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Volumn 10, Issue 4, 2014, Pages

Exact Hybrid Particle/Population Simulation of Rule-Based Models of Biochemical Systems

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; COST BENEFIT ANALYSIS; MONTE CARLO METHODS; ORDINARY DIFFERENTIAL EQUATIONS; PROTEINS; STOCHASTIC SYSTEMS;

EID: 84901341450     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1003544     Document Type: Article
Times cited : (32)

References (81)
  • 5
    • 10244219918 scopus 로고    scopus 로고
    • BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains
    • Blinov ML, Faeder JR, Goldstein B, Hlavacek WS, (2004) BioNetGen: software for rule-based modeling of signal transduction based on the interactions of molecular domains. Bioinformatics 17: 3289-3291.
    • (2004) Bioinformatics , vol.17 , pp. 3289-3291
    • Blinov, M.L.1    Faeder, J.R.2    Goldstein, B.3    Hlavacek, W.S.4
  • 6
    • 65649154507 scopus 로고    scopus 로고
    • Rule-based modeling of biochemical systems with BioNetGen
    • Clifton, N.J.: Humana Press
    • Faeder JR, Blinov ML, Hlavacek WS (2009) Rule-based modeling of biochemical systems with BioNetGen. In: Methods in Molecular Biology, Clifton, N.J.: Humana Press, volume 500. pp. 113-167.
    • (2009) Methods in Molecular Biology , vol.500 , pp. 113-167
    • Faeder, J.R.1    Blinov, M.L.2    Hlavacek, W.S.3
  • 7
    • 4444382239 scopus 로고    scopus 로고
    • Formal molecular biology
    • Danos V, Laneve C, (2004) Formal molecular biology. Theor Comput Sci 325: 69-110.
    • (2004) Theor Comput Sci , vol.325 , pp. 69-110
    • Danos, V.1    Laneve, C.2
  • 9
    • 80054062207 scopus 로고    scopus 로고
    • Rule-based multi-level modeling of cell biological systems
    • Maus C, Rybacki S, Uhrmacher AM, (2011) Rule-based multi-level modeling of cell biological systems. BMC Syst Biol 5: 166.
    • (2011) BMC Syst Biol , vol.5 , pp. 166
    • Maus, C.1    Rybacki, S.2    Uhrmacher, A.M.3
  • 11
    • 69949127857 scopus 로고    scopus 로고
    • Efficient stochastic simulation of reaction-diffusion processes via direct compilation
    • Lis M, Artyomov MN, Devadas S, Chakraborty AK, (2009) Efficient stochastic simulation of reaction-diffusion processes via direct compilation. Bioinformatics 25: 2289-2291.
    • (2009) Bioinformatics , vol.25 , pp. 2289-2291
    • Lis, M.1    Artyomov, M.N.2    Devadas, S.3    Chakraborty, A.K.4
  • 12
    • 84862777639 scopus 로고    scopus 로고
    • Computational modeling of cellular signaling processes embedded into dynamic spatial contexts
    • Angermann BR, Klauschen F, Garcia AD, Prustel T, Zhang F, et al. (2012) Computational modeling of cellular signaling processes embedded into dynamic spatial contexts. Nat Meth 9: 283-289.
    • (2012) Nat Meth , vol.9 , pp. 283-289
    • Angermann, B.R.1    Klauschen, F.2    Garcia, A.D.3    Prustel, T.4    Zhang, F.5
  • 13
    • 80054099633 scopus 로고    scopus 로고
    • Toward a comprehensive language for biological systems
    • Faeder J, (2011) Toward a comprehensive language for biological systems. BMC Biol 9: 68.
    • (2011) BMC Biol , vol.9 , pp. 68
    • Faeder, J.1
  • 14
    • 84887358097 scopus 로고    scopus 로고
    • Rule-based modeling of signal transduction: A primer
    • Clifton, N.J.: Humana Press
    • Sekar JAP, Faeder JR (2012) Rule-based modeling of signal transduction: A primer. In: Methods In Molecular Biology, Clifton, N.J.: Humana Press, volume 880. pp. 139-218.
    • (2012) Methods In Molecular Biology , vol.880 , pp. 139-218
    • Sekar, J.A.P.1    Faeder, J.R.2
  • 16
    • 79551555393 scopus 로고    scopus 로고
    • Efficient modeling, simulation and coarse-graining of biological complexity with NFsim
    • Sneddon MW, Faeder JR, Emonet T, (2011) Efficient modeling, simulation and coarse-graining of biological complexity with NFsim. Nat Meth 8: 177-183.
    • (2011) Nat Meth , vol.8 , pp. 177-183
    • Sneddon, M.W.1    Faeder, J.R.2    Emonet, T.3
  • 18
    • 32044469862 scopus 로고    scopus 로고
    • A network model of early events in epidermal growth factor receptor signaling that accounts for combinatorial complexity
    • Blinov ML, Faeder JR, Goldstein B, Hlavacek WS, (2006) A network model of early events in epidermal growth factor receptor signaling that accounts for combinatorial complexity. Biosystems 83: 136-151.
    • (2006) Biosystems , vol.83 , pp. 136-151
    • Blinov, M.L.1    Faeder, J.R.2    Goldstein, B.3    Hlavacek, W.S.4
  • 20
    • 0017030517 scopus 로고
    • A general method for numerically simulating the stochastic time evolution of coupled chemical reactions
    • Gillespie DT, (1976) A general method for numerically simulating the stochastic time evolution of coupled chemical reactions. J Comput Phys 22: 403-434.
    • (1976) J Comput Phys , vol.22 , pp. 403-434
    • Gillespie, D.T.1
  • 21
    • 0542389101 scopus 로고
    • The Markoff-automaton: a new algorithm for simulating the timeevolution of large stochastic dynamic systems
    • Fricke T, Wendt D, (1995) The Markoff-automaton: a new algorithm for simulating the timeevolution of large stochastic dynamic systems. Int J Mod Phys C 6: 277-306.
    • (1995) Int J Mod Phys C , vol.6 , pp. 277-306
    • Fricke, T.1    Wendt, D.2
  • 22
    • 33749989765 scopus 로고    scopus 로고
    • A "partitioned leaping" approach for multiscale modeling of chemical reaction dynamics
    • Harris LA, Clancy P, (2006) A "partitioned leaping" approach for multiscale modeling of chemical reaction dynamics. J Chem Phys 125: 144107.
    • (2006) J Chem Phys , vol.125 , pp. 144107
    • Harris, L.A.1    Clancy, P.2
  • 23
    • 51849129931 scopus 로고    scopus 로고
    • Kinetic Monte Carlo method for rule-based modeling of biochemical networks
    • Yang J, Monine MI, Faeder JR, Hlavacek WS, (2008) Kinetic Monte Carlo method for rule-based modeling of biochemical networks. Phys Rev E 78: 031910.
    • (2008) Phys Rev E , vol.78 , pp. 031910
    • Yang, J.1    Monine, M.I.2    Faeder, J.R.3    Hlavacek, W.S.4
  • 25
    • 0002296942 scopus 로고
    • A new algorithm for Monte Carlo simulation of Ising spin systems
    • Bortz AB, Kalos MH, Lebowitz JL, (1975) A new algorithm for Monte Carlo simulation of Ising spin systems. J Comput Phys 17: 10-18.
    • (1975) J Comput Phys , vol.17 , pp. 10-18
    • Bortz, A.B.1    Kalos, M.H.2    Lebowitz, J.L.3
  • 28
    • 85036477905 scopus 로고    scopus 로고
    • Using the SRSim software for spatial and rule-based modeling of combinatorially complex biochemical reaction systems
    • Grünert G, Dittrich P, (2011) Using the SRSim software for spatial and rule-based modeling of combinatorially complex biochemical reaction systems. Lect Notes Comput Sci 6501: 240-256.
    • (2011) Lect Notes Comput Sci , vol.6501 , pp. 240-256
    • Grünert, G.1    Dittrich, P.2
  • 29
    • 80052688663 scopus 로고    scopus 로고
    • The efficiency of reactant site sampling in network-free simulation of rule-based models for biochemical systems
    • Yang J, Hlavacek WS, (2011) The efficiency of reactant site sampling in network-free simulation of rule-based models for biochemical systems. Phys Biol 8: 055009.
    • (2011) Phys Biol , vol.8 , pp. 055009
    • Yang, J.1    Hlavacek, W.S.2
  • 30
    • 0035371624 scopus 로고    scopus 로고
    • Whole-cell simulation: a grand challenge of the 21st century
    • Tomita M, (2001) Whole-cell simulation: a grand challenge of the 21st century. Trends Biotechnol 19: 205-210.
    • (2001) Trends Biotechnol , vol.19 , pp. 205-210
    • Tomita, M.1
  • 31
    • 84864258618 scopus 로고    scopus 로고
    • A whole-cell computational model predicts phenotype from genotype
    • Karr JR, Sanghvi JC, Macklin DN, Gutschow MV, Jacobs JM, et al. (2012) A whole-cell computational model predicts phenotype from genotype. Cell 150: 389-401.
    • (2012) Cell , vol.150 , pp. 389-401
    • Karr, J.R.1    Sanghvi, J.C.2    Macklin, D.N.3    Gutschow, M.V.4    Jacobs, J.M.5
  • 33
    • 77953891646 scopus 로고    scopus 로고
    • Snapshot: Key numbers in biology
    • Moran U, Phillips R, Milo R, (2010) Snapshot: Key numbers in biology. Cell 141: 1262-1262.e1.
    • (2010) Cell , vol.141 , pp. 1262
    • Moran, U.1    Phillips, R.2    Milo, R.3
  • 35
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical reactions
    • Gillespie DT, (1977) Exact stochastic simulation of coupled chemical reactions. J Phys Chem 81: 2340-2361.
    • (1977) J Phys Chem , vol.81 , pp. 2340-2361
    • Gillespie, D.T.1
  • 36
    • 34249950625 scopus 로고    scopus 로고
    • Stochastic simulation of chemical kinetics
    • Gillespie DT, (2007) Stochastic simulation of chemical kinetics. Annu Rev Phys Chem 58: 35-55.
    • (2007) Annu Rev Phys Chem , vol.58 , pp. 35-55
    • Gillespie, D.T.1
  • 37
    • 0001144902 scopus 로고    scopus 로고
    • Efficient exact stochastic simulation of chemical systems with many species and many channels
    • Gibson MA, Bruck J, (2000) Efficient exact stochastic simulation of chemical systems with many species and many channels. J Phys Chem A 104: 1876-1889.
    • (2000) J Phys Chem A , vol.104 , pp. 1876-1889
    • Gibson, M.A.1    Bruck, J.2
  • 38
    • 4644266081 scopus 로고    scopus 로고
    • Efficient formulation of the stochastic simulation algorithm for chemically reacting systems
    • Cao Y, Li H, Petzold L, (2004) Efficient formulation of the stochastic simulation algorithm for chemically reacting systems. J Chem Phys 121: 4059-4067.
    • (2004) J Chem Phys , vol.121 , pp. 4059-4067
    • Cao, Y.1    Li, H.2    Petzold, L.3
  • 39
    • 44649178886 scopus 로고    scopus 로고
    • A constant-time kinetic Monte Carlo algorithm for simulation of large biochemical reaction networks
    • Slepoy A, Thompson AP, Plimpton SJ, (2008) A constant-time kinetic Monte Carlo algorithm for simulation of large biochemical reaction networks. J Chem Phys 128: 205101.
    • (2008) J Chem Phys , vol.128 , pp. 205101
    • Slepoy, A.1    Thompson, A.P.2    Plimpton, S.J.3
  • 40
    • 38049004035 scopus 로고    scopus 로고
    • Efficient kinetic Monte Carlo simulation
    • Schulze TP, (2008) Efficient kinetic Monte Carlo simulation. J Comput Phys 227: 2455-2462.
    • (2008) J Comput Phys , vol.227 , pp. 2455-2462
    • Schulze, T.P.1
  • 41
    • 31344458755 scopus 로고    scopus 로고
    • The sorting direct method for stochastic simulation of biochemical systems with varying reaction execution behavior
    • McCollum JM, Peterson GD, Cox CD, Simpson ML, Samatova NF, (2006) The sorting direct method for stochastic simulation of biochemical systems with varying reaction execution behavior. Comput Biol Chem 30: 39-49.
    • (2006) Comput Biol Chem , vol.30 , pp. 39-49
    • McCollum, J.M.1    Peterson, G.D.2    Cox, C.D.3    Simpson, M.L.4    Samatova, N.F.5
  • 42
    • 74049105596 scopus 로고    scopus 로고
    • Modeling multivalent ligandreceptor interactions with steric constraints on configurations of cell-surface receptor aggregates
    • Monine MI, Posner RG, Savage PB, Faeder JR, Hlavacek WS, (2010) Modeling multivalent ligandreceptor interactions with steric constraints on configurations of cell-surface receptor aggregates. Biophys J 98: 48-56.
    • (2010) Biophys J , vol.98 , pp. 48-56
    • Monine, M.I.1    Posner, R.G.2    Savage, P.B.3    Faeder, J.R.4    Hlavacek, W.S.5
  • 43
    • 44049093878 scopus 로고    scopus 로고
    • Stochastic severing of actin filaments by actin depolymerizing factor/cofilin controls the emergence of a steady dynamical regime
    • Roland J, Berro J, Michelot A, Blanchoin L, Martiel JL, (2008) Stochastic severing of actin filaments by actin depolymerizing factor/cofilin controls the emergence of a steady dynamical regime. Biophys J 94: 2082-2094.
    • (2008) Biophys J , vol.94 , pp. 2082-2094
    • Roland, J.1    Berro, J.2    Michelot, A.3    Blanchoin, L.4    Martiel, J.L.5
  • 44
    • 0037109565 scopus 로고    scopus 로고
    • Approximate simulation of coupled fast and slow reactions for stochastic chemical kinetics
    • Haseltine EL, Rawlings JB, (2002) Approximate simulation of coupled fast and slow reactions for stochastic chemical kinetics. J Chem Phys 117: 6959-6969.
    • (2002) J Chem Phys , vol.117 , pp. 6959-6969
    • Haseltine, E.L.1    Rawlings, J.B.2
  • 46
    • 1542400036 scopus 로고    scopus 로고
    • A multi-algorithm, multi-timescale method for cell simulation
    • Takahashi K, Kaizu K, Hu B, Tomita M, (2004) A multi-algorithm, multi-timescale method for cell simulation. Bioinformatics 20: 538-546.
    • (2004) Bioinformatics , vol.20 , pp. 538-546
    • Takahashi, K.1    Kaizu, K.2    Hu, B.3    Tomita, M.4
  • 47
    • 0347724159 scopus 로고    scopus 로고
    • Adaptive stochastic-deterministic chemical kinetic simulations
    • Vasudeva K, Bhalla US, (2004) Adaptive stochastic-deterministic chemical kinetic simulations. Bioinformatics 20: 78-84.
    • (2004) Bioinformatics , vol.20 , pp. 78-84
    • Vasudeva, K.1    Bhalla, U.S.2
  • 48
    • 2442438819 scopus 로고    scopus 로고
    • A multi-scaled approach for simulating chemical reaction systems
    • Burrage K, Tian T, Burrage P, (2004) A multi-scaled approach for simulating chemical reaction systems. Prog Biophys Mol Bio 85: 217-234.
    • (2004) Prog Biophys Mol Bio , vol.85 , pp. 217-234
    • Burrage, K.1    Tian, T.2    Burrage, P.3
  • 49
    • 22944451159 scopus 로고    scopus 로고
    • Accurate hybrid stochastic simulation of a system of coupled chemical or biochemical reactions
    • Salis H, Kaznessis Y, (2005) Accurate hybrid stochastic simulation of a system of coupled chemical or biochemical reactions. J Chem Phys 122: 054103.
    • (2005) J Chem Phys , vol.122 , pp. 054103
    • Salis, H.1    Kaznessis, Y.2
  • 50
    • 33645465102 scopus 로고    scopus 로고
    • Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
    • Salis H, Sotiropoulos V, Kaznessis YN, (2006) Multiscale Hy3S: Hybrid stochastic simulation for supercomputers. BMC Bioinformatics 7: 93.
    • (2006) BMC Bioinformatics , vol.7 , pp. 93
    • Salis, H.1    Sotiropoulos, V.2    Kaznessis, Y.N.3
  • 51
    • 33750970021 scopus 로고    scopus 로고
    • Dynamic partitioning for hybrid simulation of the bistable HIV-1 transactivation network
    • Griffith M, Courtney T, Peccoud J, Sanders WH, (2006) Dynamic partitioning for hybrid simulation of the bistable HIV-1 transactivation network. Bioinformatics 22: 2782-2789.
    • (2006) Bioinformatics , vol.22 , pp. 2782-2789
    • Griffith, M.1    Courtney, T.2    Peccoud, J.3    Sanders, W.H.4
  • 52
    • 33746516694 scopus 로고    scopus 로고
    • A hybrid deterministic-stochastic algorithm for modeling cell signaling dynamics in spatially inhomogeneous environments and under the influence of external fields
    • Wylie DC, Hori Y, Dinner AR, Chakraborty AK, (2006) A hybrid deterministic-stochastic algorithm for modeling cell signaling dynamics in spatially inhomogeneous environments and under the influence of external fields. J Phys Chem B 110: 12749-12765.
    • (2006) J Phys Chem B , vol.110 , pp. 12749-12765
    • Wylie, D.C.1    Hori, Y.2    Dinner, A.R.3    Chakraborty, A.K.4
  • 53
    • 84856421347 scopus 로고    scopus 로고
    • Hybrid modeling and simulation of stochastic effects on progression through the eukaryotic cell cycle
    • Liu Z, Pu Y, Li F, Shaffer CA, Hoops S, et al. (2012) Hybrid modeling and simulation of stochastic effects on progression through the eukaryotic cell cycle. J Chem Phys 136: 034105.
    • (2012) J Chem Phys , vol.136 , pp. 034105
    • Liu, Z.1    Pu, Y.2    Li, F.3    Shaffer, C.A.4    Hoops, S.5
  • 54
    • 79951641252 scopus 로고    scopus 로고
    • Multistate modeling and simulation for regulatory networks
    • In: Johansson B, Jain S, Montoya-Torres J, Hugan J, Yücesan E, editors
    • Liu Z, Mobassera UJ, Shaffer CA, Watson LT, Cao Y (2010) Multistate modeling and simulation for regulatory networks. In: Johansson B, Jain S, Montoya-Torres J, Hugan J, Yücesan E, editors, Proceedings of the 2010 Winter Simulation Conference. pp. 631-642.
    • (2010) Proceedings of the 2010 Winter Simulation Conference , pp. 631-642
    • Liu, Z.1    Mobassera, U.J.2    Shaffer, C.A.3    Watson, L.T.4    Cao, Y.5
  • 55
    • 84889583170 scopus 로고    scopus 로고
    • Pleomorphic ensembles: Formation of large clusters composed of weakly interacting multivalent molecules
    • Falkenberg CV, Blinov ML, Loew LM, (2013) Pleomorphic ensembles: Formation of large clusters composed of weakly interacting multivalent molecules. Biophys J 105: 2451-2460.
    • (2013) Biophys J , vol.105 , pp. 2451-2460
    • Falkenberg, C.V.1    Blinov, M.L.2    Loew, L.M.3
  • 56
    • 14844289958 scopus 로고    scopus 로고
    • Automatic generation of cellular reaction networks with Moleculizer 1.0
    • Lok L, Brent R, (2005) Automatic generation of cellular reaction networks with Moleculizer 1.0. Nat Biotechnol 23: 131-136.
    • (2005) Nat Biotechnol , vol.23 , pp. 131-136
    • Lok, L.1    Brent, R.2
  • 58
    • 84865165310 scopus 로고    scopus 로고
    • Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling
    • Creamer M, Stites E, Aziz M, Cahill J, Tan C, et al. (2012) Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling. BMC Syst Biol 6: 107.
    • (2012) BMC Syst Biol , vol.6 , pp. 107
    • Creamer, M.1    Stites, E.2    Aziz, M.3    Cahill, J.4    Tan, C.5
  • 59
    • 23244465153 scopus 로고    scopus 로고
    • Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity
    • Borisov NM, Markevich NI, Hoek JB, Kholodenko BN, (2005) Signaling through receptors and scaffolds: independent interactions reduce combinatorial complexity. Biophys J 89: 951-966.
    • (2005) Biophys J , vol.89 , pp. 951-966
    • Borisov, N.M.1    Markevich, N.I.2    Hoek, J.B.3    Kholodenko, B.N.4
  • 60
    • 32044464102 scopus 로고    scopus 로고
    • Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains
    • Borisov NM, Markevich NI, Hoek JB, Kholodenko BN, (2006) Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains. Biosystems 83: 152-166.
    • (2006) Biosystems , vol.83 , pp. 152-166
    • Borisov, N.M.1    Markevich, N.I.2    Hoek, J.B.3    Kholodenko, B.N.4
  • 61
    • 54549107992 scopus 로고    scopus 로고
    • Exact model reduction of combinatorial reaction networks
    • Conzelmann H, Fey D, Gilles ED, (2008) Exact model reduction of combinatorial reaction networks. BMC Syst Biol 2: 78.
    • (2008) BMC Syst Biol , vol.2 , pp. 78
    • Conzelmann, H.1    Fey, D.2    Gilles, E.D.3
  • 65
    • 0021238610 scopus 로고
    • Equilibrium theory for the clustering of bivalent cell surface receptors by trivalent ligands. Application to histamine release from basophils
    • Goldstein B, Perelson AS, (1984) Equilibrium theory for the clustering of bivalent cell surface receptors by trivalent ligands. Application to histamine release from basophils. Biophys J 45: 1109-1123.
    • (1984) Biophys J , vol.45 , pp. 1109-1123
    • Goldstein, B.1    Perelson, A.S.2
  • 66
    • 0037459075 scopus 로고    scopus 로고
    • Cellular motility driven by assembly and disassembly of actin filaments
    • Pollard TD, Borisy GG, (2003) Cellular motility driven by assembly and disassembly of actin filaments. Cell 112: 453-465.
    • (2003) Cell , vol.112 , pp. 453-465
    • Pollard, T.D.1    Borisy, G.G.2
  • 67
    • 34548475260 scopus 로고    scopus 로고
    • Emergence of largescale cell morphology and movement from local actin filament growth dynamics
    • Lacayo CI, Pincus Z, VanDuijn MM, Wilson CA, Fletcher DA, et al. (2007) Emergence of largescale cell morphology and movement from local actin filament growth dynamics. PLOS Biol 5: e233.
    • (2007) PLOS Biol , vol.5
    • Lacayo, C.I.1    Pincus, Z.2    VanDuijn, M.M.3    Wilson, C.A.4    Fletcher, D.A.5
  • 70
    • 0037378771 scopus 로고    scopus 로고
    • Investigation of early events in FcεRI-mediated signaling using a detailed mathematical model
    • Faeder JR, Hlavacek WS, Reischl I, Blinov ML, Metzger H, et al. (2003) Investigation of early events in FcεRI-mediated signaling using a detailed mathematical model. J Immunol 170: 3769-3781.
    • (2003) J Immunol , vol.170 , pp. 3769-3781
    • Faeder, J.R.1    Hlavacek, W.S.2    Reischl, I.3    Blinov, M.L.4    Metzger, H.5
  • 71
    • 35348988164 scopus 로고    scopus 로고
    • Network analysis of oncogenic Ras activation in cancer
    • Stites EC, Trampont PC, Ma Z, Ravichandran KS, (2007) Network analysis of oncogenic Ras activation in cancer. Science 318: 463-467.
    • (2007) Science , vol.318 , pp. 463-467
    • Stites, E.C.1    Trampont, P.C.2    Ma, Z.3    Ravichandran, K.S.4
  • 72
    • 33646852421 scopus 로고    scopus 로고
    • Dynamics of the Ras/ERK MAPK cascade as monitored by uorescent probes
    • Fujioka A, Terai K, Itoh RE, Aoki K, Nakamura T, et al. (2006) Dynamics of the Ras/ERK MAPK cascade as monitored by uorescent probes. J Biol Chem 281: 8917-8926.
    • (2006) J Biol Chem , vol.281 , pp. 8917-8926
    • Fujioka, A.1    Terai, K.2    Itoh, R.E.3    Aoki, K.4    Nakamura, T.5
  • 73
    • 0028863504 scopus 로고
    • Guanine nucleotide exchange factors: activators of Ras superfamily proteins
    • Overbeck AF, Brtva TR, Cox AD, Graham SM, Huff SY, et al. (1995) Guanine nucleotide exchange factors: activators of Ras superfamily proteins. Mol Reprod Dev 42: 468-476.
    • (1995) Mol Reprod Dev , vol.42 , pp. 468-476
    • Overbeck, A.F.1    Brtva, T.R.2    Cox, A.D.3    Graham, S.M.4    Huff, S.Y.5
  • 74
    • 0001884644 scopus 로고
    • Individual comparisons by ranking methods
    • Wilcoxon F, (1945) Individual comparisons by ranking methods. Biometrics Bull 1: 80-83.
    • (1945) Biometrics Bull , vol.1 , pp. 80-83
    • Wilcoxon, F.1
  • 75
    • 0002322469 scopus 로고
    • On a test of whether one of two random variables is stochastically larger than the other
    • Mann HB, (1947) On a test of whether one of two random variables is stochastically larger than the other. Ann Math Stat 18: 50-60.
    • (1947) Ann Math Stat , vol.18 , pp. 50-60
    • Mann, H.B.1
  • 76
    • 0001454867 scopus 로고
    • On the criterion that a given system of deviations from the probable in the case of a correlated system of variables is such that it can be reasonably supposed to have arisen from random sampling
    • Pearson K, (1900) On the criterion that a given system of deviations from the probable in the case of a correlated system of variables is such that it can be reasonably supposed to have arisen from random sampling. Philos Mag 50: 157-175.
    • (1900) Philos Mag , vol.50 , pp. 157-175
    • Pearson, K.1
  • 77
    • 0035933994 scopus 로고    scopus 로고
    • Approximate accelerated stochastic simulation of chemically reacting systems
    • Gillespie DT, (2001) Approximate accelerated stochastic simulation of chemically reacting systems. J Chem Phys 115: 1716-1733.
    • (2001) J Chem Phys , vol.115 , pp. 1716-1733
    • Gillespie, D.T.1
  • 78
    • 0242425970 scopus 로고    scopus 로고
    • Improved leap-size selection for accelerated stochastic simulation
    • Gillespie DT, Petzold LR, (2003) Improved leap-size selection for accelerated stochastic simulation. J Chem Phys 119: 8229-8234.
    • (2003) J Chem Phys , vol.119 , pp. 8229-8234
    • Gillespie, D.T.1    Petzold, L.R.2
  • 79
    • 31544465969 scopus 로고    scopus 로고
    • Efficient step size selection for the tau-leaping simulation method
    • Cao Y, Gillespie DT, Petzold LR, (2006) Efficient step size selection for the tau-leaping simulation method. J Chem Phys 124: 044109.
    • (2006) J Chem Phys , vol.124 , pp. 044109
    • Cao, Y.1    Gillespie, D.T.2    Petzold, L.R.3
  • 80
    • 56249090033 scopus 로고    scopus 로고
    • Temporal coarse-graining of microscopic-lattice kinetic Monte Carlo simulations via T leaping
    • Vlachos DG, (2008) Temporal coarse-graining of microscopic-lattice kinetic Monte Carlo simulations via T leaping. Phys Rev E 78: 046713.
    • (2008) Phys Rev E , vol.78 , pp. 046713
    • Vlachos, D.G.1
  • 81
    • 2942588906 scopus 로고    scopus 로고
    • Mathematical and computational models of immunereceptor signalling
    • Goldstein B, Faeder JR, Hlavacek WS, (2004) Mathematical and computational models of immunereceptor signalling. Nat Rev Immunol 4: 445-456.
    • (2004) Nat Rev Immunol , vol.4 , pp. 445-456
    • Goldstein, B.1    Faeder, J.R.2    Hlavacek, W.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.