Effects of dimethyl sulfoxide in cholesterol-containing lipid membranes: A comparative study of experiments in silico and with cells

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  de Ménorval, Marie Amélie ^a,b,c   Mir, Lluis M ^a,b,c   Fernández, M Laura ^d,e   Reigada, Ramon ^f  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^e Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^f UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; DIMETHYL SULFOXIDE; IODIDE; WATER;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL ASSAY; CELL MEMBRANE PERMEABILITY; COMPARATIVE STUDY; COMPUTER MODEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FIBROBLAST; LIPID BILAYER; LIPID MEMBRANE; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; NONHUMAN; PREDICTION; STRUCTURE ANALYSIS;

ANIMALS; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CHOLESTEROL; COMPUTATIONAL BIOLOGY; CRICETINAE; DIMETHYL SULFOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; LIPID BILAYERS; MOLECULAR CONFORMATION; MOLECULAR DYNAMICS SIMULATION; POROSITY;

EID: 84864346804     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041733     Document Type: Article

References (42)

1. Rall WF, Fahy GM, (1985) Ice-free cryopreservation of Mouse embryos at -196°C by vitrification. Nature 313: 573-575.
2. Amodeo P, Motta A, Picone D, Saviano G, Tancredi T, et al. (1991) Viscosity as a conformational sieve. NOE of linear peptides in cryoprotective mixtures. J. Magn. Reson. 95, 201-207.
3. Ahkong QF, Fisher D, Tampion W, Lucy JA, (1975) Mechanisms of cell fusion. Nature 253: 194-195.
4. Kligman AM, (1965) Topical pharmacology and toxicology of dimethylsulfoxide. J Am Med Assoc. 193: 796-804.
5. Tristam-Nagle S, Moore T, Petrache I, Tagle JF, (1998) DMSO produces a new subgel phase in DPPC: DSC and X-ray diffraction study. Biochim. Biophys. Acta 1369: 19-33.
6. Yu ZW, Quinn PJ, (2000) The effect of dimethyl sulphoxide on the structure and phase behavior of palmitoleoylphosphatidylethanolamine. Biochim. Biophys. Acta 1509: 440-450.
7. Sum AK, de Pablo JJ, (2003) Molecular simulation study on the influence of dimethylsulfoxide on the structure of phospholipid bilayers. Biophys. J. 85: 3636-3645.
8. Notman R, den Otter WK, Noro MG, Briels WJ, Anwar J, (2007) The permeability enhancing mechanism of DMSO in ceramide bilayers simulated by molecular dynamics. Biophys. J. 93: 2056-2068.
9. Gurtovenko AA, Anwar J, (2007) Modulating the structure and properties of cell membranes: the molecular mechanism of action of dimethyl sulfoxide. J. Phys. Chem. B 111: 10453-10460.
10. Gurtovenko AA, Anwar J, (2007) Ion transport through chemically induced pores in protein-free phospholipid membranes. J. Phys. Chem. B 111: 13379-13382.
11. Notman R, Noro MG, O'Malley B, Anwar J, (2006) Molecular basis for dimethylsulfoxide (DMSO) action on lipid membranes. J. Am. Chem. Soc. 128: 13982-13983.
12. Callaghan R, van Gorkom LCM, Epand RM, (1992) A comparison of membrane properties and composition between cell lines selected and transfected for multi drug resistance. Br. J. Cancer. 66: 781-786.
13. Melkonyan H, Sorg C, Klempt M, (1996) Electroporation efficiency in mammalian cells is increased by dimethyl sulfoxide (DMSO). Nucl. Acids Res. 24: 4356-4357.
14. Davis JH, (1983) The description of membrane lipid conformation, order and dynamics by 2H-NMR. Biochim. Biophys. Acta. 737: 117-171.
15. Aittoniemi J, Róg T, Niemelä P, Pasenkiewicz-Gierula M, Karttunen M, et al. (2006) Tilt: major factor in sterols' ordering capability in membranes. J. Phys. Chem. B. 110: 25562-25564.
16. Vernier PT, Ziegler MJ, (2007) Nanosecond field alignment of head group and water dipoles in electroporating phospholipid bilayers. J. Phys. Chem. B. 111: 12993-12996.
17. Ziegler MJ, Vernier PT, (2008) Interface water dynamics and porating electric fields for phospholipid bilayers. J. Phys. Chem. B. 112: 13588-13596.
18. Tarek M, (2005) Membrane electroporation: a molecular dynamics simulation. Biophys. J. 88: 4045-4053.
19. Levine ZA, Vernier PT, (2010) Life cycle of an electropore: field-dependent and field-independent steps in pore creation and annihilation. J. Membrane Biol. 236: 27-36.
20. Fernández ML, Marshall G, Sagués F, Reigada R, (2010) Structural and kinetic molecular dynamics study of electroporation in cholesterol-containing bilayers. J. Phys. Chem. B. 114: 6855-6865.
21. Reigada R, Fernández ML, (2011) Structure and electroporation of lipid bilayers: a molecular study. XXXth URSI GASS congress book (http://ursigass2011.org/abstracts/AbstractBook_v2.htm).
22. Vernier PT, Levine ZA, Wu YH, Joubert V, Ziegler MJ, et al. (2009) Electroporating fields target oxidatively damaged areas in the cell membrane. PLoS One. 4: e7966.
23. Vernier PT, Sun Y, Gundersen MA, (2006) Nanoelectropulse-driven membrane perturbation and small molecule permeabilization. BMC Cell. Biol. 19: 7-37.
24. Bowman AM, Nesin OM, Pakhomova ON, Pakhomov AG, (2010) Analysis of plasma membrane integrity by fluorescent detection of Tl(+) uptake. J. Membr. Biol. 236: 14-26.
25. Fackler OT, Grosse R, (2008) Cell motility through plasma membrane blebbing. J. Cell. Biol. 181: 879-84.
26. Tsong TY, (1991) Electroporation of cell membranes. Biophys. J. 60: 297-306.
27. Runckle DN, Swanson JR, (1980) Effect of dimethyl sulfoxide on serum osmolality. Clin. Chem. 26: 1745-1747.
28. Okada Y, (2004) Ion channels and transporters involved in cell volume regulation and sensor mechanisms. Cell Biochem. Biophys. 41: 233-258.
29. Kinosita K Jr, Tsong TY, (1977) Formation and resealing of pores of controlled sizes in human erythrocyte membrane. Nature. 268: 438-441.
30. Day JG, Stacey GN, (2007) Cryopreservation and Freez-Drying Protocols, second edition. Ed.; Humana Press, Totowa, New Jersey. 77 p.
31. Valdez CA, Mazni OA, Takahashi Y, Fujikawa S, Kanagawa H, (1992) Successful cryopreservation of mouse blastocysts using a new vitrification solution.J. Reprod. Fert. 96: 793-802.
32. Lindahl E, Hess B, van der Spoel D, (2001) GROMACS 3.0: a package for molecular simulation and trajectory analysis. J. Mol. Model. 7: 306-317.
33. Berger O, Edholm O, Jahnig F, (1997) Molecular dynamics simulations of a fluid bilayer of dipalmitoylphosphatidylcholine at full hydration, constant pressure, and constant temperature. Biophys. J. 72: 2002-2013.
34. Tieleman DP, Berendsen HJC, (1996) Molecular dynamics simulations of a fully hydrated dipalmitoylphosphatidylcholine bilayer with different macroscopic boundary conditions and parameters. J. Chem. Phys. 105: 4871-4880.
35. Bachar M, Brunelle P, Tieleman DP, Rauk A, (2004) Molecular dynamics simulation of a polyunsaturated lipid bilayer susceptible to lipid peroxidation. J. Phys. Chem. B. 108: 7170-7179.
36. Martinez-Seara H, Róg T, Karttunen M, Reigada R, Vattulainen I, (2008) Influence of cis double-bond parameterization on lipid membrane properties: how seemingly insignificant details in force-field change even qualitative trends. J. Chem. Phys. 129: 105103.
37. Holtje M, Forster T, Brandt B, Engels T, von Rybinski W, et al. (2001) Molecular dynamics simulations of stratum corneum lipid models: fatty acids and cholesterol. Biochim. Biophys. Acta. 1511: 156-167.
38. Bordat P, Sacristan J, Reith D, Girard S, Glättli A, et al. (2003) An improved dimethyl sulfoxide force field for molecular dynamics simulations. Chem. Phys. Lett. 374: 201-205.
39. Berendsen HJC, Postma JPM, van Gunsteren WF, DiNola A, Haak JR, (1984) Molecular dynamics with coupling to an external bath. J. Chem. Phys. 81: 3684-3690.
40. Martinez-Seara H, Róg T, Pasenkiewicz-Gierula M, Vattulainen I, Karttunen M, et al. (2008) Interplay of unsaturated phospholipids and cholesterol in membranes: effect of double-bond position. Biophys. J. 95: 3295-3305.
41. Hung WC, Lee MT, Chen FY, Huang HW, (2007) The condensing effect of cholesterol in lipid bilayers. Biophys. J. 92: 3960-3967.
42. Biedler JL, Riehm H, (1970) Cellular resistance to actinomycinD in Chinese Hamster cells in vitro: Cross-resistance, radioautographic, and cytogenetic studies. Cancer Res 30, 1174-1184.