Potent adjuvant effects of novel NKT stimulatory glycolipids on hemagglutinin based DNA vaccine for H5N1 influenza virus

Antiviral Research

Volumn 107, Issue 1, 2014, Pages 110-118

  Hung, Jung Tung ^a,e   Tsai, Yi Chieh ^a   Lin, Wen Der ^a,b   Jan, Jia Tsrong ^a   Lin, Kun Hsien ^a   Huang, Jing Rong ^a,c   Cheng, Jing Yan ^a,b   Chen, Ming Wei ^a,d   Wong, Chi Huey ^d   Yu, Alice L ^a,e  

^a GENOMICS RESEARCH CENTER   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

^d ROCKEFELLER UNIVERSITY   (United States)

^e CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Cross protection; Glycolipid; Influenza vaccine; iNKT

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; C34 VACCINE; DNA VACCINE; GAMMA INTERFERON; GRANULOCYTE COLONY STIMULATING FACTOR; HEMAGGLUTININ BASED DNA VACCINE; IMMUNOGLOBULIN G; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; GLYCOLIPID; HEMAGGLUTININ, AVIAN INFLUENZA A VIRUS; IMMUNOLOGICAL ADJUVANT; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CELLULAR IMMUNITY; CHEMOTAXIS; CONSENSUS; CONTROLLED STUDY; DNA SEQUENCE; DRUG DOSE REDUCTION; DRUG EFFICACY; ELECTROPORATION; FEMALE; GENETIC REASSORTMENT; HUMORAL IMMUNITY; INFLUENZA; INFLUENZA VACCINATION; INFLUENZA VIRUS A H5N1; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SINGLE DRUG DOSE; SURVIVAL; SURVIVAL RATE; VACCINE PRODUCTION; VIRION; VIRUS NEUTRALIZATION; VIRUS PARTICLE; VIRUS TITRATION; ANIMAL; BAGG ALBINO MOUSE; BLOOD; DISEASE MODEL; DRUG EFFECTS; GENETICS; IMMUNOLOGY; INTRAMUSCULAR DRUG ADMINISTRATION; NATURAL KILLER CELL; ORTHOMYXOVIRIDAE INFECTIONS; SECRETION (PROCESS);

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; ELECTROPORATION; FEMALE; GLYCOLIPIDS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA VACCINES; INJECTIONS, INTRAMUSCULAR; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; SURVIVAL ANALYSIS; VACCINES, DNA;

EID: 84901372468     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.04.007     Document Type: Article

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