Absolute flow or myocardial flow reserve for the detection of significant coronary artery disease?

European Heart Journal Cardiovascular Imaging

Volumn 15, Issue 6, 2014, Pages 659-665

  Joutsiniemi, Esa ^a   Saraste, Antti ^a,b   Pietilä, Mikko ^a   Mäki, Maija ^a,b   Kajander, Sami ^b   Ukkonen, Heikki ^a,b   Airaksinen, Juhani ^a   Knuuti, Juhani ^b  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b TURKU PET CENTRE   (Finland)

Author keywords

Coronary artery disease; Myocardial blood flow; Myocardial perfusion imaging; Myocardial perfusion reserve; Positron emission tomography

Indexed keywords

ADENOSINE; WATER O 15; BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY CIRCUMFLEX BRANCH; CORONARY ARTERY DISEASE; DIAGNOSTIC VALUE; FEMALE; FRACTIONAL FLOW RESERVE; HUMAN; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MAJOR CLINICAL STUDY; MALE; POSITRON EMISSION TOMOGRAPHY; PREDICTIVE VALUE; PRIORITY JOURNAL; RIGHT CORONARY ARTERY; STRESS ECHOCARDIOGRAPHY; COHORT ANALYSIS; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; MIDDLE AGED; MULTIMODAL IMAGING; MYOCARDIAL PERFUSION IMAGING; PHYSIOLOGY; PROCEDURES; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; VERY ELDERLY;

ADRENERGIC BETA-ANTAGONISTS; AGED; AGED, 80 AND OVER; COHORT STUDIES; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; FRACTIONAL FLOW RESERVE, MYOCARDIAL; HUMANS; MALE; MIDDLE AGED; MULTIMODAL IMAGING; MYOCARDIAL PERFUSION IMAGING; POSITRON-EMISSION TOMOGRAPHY; PROSPECTIVE STUDIES; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84901279303     PISSN: 20472404     EISSN: 20472412     Source Type: Journal    
DOI: 10.1093/ehjci/jet274     Document Type: Article

References (31)

1. Saraste A, Kajander S, Han C, Nesterov SV, Knuuti J. PET: Is myocardial flow quantification a clinical reality?. J Nucl Cardiol 2012;19: 1044-59.
2. Uren NG, Melin JA, De Bruyne B, Wijns W, Baudhuin T, Camici PG. Relation between myocardial blood flow and the severity of coronary artery stenosis. N Engl J Med 1994;330: 1782-8.
3. Hutchins GD, Schwaiger M, Rosenspire KC, Krivokapich J, Schelbert H, Kuhl DE. Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomography imaging. J Am Coll Cardiol 1990;15: 1032-42.
4. Lortie M, Beanlands RS, Yoshinaga K, Klein R, Dasilva JN, DeKemp RA. Quantification of myocardial blood flow with 82-Rb dynamic PET imaging. Eur J Nucl Med Mol Imaging 2007;34: 1765-74.
5. Anagnostopoulos C, Almonacid A, El Fakhri G, Curillova Z, Sitek A, Roughton M. Quantitative relationship between coronary vasodilator reserve assessed by 82-Rb PET imaging and coronary artery stenosis severity. Eur J Nucl Med Mol Imaging 2008;35: 1593-601.
6. El Fakhri G, Kardan A, Sitek A, Dorbala S, Abi-Hatem N, Lahoud Y et al. Reproducibility and accuracy of quantitative myocardial blood flow assessment with (82)Rb PET: Comparison with (13)N-ammonia PET. J Nucl Med 2009;50: 1062-71.
7. Lautamaki R, George RT, Kitagawa K, Higuchi T, Merrill J, VoicuCet al. Rubidium-82 PET-CT for quantitative assessment of myocardial blood flow: Validation in a canine model of coronary artery stenosis. Eur J Nucl Med Mol Imaging 2009;36: 576-86.
8. Schindler TH, Schelbert HR, Quercioli A, Dilsizian V. Cardiac PET imaging for the detection and monitoring of coronary artery disease and microvascular health. J Am Coll Cardiol Img 2010;3: 623-40.
9. Parkash R, deKemp RA, Ruddy TD, Kitsikis A, Hart R, Beauchesne L et al. Potential utility of rubidium 82 PET quantification in patients with 3-vessel coronary artery disease. J Nucl Cardiol. 2004;11: 440-9.
10. Yoshinaga K, Katoh C, Noriyasu K, Iwado Y, Furuyama H, Ito Y et al. Reduction of coronary flow reserve in areas with and without ischemia on stress perfusion imaging in patients with coronary artery disease: A study using oxygen 15-labeled water PET. J Nucl Cardiol. 2003;10: 275-83.
11. Muzik O, Duvernoy C, Beanlands RS, Sawada S, Dayanikli F, Wolfe ER Jr et al. Assessment of diagnostic performance of quantitative flow measurements in normal subjects and patients with angiographically documented coronary artery disease by means of nitrogen-13 ammonia and positron emission tomography. J Am Coll Cardiol 1998;31: 534-40.
12. HajjiriMM, Leavitt MB, Zheng H, Spooner AE, Fischman AJ, Gewirtz H. Comparison of positron emission tomography measurement of adenosine-stimulated absolute myocardial blood flow versus relative relative myocardial tracer content for physiological assessment of coronary artery stenosis severity and location. J AmColl Cardiol Img 2009;2: 751-8.
13. Kajander SA, Joutsiniemi E, Saraste M, Pietilä M, Ukkonen H, Saraste A et al. Clinical value of absolute quantification of myocardial perfusion with (15)O-water in coronary artery disease. Circ Cardiovasc Imaging 2011;4: 678-84.
14. Fiechter M, Ghadri JR, Gebhard C, Fuchs TA, Pazhenkottil AP, Nkoulou RN et al. Diagnostic value of 13N-ammonia myocardial perfusion PET: Added value of myocardial flow reserve. J Nucl Med 2012;53: 1230-4.
15. Shaw LJ, Hage FG, Berman DS, Hachamovitch R, Iskandrian A. Prognosis in the era of comparative effectiveness research: Where is nuclear cardiology now and where should it be? J Nucl Cardiol 2012;19: 1026-43.
16. Murthy VL, NayaM, Foster CR, Hainer J, Gaber M, Di CarliGet al. Improved cardiac risk assessment with noninvasive measures of coronary flow reserve. Circulation 2011;124: 2215-24.
17. Gould KL. Assessment of coronary stenoses with myocardial perfusion imaging during pharmacologic coronary vasodilatation. IV. Limits of detection of stenosis with idealized experimental cross-sectional myocardial imaging. Am J Cardiol 1978; 42: 761-8.
18. Czernin J, Müller P, Chan S, Brunken RC, Porenta G, Krivokapich J et al. Influence of age and hemodynamics on myocardial blood flow and flow reserve. Circulation 1993; 88: 62-9.
19. McGinn AL, WhiteCW, Wilson RF. Interstudy variability of coronary flow reserve: Influence of heart rate, arterial blood pressure, and ventricular preload. Circulation 1990;81: 1319-30.
20. Rossen JD, Winniford MD. Effects of increases in heart rate and arterial pressure on coronary flow reserve in humans. J Am Coll Cardiol 1993;21: 343-8.
21. Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al. Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. Eur Heart J 2006;27: 1341-81.
22. Nesterov SV, Han C, Mäki M, Kajander S, Naum AG, Helenius H et al. Myocardial perfusion quantitation with 15O-labelled water PET: High reproducibility of the new cardiac analysis software (CarimasTM). Eur J Nucl Med Mol Imaging 2009;36: 1594-602.
23. Cecchi F, Olivotto I, Gistri R, Lorenzoni R, Chiriatti G, Camici PG. Coronary microvascular dysfunction and prognosis in hypertrophic cardiomyopathy. N Engl J Med 2003;349: 1027-35.
24. Neglia D, Michelassi C, Trivieri MG, Sambuceti G, Giorgetti A, Pratali L et al. Prognostic role of myocardial blood flow impairment in idiopathic left ventricular dysfunction. Circulation 2002;105: 186-93.
25. JohnsonNP, Gould KL. Integrating noninvasive absolute flow,coronaryflowreserve, and ischemic thresholds into a comprehensivemapof physiological severity. J AmColl Cardiol Img 2012;5: 430-40.
26. Kajander S, Joutsiniemi E, Saraste M, Pietilä M, Ukkonen H, Saraste A et al. Cardiac positron emission tomography/computed tomography imaging accurately detects anatomically and functionally significant coronary artery disease. Circulation 2010; 122: 603-13.
27. Hutchins GD, Schwaiger M, Rosenspire KC, Krivokapich J, Schelbert H, Kuhl DE. Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging. J Am Coll Cardiol 1990;15: 1032-42.
28. Bö ttcher M, Czernin J, Sun K, Phelps ME, Schelbert HR. Effect of beta 1 adrenergic receptor blockade on myocardial blood flow and vasodilatory capacity. J Nucl Med 1997;38: 442-6.
29. Ozdemir M, Yazici GE, Turkoglu S, Timurkaynak T, Cengel A. Metoprolol does not effect myocardial fractional flow reserve in patients with intermediate coronary stenosis. Int heart J 2007;48: 477-83.
30. Nekolla SG, Reder S, Saraste A, Higuchi T, Dzewas G, Preissel A et al. Evaluation of the novel myocardial perfusion positron-emission tomography tracer 18F-BMS-747158-02: Comparison to 13N-ammonia and validation with microspheres in a pig model. Circulation 2009;119: 2333-42.
31. Melikian N,DeBondt P, Tonino P,DeWinter O, Wyffels E, Bartunek J et al. Fractional flow reserve and myocardial perfusion imaging in patients with angiographic multivessel coronary artery disease. JACC Cardiovasc Interv 2010;3: 307-14.