular matrix component biglycan
-
Berendsen A.D., Fisher L.W., Kilts T.M., Owens R.T., Robey P.G., Gutkind J.S., Young M.F. Modulation of canonical Wnt signaling by the extracellular matrix component biglycan. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:17022-17027.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 17022-17027
-
-
Berendsen, A.D.1
Fisher, L.W.2
Kilts, T.M.3
Owens, R.T.4
Robey, P.G.5
Gutkind, J.S.6
Young, M.F.7
-
6
-
-
0025110119
-
Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues
-
Bianco P., Fisher L.W., Young M.F., Termine J.D., Robey P.G. Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues. J. Histochem. Cytochem. 1990, 38:1549-1563.
-
(1990)
J. Histochem. Cytochem.
, vol.38
, pp. 1549-1563
-
-
Bianco, P.1
Fisher, L.W.2
Young, M.F.3
Termine, J.D.4
Robey, P.G.5
-
7
-
-
84879905523
-
Decorin causes autophagy in endothelial cells via Peg3
-
Buraschi S., Neill T., Goyal A., Poluzzi C., Smythies J., Owens R.T., Schaefer L., Torres A., Iozzo R.V. Decorin causes autophagy in endothelial cells via Peg3. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:E2582-E2591.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
-
-
Buraschi, S.1
Neill, T.2
Goyal, A.3
Poluzzi, C.4
Smythies, J.5
Owens, R.T.6
Schaefer, L.7
Torres, A.8
Iozzo, R.V.9
-
8
-
-
0036153106
-
Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells
-
Chen X.D., Shi S., Xu T., Robey P.G., Young M.F. Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells. J. Bone Miner. Res. 2002, 17:331-340.
-
(2002)
J. Bone Miner. Res.
, vol.17
, pp. 331-340
-
-
Chen, X.D.1
Shi, S.2
Xu, T.3
Robey, P.G.4
Young, M.F.5
-
9
-
-
0043160417
-
Biglycan-deficient mice have delayed osteogenesis after marrow ablation
-
Chen X.D., Allen M.R., Bloomfield S., Xu T., Young M. Biglycan-deficient mice have delayed osteogenesis after marrow ablation. Calcif. Tissue Int. 2003, 72:577-582.
-
(2003)
Calcif. Tissue Int.
, vol.72
, pp. 577-582
-
-
Chen, X.D.1
Allen, M.R.2
Bloomfield, S.3
Xu, T.4
Young, M.5
-
10
-
-
2942706108
-
The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation
-
Chen X.D., Fisher L.W., Robey P.G., Young M.F. The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation. FASEB J. 2004, 18:948-958.
-
(2004)
FASEB J.
, vol.18
, pp. 948-958
-
-
Chen, X.D.1
Fisher, L.W.2
Robey, P.G.3
Young, M.F.4
-
11
-
-
84872410777
-
VEGF and bone cell signalling: an essential vessel for communication?
-
Clarkin C.E., Gerstenfeld L.C. VEGF and bone cell signalling: an essential vessel for communication?. Cell Biochem. Funct. 2013, 31:1-11.
-
(2013)
Cell Biochem. Funct.
, vol.31
, pp. 1-11
-
-
Clarkin, C.E.1
Gerstenfeld, L.C.2
-
12
-
-
0035991242
-
Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues
-
Corsi A., Xu T., Chen X.D., Boyde A., Liang J., Mankani M., Sommer B., Iozzo R.V., Eichstetter I., Robey P.G., Bianco P., Young M.F. Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues. J. Bone Miner. Res. 2002, 17:1180-1189.
-
(2002)
J. Bone Miner. Res.
, vol.17
, pp. 1180-1189
-
-
Corsi, A.1
Xu, T.2
Chen, X.D.3
Boyde, A.4
Liang, J.5
Mankani, M.6
Sommer, B.7
Iozzo, R.V.8
Eichstetter, I.9
Robey, P.G.10
Bianco, P.11
Young, M.F.12
-
13
-
-
0029119625
-
The effect of exogenous transforming growth factor-beta 2 on healing fractures in the rabbit
-
Critchlow M.A., Bland Y.S., Ashhurst D.E. The effect of exogenous transforming growth factor-beta 2 on healing fractures in the rabbit. Bone 1995, 16:521-527.
-
(1995)
Bone
, vol.16
, pp. 521-527
-
-
Critchlow, M.A.1
Bland, Y.S.2
Ashhurst, D.E.3
-
14
-
-
77950816743
-
Role of the N- and C-terminal fragments of parathyroid-hormone-related protein as putative therapies to improve bone regeneration under high glucocorticoid treatment
-
de Castro L.F., Lozano D., Dapia S., Portal-Nunez S., Caeiro J.R., Gomez-Barrena E., Esbrit P. Role of the N- and C-terminal fragments of parathyroid-hormone-related protein as putative therapies to improve bone regeneration under high glucocorticoid treatment. Tissue Eng. A 2010, 16:1157-1168.
-
(2010)
Tissue Eng. A
, vol.16
, pp. 1157-1168
-
-
de Castro, L.F.1
Lozano, D.2
Dapia, S.3
Portal-Nunez, S.4
Caeiro, J.R.5
Gomez-Barrena, E.6
Esbrit, P.7
-
15
-
-
38849188820
-
The effects of RANKL inhibition on fracture healing and bone strength in a mouse model of osteogenesis imperfecta
-
Delos D., Yang X., Ricciardi B.F., Myers E.R., Bostrom M.P., Camacho N.P. The effects of RANKL inhibition on fracture healing and bone strength in a mouse model of osteogenesis imperfecta. J. Orthop. Res. 2008, 26:153-164.
-
(2008)
J. Orthop. Res.
, vol.26
, pp. 153-164
-
-
Delos, D.1
Yang, X.2
Ricciardi, B.F.3
Myers, E.R.4
Bostrom, M.P.5
Camacho, N.P.6
-
16
-
-
0031734171
-
The cell and molecular biology of fracture healing
-
Einhorn T.A. The cell and molecular biology of fracture healing. Clin. Orthop. Relat. Res. 1998, S7-S21.
-
(1998)
Clin. Orthop. Relat. Res.
-
-
Einhorn, T.A.1
-
17
-
-
0020540538
-
Proteoglycans of developing bone
-
Fisher L.W., Termine J.D., Dejter S.W., Whitson S.W., Yanagishita M., Kimura J.H., Hascall V.C., Kleinman H.K., Hassell J.R., Nilsson B. Proteoglycans of developing bone. J. Biol. Chem. 1983, 258:6588-6594.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 6588-6594
-
-
Fisher, L.W.1
Termine, J.D.2
Dejter, S.W.3
Whitson, S.W.4
Yanagishita, M.5
Kimura, J.H.6
Hascall, V.C.7
Kleinman, H.K.8
Hassell, J.R.9
Nilsson, B.10
-
18
-
-
0029382434
-
Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins
-
Fisher L.W., Stubbs J.T., Young M.F. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop. Scand. Suppl. 1995, 266:61-65.
-
(1995)
Acta Orthop. Scand. Suppl.
, vol.266
, pp. 61-65
-
-
Fisher, L.W.1
Stubbs, J.T.2
Young, M.F.3
-
19
-
-
57149110014
-
Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury
-
Hwang J.Y., Johnson P.Y., Braun K.R., Hinek A., Fischer J.W., O'Brien K.D., Starcher B., Clowes A.W., Merrilees M.J., Wight T.N. Retrovirally mediated overexpression of glycosaminoglycan-deficient biglycan in arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointimae after vascular injury. Am. J. Pathol. 2008, 173:1919-1928.
-
(2008)
Am. J. Pathol.
, vol.173
, pp. 1919-1928
-
-
Hwang, J.Y.1
Johnson, P.Y.2
Braun, K.R.3
Hinek, A.4
Fischer, J.W.5
O'Brien, K.D.6
Starcher, B.7
Clowes, A.W.8
Merrilees, M.J.9
Wight, T.N.10
-
20
-
-
84857021943
-
Small leucine-rich proteoglycans
-
Springer, Berlin Keldelberg, R. Mecham (Ed.)
-
Iozzo R.V., Goldoni S., Berendsen A.D., Young M.F. Small leucine-rich proteoglycans. The Extracellular Matrix: An Overview 2011, Springer, Berlin Keldelberg. R. Mecham (Ed.).
-
(2011)
The Extracellular Matrix: An Overview
-
-
Iozzo, R.V.1
Goldoni, S.2
Berendsen, A.D.3
Young, M.F.4
-
21
-
-
0025424823
-
Acidic fibroblast growth factor (aFGF) injection stimulates cartilage enlargement and inhibits cartilage gene expression in rat fracture healing
-
Jingushi S., Heydemann A., Kana S.K., Macey L.R., Bolander M.E. Acidic fibroblast growth factor (aFGF) injection stimulates cartilage enlargement and inhibits cartilage gene expression in rat fracture healing. J. Orthop. Res. 1990, 8:364-371.
-
(1990)
J. Orthop. Res.
, vol.8
, pp. 364-371
-
-
Jingushi, S.1
Heydemann, A.2
Kana, S.K.3
Macey, L.R.4
Bolander, M.E.5
-
22
-
-
78650706502
-
Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing
-
Kawakatsu M., Kanno S., Gui T., Gai Z., Itoh S., Tanishima H., Oikawa K., Muragaki Y. Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing. Exp. Mol. Pathol. 2011, 90:107-115.
-
(2011)
Exp. Mol. Pathol.
, vol.90
, pp. 107-115
-
-
Kawakatsu, M.1
Kanno, S.2
Gui, T.3
Gai, Z.4
Itoh, S.5
Tanishima, H.6
Oikawa, K.7
Muragaki, Y.8
-
23
-
-
16644376326
-
Characterization of a closed femur fracture model in mice
-
Manigrasso M.B., O'Connor J.P. Characterization of a closed femur fracture model in mice. J. Orthop. Trauma 2004, 18:687-695.
-
(2004)
J. Orthop. Trauma
, vol.18
, pp. 687-695
-
-
Manigrasso, M.B.1
O'Connor, J.P.2
-
24
-
-
0036282775
-
Histological markers for endothelial cells in endogenous and transplanted rodent pancreatic islets
-
Mattsson G., Carlsson P.O., Olausson K., Jansson L. Histological markers for endothelial cells in endogenous and transplanted rodent pancreatic islets. Pancreatology 2002, 2:155-162.
-
(2002)
Pancreatology
, vol.2
, pp. 155-162
-
-
Mattsson, G.1
Carlsson, P.O.2
Olausson, K.3
Jansson, L.4
-
25
-
-
84880176162
-
Fracture healing with alendronate treatment in the Brtl/+ mouse model of osteogenesis imperfecta
-
Meganck J.A., Begun D.L., McElderry J.D., Swick A., Kozloff K.M., Goldstein S.A., Morris M.D., Marini J.C., Caird M.S. Fracture healing with alendronate treatment in the Brtl/+ mouse model of osteogenesis imperfecta. Bone 2013, 56:204-212.
-
(2013)
Bone
, vol.56
, pp. 204-212
-
-
Meganck, J.A.1
Begun, D.L.2
McElderry, J.D.3
Swick, A.4
Kozloff, K.M.5
Goldstein, S.A.6
Morris, M.D.7
Marini, J.C.8
Caird, M.S.9
-
26
-
-
33845666156
-
Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS
-
Mercado M.L., Amenta A.R., Hagiwara H., Rafii M.S., Lechner B.E., Owens R.T., McQuillan D.J., Froehner S.C., Fallon J.R. Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS. FASEB J. 2006, 20:1724-1726.
-
(2006)
FASEB J.
, vol.20
, pp. 1724-1726
-
-
Mercado, M.L.1
Amenta, A.R.2
Hagiwara, H.3
Rafii, M.S.4
Lechner, B.E.5
Owens, R.T.6
McQuillan, D.J.7
Froehner, S.C.8
Fallon, J.R.9
-
27
-
-
58249119459
-
Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function
-
Morgan E.F., Mason Z.D., Chien K.B., Pfeiffer A.J., Barnes G.L., Einhorn T.A., Gerstenfeld L.C. Micro-computed tomography assessment of fracture healing: relationships among callus structure, composition, and mechanical function. Bone 2009, 44:335-344.
-
(2009)
Bone
, vol.44
, pp. 335-344
-
-
Morgan, E.F.1
Mason, Z.D.2
Chien, K.B.3
Pfeiffer, A.J.4
Barnes, G.L.5
Einhorn, T.A.6
Gerstenfeld, L.C.7
-
28
-
-
0031781483
-
Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture
-
Nakamura T., Hara Y., Tagawa M., Tamura M., Yuge T., Fukuda H., Nigi H. Recombinant human basic fibroblast growth factor accelerates fracture healing by enhancing callus remodeling in experimental dog tibial fracture. J. Bone Miner. Res. 1998, 13:942-949.
-
(1998)
J. Bone Miner. Res.
, vol.13
, pp. 942-949
-
-
Nakamura, T.1
Hara, Y.2
Tagawa, M.3
Tamura, M.4
Yuge, T.5
Fukuda, H.6
Nigi, H.7
-
29
-
-
84865743796
-
The contribution of the extracellular matrix to the fracture resistance of bone
-
Nyman J.S., Makowski A.J. The contribution of the extracellular matrix to the fracture resistance of bone. Curr. Osteoporos. Rep. 2012, 10:169-177.
-
(2012)
Curr. Osteoporos. Rep.
, vol.10
, pp. 169-177
-
-
Nyman, J.S.1
Makowski, A.J.2
-
30
-
-
84891083715
-
ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro
-
Obika M., Vernon R.B., Gooden M.D., Braun K.R., Chan C.K., Wight T.N. ADAMTS-4 and biglycan are expressed at high levels and co-localize to podosomes during endothelial cell tubulogenesis in vitro. J. Histochem. Cytochem. 2013, 62:34-49.
-
(2013)
J. Histochem. Cytochem.
, vol.62
, pp. 34-49
-
-
Obika, M.1
Vernon, R.B.2
Gooden, M.D.3
Braun, K.R.4
Chan, C.K.5
Wight, T.N.6
-
31
-
-
23644456849
-
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
-
Schaefer L., Babelova A., Kiss E., Hausser H.J., Baliova M., Krzyzankova M., Marsche G., Young M.F., Mihalik D., Gotte M., Malle E., Schaefer R.M., Grone H.J. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J. Clin. Invest. 2005, 115:2223-2233.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2223-2233
-
-
Schaefer, L.1
Babelova, A.2
Kiss, E.3
Hausser, H.J.4
Baliova, M.5
Krzyzankova, M.6
Marsche, G.7
Young, M.F.8
Mihalik, D.9
Gotte, M.10
Malle, E.11
Schaefer, R.M.12
Grone, H.J.13
-
32
-
-
33751506452
-
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
-
Tsuji K., Bandyopadhyay A., Harfe B.D., Cox K., Kakar S., Gerstenfeld L., Einhorn T., Tabin C.J., Rosen V. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat. Genet. 2006, 38:1424-1429.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1424-1429
-
-
Tsuji, K.1
Bandyopadhyay, A.2
Harfe, B.D.3
Cox, K.4
Kakar, S.5
Gerstenfeld, L.6
Einhorn, T.7
Tabin, C.J.8
Rosen, V.9
-
33
-
-
17344364096
-
Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice
-
Xu T., Bianco P., Fisher L.W., Longenecker G., Smith E., Goldstein S., Bonadio J., Boskey A., Heegaard A.M., Sommer B., Satomura K., Dominguez P., Zhao C., Kulkarni A.B., Robey P.G., Young M.F. Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat. Genet. 1998, 20:78-82.
-
(1998)
Nat. Genet.
, vol.20
, pp. 78-82
-
-
Xu, T.1
Bianco, P.2
Fisher, L.W.3
Longenecker, G.4
Smith, E.5
Goldstein, S.6
Bonadio, J.7
Boskey, A.8
Heegaard, A.M.9
Sommer, B.10
Satomura, K.11
Dominguez, P.12
Zhao, C.13
Kulkarni, A.B.14
Robey, P.G.15
Young, M.F.16
-
34
-
-
84865579177
-
Biglycan: a promising new therapeutic for neuromuscular and musculoskeletal diseases
-
Young M.F., Fallon J.R. Biglycan: a promising new therapeutic for neuromuscular and musculoskeletal diseases. Curr. Opin. Genet. Dev. 2012, 22:398-400.
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 398-400
-
-
Young, M.F.1
Fallon, J.R.2
|