-
1
-
-
0029095021
-
Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT
-
Cockerill GW, Bert AG, Ryan GR, Gamble JR, Vadas MA, et al. (1995) Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT. Blood 86: 2689-2698.
-
(1995)
Blood
, vol.86
, pp. 2689-2698
-
-
Cockerill, G.W.1
Bert, A.G.2
Ryan, G.R.3
Gamble, J.R.4
Vadas, M.A.5
-
2
-
-
0037047691
-
Cyclophilin-mediated pathways in the effect of cyclosporin A on endothelial cells: Role of vascular endothelial growth factor
-
DOI 10.1161/01.RES.0000027562.91075.56
-
Alvarez-Arroyo MV, Yague S, Wenger RM, Pereira DS, Jimenez S, et al. (2002) Cyclophilin-mediated pathways in the effect of cyclosporin A on endothelial cells: role of vascular endothelial growth factor. Circ Res 91: 202-209. (Pubitemid 34875674)
-
(2002)
Circulation Research
, vol.91
, Issue.3
, pp. 202-209
-
-
Alvarez-Arroyo, M.V.1
Yague, S.2
Wenger, R.M.3
Pereira, D.S.4
Jimenez, S.5
Gonzalez-Pacheco, F.R.6
Castilla, M.A.7
Deudero, J.J.P.8
Caramelo, C.9
-
3
-
-
0035809312
-
Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: Roles of the nuclear factor of activated T cells and cyclooxygenase 2
-
DOI 10.1084/jem.193.5.607
-
Hernandez GL, Volpert OV, Iniguez MA, Lorenzo E, Martinez-Martinez S, et al. (2001) Selective inhibition of vascular endothelial growth factor-mediated angiogenesis by cyclosporin A: roles of the nuclear factor of activated T cells and cyclooxygenase 2. J Exp Med 193: 607-620. (Pubitemid 32539557)
-
(2001)
Journal of Experimental Medicine
, vol.193
, Issue.5
, pp. 607-620
-
-
Hernandez, G.L.1
Volpert, O.V.2
Iniguez, M.A.3
Lorenzo, E.4
Martinez-Martinez, S.5
Grau, R.6
Fresno, M.7
Redondo, J.M.8
-
4
-
-
0031823067
-
Histamine induces nuclear factor of activated T cell-mediated transcription and cyclosporin A-sensitive interleukin-8 mRNA expression in human umbilical vein endothelial cells
-
Boss V, Wang X, Koppelman LF, Xu K, Murphy TJ (1998) Histamine induces nuclear factor of activated T cell-mediated transcription and cyclosporin A-sensitive interleukin-8 mRNA expression in human umbilical vein endothelial cells. Mol Pharmacol 54: 264-272. (Pubitemid 28368815)
-
(1998)
Molecular Pharmacology
, vol.54
, Issue.2
, pp. 264-272
-
-
Boss, V.1
Wang, X.2
Koppelman, L.F.3
Xu, K.4
Murphy, T.J.5
-
5
-
-
0033019518
-
Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: A role for tissue factor gene expression
-
Armesilla AL, Lorenzo E, Gomez del Arco P, Martinez-Martinez S, Alfranca A, et al. (1999) Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression. Mol Cell Biol 19: 2032-2043. (Pubitemid 29098261)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.3
, pp. 2032-2043
-
-
Armesilla, A.L.1
Lorenzo, E.2
Del, A.P.G.3
Martinez-Martinez, S.4
Alfranca, A.5
Redondo, J.M.6
-
7
-
-
0036156424
-
Cyclooxygenase-2-10 years later
-
Hinz B, Brune K (2002) Cyclooxygenase-2-10 years later. J Pharmacol Exp Ther 300: 367-375.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 367-375
-
-
Hinz, B.1
Brune, K.2
-
8
-
-
34748914299
-
Evolving functions of endothelial cells in inflammation
-
DOI 10.1038/nri2171, PII NRI2171
-
Pober JS, Sessa WC (2007) Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 7: 803-815. (Pubitemid 47480307)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.10
, pp. 803-815
-
-
Pober, J.S.1
Sessa, W.C.2
-
9
-
-
0037405043
-
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
-
DOI 10.1128/MCB.23.9.3173-3185.2003
-
Dryden SC, Nahhas FA, Nowak JE, Goustin AS, Tainsky MA (2003) Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol Cell Biol 23: 3173-3185. (Pubitemid 36459231)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.9
, pp. 3173-3185
-
-
Dryden, S.C.1
Nahhas, F.A.2
Nowak, J.E.3
Goustin, A.-S.4
Tainsky, M.A.5
-
10
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
DOI 10.1038/35065638
-
Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227-230. (Pubitemid 32216597)
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
11
-
-
47849088748
-
Emerging roles of SIRT1 in vascular endothelial homeostasis
-
Potente M, Dimmeler S (2008) Emerging roles of SIRT1 in vascular endothelial homeostasis. Cell Cycle 7: 2117-2122. (Pubitemid 352036236)
-
(2008)
Cell Cycle
, vol.7
, Issue.14
, pp. 2117-2122
-
-
Potente, M.1
Dimmeler, S.2
-
12
-
-
35348980724
-
SIRT1 controls endothelial angiogenic functions during vascular growth
-
DOI 10.1101/gad.435107
-
Potente M, Ghaeni L, Baldessari D, Mostoslavsky R, Rossig L, et al. (2007) SIRT1 controls endothelial angiogenic functions during vascular growth. Genes Dev 21: 2644-2658. (Pubitemid 47607673)
-
(2007)
Genes and Development
, vol.21
, Issue.20
, pp. 2644-2658
-
-
Potente, M.1
Ghaeni, L.2
Baldessari, D.3
Mostoslavsky, R.4
Rossig, L.5
Dequiedt, F.6
Haendeler, J.7
Mione, M.8
Dejana, E.9
Alt, F.W.10
Zeiher, A.M.11
Dimmeler, S.12
-
13
-
-
54149103338
-
Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice
-
Zhang QJ, Wang Z, Chen HZ, Zhou S, Zheng W, et al. (2008) Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice. Cardiovasc Res 80: 191-199.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 191-199
-
-
Zhang, Q.J.1
Wang, Z.2
Chen, H.Z.3
Zhou, S.4
Zheng, W.5
-
14
-
-
80052580047
-
Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia-induced endothelial dysfunction
-
Zhou S, Chen HZ, Wan YZ, Zhang QJ, Wei YS, et al. (2011) Repression of P66Shc expression by SIRT1 contributes to the prevention of hyperglycemia- induced endothelial dysfunction. Circ Res 109: 639-648.
-
(2011)
Circ Res
, vol.109
, pp. 639-648
-
-
Zhou, S.1
Chen, H.Z.2
Wan, Y.Z.3
Zhang, Q.J.4
Wei, Y.S.5
-
15
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
DOI 10.1016/S0092-8674(01)00524-4
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, et al. (2001) Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107: 137-148. (Pubitemid 33035941)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.-I.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
16
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
DOI 10.1016/S0092-8674(01)00527-X
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, et al. (2001) hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107: 149-159. (Pubitemid 33035942)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
17
-
-
12144290563
-
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
-
DOI 10.1126/science.1094637
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, et al. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015. (Pubitemid 38393275)
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsy, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.-L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
18
-
-
77951211562
-
SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages
-
Zhang R, Chen HZ, Liu JJ, Jia YY, Zhang ZQ, et al. (2010) SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages. J Biol Chem 285: 7097-7110.
-
(2010)
J Biol Chem
, vol.285
, pp. 7097-7110
-
-
Zhang, R.1
Chen, H.Z.2
Liu, J.J.3
Jia, Y.Y.4
Zhang, Z.Q.5
-
19
-
-
77957564311
-
SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/-mice
-
Albany NY
-
Stein S, Schafer N, Breitenstein A, Besler C, Winnik S, et al. (2010) SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/-mice. Aging (Albany NY) 2: 353-360.
-
(2010)
Aging
, vol.2
, pp. 353-360
-
-
Stein, S.1
Schafer, N.2
Breitenstein, A.3
Besler, C.4
Winnik, S.5
-
20
-
-
0037474507
-
Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression
-
DOI 10.1016/S0006-291X(02)03020-6
-
Takata T, Ishikawa F (2003) Human Sir2-related protein SIRT1 associates with the bHLH repressors HES1 and HEY2 and is involved in HES1- and HEY2-mediated transcriptional repression. Biochem Biophys Res Commun 301: 250-257. (Pubitemid 36268876)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.301
, Issue.1
, pp. 250-257
-
-
Takata, T.1
Ishikawa, F.2
-
21
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
-
DOI 10.1038/nature02583
-
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, et al. (2004) Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 429: 771-776. (Pubitemid 38833129)
-
(2004)
Nature
, vol.429
, Issue.6993
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
De Oliveira, R.M.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
22
-
-
20644466433
-
NFAT proteins: Key regulators of T-cell development and function
-
Macian F (2005) NFAT proteins: key regulators of T-cell development and function. Nat Rev Immunol 5: 472-484.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 472-484
-
-
Macian, F.1
-
23
-
-
0345218311
-
Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP)
-
DOI 10.1084/jem.187.12.2031
-
Garcia-Rodriguez C, Rao A (1998) Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP). J Exp Med 187: 2031-2036. (Pubitemid 28285572)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.12
, pp. 2031-2036
-
-
Garcia-Rodriguez, C.1
Rao, A.2
-
24
-
-
42149193168
-
A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism involving protein kinase C-theta-mediated up-regulation of the amino-terminal transactivation domain of p300
-
Granja AG, Perkins ND, Revilla Y (2008) A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism involving protein kinase C-theta-mediated up-regulation of the amino-terminal transactivation domain of p300. J Immunol 180: 2429-2442.
-
(2008)
J Immunol
, vol.180
, pp. 2429-2442
-
-
Granja, A.G.1
Perkins, N.D.2
Revilla, Y.3
-
25
-
-
0035971436
-
Partners in transcription: NFAT and AP-1
-
DOI 10.1038/sj.onc.1204386
-
Macian F, Lopez-Rodriguez C, Rao A (2001) Partners in transcription: NFAT and AP-1. Oncogene 20: 2476-2489. (Pubitemid 32531304)
-
(2001)
Oncogene
, vol.20
, Issue.19 REV. ISS. 2
, pp. 2476-2489
-
-
Macian, F.1
Lopez-Rodriguez, C.2
Rao, A.3
-
26
-
-
0034604683
-
An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes
-
DOI 10.1074/jbc.M001381200
-
Iniguez MA, Martinez-Martinez S, Punzon C, Redondo JM, Fresno M (2000) An essential role of the nuclear factor of activated T cells in the regulation of the expression of the cyclooxygenase-2 gene in human T lymphocytes. J Biol Chem 275: 23627-23635. (Pubitemid 30624647)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.31
, pp. 23627-23635
-
-
Iniguez, M.A.1
Martinez-Martinez, S.2
Punzon, C.3
Redondo, M.J.4
Fresno, M.5
-
27
-
-
0029595394
-
Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells
-
Yamamoto K, Arakawa T, Ueda N, Yamamoto S (1995) Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells. J Biol Chem 270: 31315-31320.
-
(1995)
J Biol Chem
, vol.270
, pp. 31315-31320
-
-
Yamamoto, K.1
Arakawa, T.2
Ueda, N.3
Yamamoto, S.4
-
28
-
-
0028226265
-
Characterization of the human gene (PTGS2) encoding prostaglandin- endoperoxide synthase 2
-
Kosaka T, Miyata A, Ihara H, Hara S, Sugimoto T, et al. (1994) Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur J Biochem 221: 889-897. (Pubitemid 24146188)
-
(1994)
European Journal of Biochemistry
, vol.221
, Issue.3
, pp. 889-897
-
-
Kosaka, T.1
Miyata, A.2
Ihara, H.3
Hara, S.4
Sugimoto, T.5
Takeda, O.6
Takahashi, E.7
Tanabe, T.8
-
29
-
-
0034644473
-
Signaling to chromatin through histone modifications
-
Cheung P, Allis CD, Sassone-Corsi P (2000) Signaling to chromatin through histone modifications. Cell 103: 263-271.
-
(2000)
Cell
, vol.103
, pp. 263-271
-
-
Cheung, P.1
Allis, C.D.2
Sassone-Corsi, P.3
-
30
-
-
0034610814
-
The language of covalent histone modifications
-
DOI 10.1038/47412
-
Strahl BD, Allis CD (2000) The language of covalent histone modifications. Nature 403: 41-45. (Pubitemid 30038513)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
31
-
-
0030973579
-
Transcription factors of the NFAT family: Regulation and function
-
DOI 10.1146/annurev.immunol.15.1.707
-
Rao A, Luo C, Hogan PG (1997) Transcription factors of the NFAT family: regulation and function. Annu Rev Immunol 15: 707-747. (Pubitemid 27169297)
-
(1997)
Annual Review of Immunology
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
32
-
-
78649738291
-
SIRT2 regulates NF-kappaB dependent gene expression through deacetylation of p65 Lys310
-
Rothgiesser KM, Erener S, Waibel S, Luscher B, Hottiger MO (2010) SIRT2 regulates NF-kappaB dependent gene expression through deacetylation of p65 Lys310. J Cell Sci 123: 4251-4258.
-
(2010)
J Cell Sci
, vol.123
, pp. 4251-4258
-
-
Rothgiesser, K.M.1
Erener, S.2
Waibel, S.3
Luscher, B.4
Hottiger, M.O.5
-
33
-
-
84872314486
-
SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells
-
Jia Y, Gao P, Chen H, Wan Y, Zhang R, et al. (2013) SIRT1 suppresses PMA and ionomycin-induced ICAM-1 expression in endothelial cells. Sci China Life Sci 56: 19-25.
-
(2013)
Sci China Life Sci
, vol.56
, pp. 19-25
-
-
Jia, Y.1
Gao, P.2
Chen, H.3
Wan, Y.4
Zhang, R.5
-
34
-
-
67650659852
-
Antioxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: Role of circulating factors and SIRT1
-
Csiszar A, Labinskyy N, Jimenez R, Pinto JT, Ballabh P, et al. (2009) Antioxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev 130: 518-527.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 518-527
-
-
Csiszar, A.1
Labinskyy, N.2
Jimenez, R.3
Pinto, J.T.4
Ballabh, P.5
-
35
-
-
0035967887
-
2+/calcineurin and NFATc3/c4 pattern the developing vasculature
-
DOI 10.1016/S0092-8674(01)00396-8
-
Graef IA, Chen F, Chen L, Kuo A, Crabtree GR (2001) Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell 105: 863-875. (Pubitemid 32635088)
-
(2001)
Cell
, vol.105
, Issue.7
, pp. 863-875
-
-
Graef, I.A.1
Chen, F.2
Chen, L.3
Kuo, A.4
Crabtree, G.R.5
-
36
-
-
1642355137
-
Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: Role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase
-
DOI 10.1074/jbc.M312920200
-
Gonzalez Bosc LV, Wilkerson MK, Bradley KN, Eckman DM, Hill-Eubanks DC, et al. (2004) Intraluminal pressure is a stimulus for NFATc3 nuclear accumulation: role of calcium, endothelium-derived nitric oxide, and cGMP-dependent protein kinase. J Biol Chem 279: 10702-10709. (Pubitemid 38372683)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 10702-10709
-
-
Gonzalez, B.L.V.1
Wilkerson, M.K.2
Bradley, K.N.3
Eckman, D.M.4
Hill-Eubanks, D.C.5
Nelson, M.T.6
-
37
-
-
8744315615
-
NFATc3 regulates Kv2.1 expression in arterial smooth muscle
-
DOI 10.1074/jbc.M408789200
-
Amberg GC, Rossow CF, Navedo MF, Santana LF (2004) NFATc3 regulates Kv2.1 expression in arterial smooth muscle. J Biol Chem 279: 47326-47334. (Pubitemid 39518389)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.45
, pp. 47326-47334
-
-
Amberg, G.C.1
Rossow, C.F.2
Navedo, M.F.3
Santana, L.F.4
-
38
-
-
58849158388
-
How does SIRT1 affect metabolism, senescence and cancer?
-
Brooks CL, Gu W (2009) How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer 9: 123-128.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 123-128
-
-
Brooks, C.L.1
Gu, W.2
-
39
-
-
1442330508
-
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo
-
DOI 10.1073/pnas.0308762101
-
Luo J, Li M, Tang Y, Laszkowska M, Roeder RG, et al. (2004) Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. Proc Natl Acad Sci U S A 101: 2259-2264. (Pubitemid 38269299)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.8
, pp. 2259-2264
-
-
Luo, J.1
Li, M.2
Tang, Y.3
Laszkowska, M.4
Roeder, R.G.5
Gu, W.6
-
40
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
DOI 10.1038/sj.emboj.7600244
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, et al. (2004) Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23: 2369-2380. (Pubitemid 38954844)
-
(2004)
EMBO Journal
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
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