Streptozotocin-induced diabetes increases the interaction of Bad/Bcl-XL and decreases the binding of pBad/14-3-3 in rat testis

Life Sciences

Volumn 81, Issue 13, 2007, Pages 1079-1084

  Koh, Phil Ok ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Apoptosis; Bcl 2 family protein; Rat testis; Streptozotocin induced diabetes

Indexed keywords

PROTEIN BAD; PROTEIN BCL XL; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; HISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; NONHUMAN; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT; SEXUAL DYSFUNCTION; STREPTOZOCIN DIABETES; TESTIS; WESTERN BLOTTING;

14-3-3 PROTEINS; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; BCL-X PROTEIN; CELL DEATH; DIABETES MELLITUS, EXPERIMENTAL; GENE EXPRESSION REGULATION; GERM CELLS; INHIBITOR OF APOPTOSIS PROTEINS; MALE; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; TESTIS;

RATTUS;

EID: 34548692768     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.08.017     Document Type: Article

References (26)

1. Baccetti B., La Marca A., Piomboni P., Capitani S., Bruni E., Petraglia F., and De Leo V. Insulin-dependent diabetes in men is associated with hypothalamo-pituitary derangement and with impairment in semen quality. Human Reproduction 17 10 (2002) 2673-2677
2. Cai L., Chen S., Evans T., Deng D.X., Mukherjee K., and Chakrabarti S. Apoptotic germ-cell death and testicular damage in experimental diabetes: prevention by endothelin antagonism. Urological Research 28 5 (2000) 342-347
3. Calvo J.C., Baranao J.L., Tesone M., and Charreau E.H. Hypothalamic-hypophyseal-gonadal axis in the streptozotocin-induced diabetic male rat. Journal of Steroid Biochemistry and Molecular Biology 20 3 (1984) 769-772
4. Datta S.R., Brunet A., and Greenberg M.E. Cellular survival: a play in three Akts. Genes and Development 13 22 (1999) 2905-2927
5. Ficher M., Zuckerman M., Fishkin R.E., Goldman A., Neeb M., Fink P.J., Cohen S.N., Jacobs J.A., and Weisberg M. Do endocrines play an etiological role in diabetic and nondiabetic sexual dysfunctions?. Journal of Andrology 5 1 (1984) 8-16
6. Henshall D.C., Araki T., Schindler C.K., Lan J.Q., Teikoter K.L., Taki W., and Simon R.P. Activation of Bcl-2-associated death protein and counter-response of Akt within cell populations during seizure-induced neuronal death. Journal of Neuroscience 22 19 (2002) 8458-8465
7. Hu J.H., Jiang J., Ma Y.H., Yang N., Zhang M.H., Wu M., Fei J., and Guo L.H. Enhancement of germ cell apoptosis induced by ethanol in transgenic mice overexpressing Fas Ligand. Cell Reseach. 13 5 (2003) 361-367
8. Jesmin S., Zaedi S., Yamaguchi N., Maeda S., Yamaguchi I., Goto K., and Miyauchi T. Effects of dual endothelin receptor antagonist on antiapoptotic marker Bcl-2 expression in streptozotocin-induced diabetic rats. Experimental Biology and Medicine 231 6 (2006) 1034-1039
9. Koh P.O., Sung J.H., Won C.K., Cho J.H., Moon J.G., Park O.S., and Kim M.O. Streptozotocin-induced diabetes increases apoptosis through JNK phosphorylation and Bax activation in rat testes. Journal of Veterinary Medical Science 69 9 (2007) 877-880
10. Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Medicine 3 6 (1997) 614-620
11. Kuhn-Velten N., Schermer R., and Staib W. Effect of streptozotocin-induced hyperglycaemia on androgen-binding protein in rat testis and epididymis. Diabetologia 26 4 (1984) 300-303
12. Lu X., Kambe F., Cao X., Yoshida T., Ohmori S., Murakami K., Kaji T., Ishii T., Zadworny D., and Seo H. DHCR24-knockout embryonic fibroblasts are susceptible to serum withdrawal-induced apoptosis because of dysfunction of caveolae and insulin-Akt-Bad signaling. Endocrinology 147 6 (2006) 3123-3132
13. Murray F.T., Cameron D.F., and Orth J.M. Gonadal dysfunction in the spontaneously diabetic BB rat. Metabolism 32 7 (1983) 141-147
14. Nomura M., Shimizu S., Sugiyama T., Narita M., Ito T., Matsuda H., and Tsujimoto Y. 14-3-3 interacts directly with and negatively regulates pro-apoptotic Bax. Journal of Biological Chemistry 278 3 (2003) 2058-2065
15. Oltvai Z.N., Milliman C.L., and Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74 4 (1993) 609-619
16. Pampfer S., Cordi S., Vanderheyden I., Van Der Smissen P., Courtoy P.J., Van Cauwenberge A., Alexandre H., Donnay I., and De Hertogh R. Expression and role of Bcl-2 in rat blastocysts exposed to high D-glucose. Diabetes 50 1 (2001) 143-149
17. Sainio-Pollanen S., Henriksen K., Parvinen M., Simell O., and Pollanen P. Stage-specific degeneration of germ cells in the seminiferous tubules of non-obese diabetic mice. International Journal of Andrology 20 4 (1997) 243-253
18. Scarano W.P., Messias A.G., Oliva S.U., Klinefelter G.R., and Kempinas W.G. Sexual behaviour, sperm quantity and quality after short-term streptozotocin-induced hyperglycaemia in rats. International Journal of Andrology 29 4 (2006) 482-488
19. Seethalakshmi L., Menon M., and Diamond D. The effect of streptozotocin-induced diabetes on the neuroendocrine-male reproductive tract axis of the adult rat. Journal of Urology 138 1 (1987) 190-194
20. Sexton W.J., and Jarow J.P. Effect of diabetes mellitus upon male reproductive function. Urology 49 4 (1997) 508-513
21. Sinha Hikim A.P., and Swerdloff R.S. Hormonal and genetic control of germ cell apoptosis in the testis. Reviews of Reproduction 4 1 (1999) 38-47
22. Steger R.W., Amador A., Lam E., Rathert J., Weis J., and Smith M.S. Streptozotocin-induced deficits in sex behavior and neuroendocrine function in male rats. Endocrinology 124 4 (1989) 1737-1743
23. Yang E., Zha J., Jockel J., Boise L.H., Thompson C.B., and Korsmeyer S.J. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80 2 (1995) 285-291
24. Yang J., Liu X., Bhalla K., Kim C.N., Ibrado A.M., M Cai J., Peng T.I., Jones D.P., and Wang X. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275 5303 (1997) 1129-1132
25. Zha J., Harada H., Yang E., Jockel J., and Korsmeyer S.J. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-x(L). Cell 87 4 (1996) 619-628
26. Zha H., Aime-Sempe C., Sato T., and Reed J.C. Proapoptotic protein Bax heterodimerizes with Bcl-2 and homodimerizes with Bax via a novel domain (BH3) distinct from BH1 and BH2. Journal of Biological Chemistry 271 13 (1996) 7440-7444