Enantioselective retention of β-blocking agents on human serum albumin and α1-acid glycoprotein HPLC columns: Relationships with different scales of lipophilicity

European Journal of Pharmaceutical Sciences

Volumn 38, Issue 5, 2009, Pages 472-478

  Barbato, Francesco ^a   Carpentiero, Carmen ^a   Grumetto, Lucia ^a   La Rotonda, Maria Immacolata ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

1 Acid glycoprotein; Beta blockers; Biochromatography; Enantioselectivity; Human serum albumin; Lipophilicity

Indexed keywords

ACEBUTOLOL; ALPRENOLOL; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETAXOLOL; HUMAN SERUM ALBUMIN; LABETALOL; METOPROLOL; NADOLOL; NEBIVOLOL; OCTANOL; OROSOMUCOID; OXPRENOLOL; PINDOLOL; PROPRANOLOL; SOTALOL; TIMOLOL;

ARTICLE; ARTIFICIAL MEMBRANE; BINDING COMPETITION; CONTROLLED STUDY; DRUG BINDING SITE; ENANTIOMER; ENANTIOSELECTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; MOLECULAR RECOGNITION; PLASMA PROTEIN BINDING; PRIORITY JOURNAL;

ADRENERGIC BETA-ANTAGONISTS; BINDING, COMPETITIVE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG INTERACTIONS; HUMANS; HYDROGEN-ION CONCENTRATION; OROSOMUCOID; PHOSPHOLIPIDS; PROTEIN BINDING; SERUM ALBUMIN; SOLUBILITY; STEREOISOMERISM;

EID: 70449522045     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2009.09.011     Document Type: Article

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