Investigation of the retention behavior of structurally diverse drugs on alpha1 acid glycoprotein column: Insight on the molecular factors involved and correlation with protein binding data

European Journal of Pharmaceutical Sciences

Volumn 60, Issue , 2014, Pages 24-31

  Chrysanthakopoulos, Marios ^a   Vallianatou, Theodosia ^a   Giaginis, Costas ^b   Tsantili Kakoulidou, Anna ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF THE AEGEAN   (Greece)

Author keywords

Biomimetic chromatography; Human serum albumin; Linear solvation energy relationships; Lipophilicity; Retention affinity relationships

Indexed keywords

AMITRIPTYLINE; ATENOLOL; CAPTOPRIL; CARBAMAZEPINE; CEFORANIDE; CEFOXITIN; CEFTAZIDIME; CHLORPHENIRAMINE; CHLORPROMAZINE; CLOMIPRAMINE; DIAZEPAM; DILTIAZEM; DIPHENHYDRAMINE; DIPYRIDAMOLE; DOXEPIN; FLUNITRAZEPAM; FLUOXETINE; IMIPRAMINE; INDOMETACIN; KETOPROFEN; LIDOCAINE; LORAZEPAM; NAPROXEN; NIFEDIPINE; NORTRIPTYLINE; OROSOMUCOID; PARACETAMOL; PENTOBARBITAL; PHENAZONE; UNINDEXED DRUG; 2 PROPANOL; ACETONITRILE; ACETONITRILE DERIVATIVE; DRUG; PROTEIN BINDING;

ACIDITY; ARTICLE; DRUG RETENTION; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; IONIZATION; LIGAND BINDING; LIPOPHILICITY; MOLECULAR WEIGHT; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN BINDING; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLVATION; STATIC ELECTRICITY; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM;

2-PROPANOL; ACETONITRILES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROGEN BONDING; OROSOMUCOID; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; STATIC ELECTRICITY;

EID: 84901289570     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2014.04.015     Document Type: Article

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