메뉴 건너뛰기




Volumn 51, Issue , 2014, Pages 44-50

The role of M3 muscarinic acetylcholine receptor reactive T cells in Sjögren's syndrome: A critical review

Author keywords

Anti M3R antibodies; M3R; M3R induced sialadenitis; M3R reactive T cells; Sj gren's syndrome

Indexed keywords

AUTOANTIGEN; EPITOPE; GAMMA INTERFERON; INTERLEUKIN 17; MUSCARINIC M3 RECEPTOR; RECEPTOR ANTIBODY; SYNTHETIC PEPTIDE; AUTOANTIBODY;

EID: 84901256461     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.12.012     Document Type: Review
Times cited : (48)

References (41)
  • 1
    • 26844506257 scopus 로고    scopus 로고
    • Antimuscarinic antibodies in Sjögren's syndrome
    • Dawson L., Tobin A., Smith P., Gorton T. Antimuscarinic antibodies in Sjögren's syndrome. Arthritis Rheum 2005, 52:2984-2995.
    • (2005) Arthritis Rheum , vol.52 , pp. 2984-2995
    • Dawson, L.1    Tobin, A.2    Smith, P.3    Gorton, T.4
  • 2
    • 8344255696 scopus 로고    scopus 로고
    • Inhibitory effects of autoantibodies on the muscarinic receptors in Sjögren's syndrome
    • Li J., Ha Y.M., Ku N.Y., Choi S.Y., Lee S.J., Oh S.B., et al. Inhibitory effects of autoantibodies on the muscarinic receptors in Sjögren's syndrome. Lab Invest 2004, 84:1430-1438.
    • (2004) Lab Invest , vol.84 , pp. 1430-1438
    • Li, J.1    Ha, Y.M.2    Ku, N.Y.3    Choi, S.Y.4    Lee, S.J.5    Oh, S.B.6
  • 3
    • 34147167536 scopus 로고    scopus 로고
    • Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation
    • Scarselli M., Li B., Kim S.K., Wess J. Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation. JBiol Chem 2007, 282:7385-7396.
    • (2007) JBiol Chem , vol.282 , pp. 7385-7396
    • Scarselli, M.1    Li, B.2    Kim, S.K.3    Wess, J.4
  • 4
    • 77954384996 scopus 로고    scopus 로고
    • Functional role of M3 muscarinic acetylcholine receptor (M3R) reactive T cells and anti-M3R autoantibodies in patients with Sögren's syndrome
    • Sumida T., Tsuboi H., Iizuka M., Nakamura Y., Matsumoto I. Functional role of M3 muscarinic acetylcholine receptor (M3R) reactive T cells and anti-M3R autoantibodies in patients with Sögren's syndrome. Autoimmun Rev 2010, 9:615-617.
    • (2010) Autoimmun Rev , vol.9 , pp. 615-617
    • Sumida, T.1    Tsuboi, H.2    Iizuka, M.3    Nakamura, Y.4    Matsumoto, I.5
  • 5
    • 0026509605 scopus 로고
    • Tcell receptor repertoire of infiltrating T cells in lips of Sjogren's syndrome patients
    • Sumida T., Yonaha F., Maeda T., Tanabe E., Koike T., Tomioka H., et al. Tcell receptor repertoire of infiltrating T cells in lips of Sjogren's syndrome patients. JClin Invest 1992, 89:681-685.
    • (1992) JClin Invest , vol.89 , pp. 681-685
    • Sumida, T.1    Yonaha, F.2    Maeda, T.3    Tanabe, E.4    Koike, T.5    Tomioka, H.6
  • 6
    • 0026541784 scopus 로고
    • Restricted junctional usage of T cell receptor Vβ2 and Vβ13 genes, which are overrepresented on infiltrating T cells in the lips of patients with Sjogren's syndrome
    • Yonaha F., Sumida T., Maeda T., Tomioka H., Koike T., Yoshida S. Restricted junctional usage of T cell receptor Vβ2 and Vβ13 genes, which are overrepresented on infiltrating T cells in the lips of patients with Sjogren's syndrome. Arthritis Rheum 1992, 35:1362-1367.
    • (1992) Arthritis Rheum , vol.35 , pp. 1362-1367
    • Yonaha, F.1    Sumida, T.2    Maeda, T.3    Tomioka, H.4    Koike, T.5    Yoshida, S.6
  • 7
    • 0027290414 scopus 로고
    • Characterization of the primary structure of T cell receptor β chains in cells infiltrating the salivary gland in the sicca syndrome of HIC-1 infection
    • Dwyer E., Itescu S., Winchester R. Characterization of the primary structure of T cell receptor β chains in cells infiltrating the salivary gland in the sicca syndrome of HIC-1 infection. JClin Invest 1993, 92:495-502.
    • (1993) JClin Invest , vol.92 , pp. 495-502
    • Dwyer, E.1    Itescu, S.2    Winchester, R.3
  • 8
    • 0028039978 scopus 로고
    • Infiltrating T cells from patients with primary Sjogern's syndrome express restricted or unrestricted T cell receptor Vβ regions depending on the stage of the disease
    • Legras F., Martin T., Knapp A.-M., Pasquali J.-L. Infiltrating T cells from patients with primary Sjogern's syndrome express restricted or unrestricted T cell receptor Vβ regions depending on the stage of the disease. Eur J Immunol 1994, 24:181-185.
    • (1994) Eur J Immunol , vol.24 , pp. 181-185
    • Legras, F.1    Martin, T.2    Knapp, A.-M.3    Pasquali, J.-L.4
  • 9
    • 0028318921 scopus 로고
    • LA-DR alleles in patients with Sjogren's syndrome over-representing Vβ2 and Vβ13 genes in the labial salivary glands
    • Sumida T., Skamaki T., Yonaha F., Maeda T., Namekawa T., Nawata, et al. LA-DR alleles in patients with Sjogren's syndrome over-representing Vβ2 and Vβ13 genes in the labial salivary glands. Br J Rheumatol 1994, 33:420-424.
    • (1994) Br J Rheumatol , vol.33 , pp. 420-424
    • Sumida, T.1    Skamaki, T.2    Yonaha, F.3    Maeda, T.4    Namekawa, T.5    Nawata6
  • 10
    • 0027935216 scopus 로고
    • Tcell receptor Vα repertoire of infiltrating T cells in labial salivary glands from patients with Sjogren's syndrome
    • Sumida T., Kita Y., Yonaha F., Maeda T., Iwamoto I., Yoshida S. Tcell receptor Vα repertoire of infiltrating T cells in labial salivary glands from patients with Sjogren's syndrome. JRheumatol 1994, 21:1655-1661.
    • (1994) JRheumatol , vol.21 , pp. 1655-1661
    • Sumida, T.1    Kita, Y.2    Yonaha, F.3    Maeda, T.4    Iwamoto, I.5    Yoshida, S.6
  • 11
    • 0028170998 scopus 로고
    • Selective expansion of Vβ families by T cells in the blood and salivary gland infiltrate of patients with primary Sjogren's syndrome
    • Smith M.D., Lamour A., Boylston A., Lancaster F.C., Pennec Y.L., van Agthoven A., et al. Selective expansion of Vβ families by T cells in the blood and salivary gland infiltrate of patients with primary Sjogren's syndrome. JRheumatol 1994, 21:1832-1837.
    • (1994) JRheumatol , vol.21 , pp. 1832-1837
    • Smith, M.D.1    Lamour, A.2    Boylston, A.3    Lancaster, F.C.4    Pennec, Y.L.5    van Agthoven, A.6
  • 12
    • 0031567978 scopus 로고    scopus 로고
    • TCR in Fas-sensitive T ells from labial salivary glands of patients with Sjogren's syndrome
    • Sumida T., Matsumoto I., Murata H., Namekawa T., Matsumura R., Tomioka H., et al. TCR in Fas-sensitive T ells from labial salivary glands of patients with Sjogren's syndrome. JImmunol 1997, 158:1020-1025.
    • (1997) JImmunol , vol.158 , pp. 1020-1025
    • Sumida, T.1    Matsumoto, I.2    Murata, H.3    Namekawa, T.4    Matsumura, R.5    Tomioka, H.6
  • 13
    • 0033227595 scopus 로고    scopus 로고
    • Single cell analysis of T cells infiltrating labial salivary glands from patients with Sjogren's syndrome
    • Matsumoto I., Okada S., Kuraoda K., Iwamoto I., Saito Y., Tokuhisa T., et al. Single cell analysis of T cells infiltrating labial salivary glands from patients with Sjogren's syndrome. Int J Mol Med 1999, 4:519-527.
    • (1999) Int J Mol Med , vol.4 , pp. 519-527
    • Matsumoto, I.1    Okada, S.2    Kuraoda, K.3    Iwamoto, I.4    Saito, Y.5    Tokuhisa, T.6
  • 14
    • 24544471293 scopus 로고    scopus 로고
    • Molecular evidence of antigen-driven Vβ13.2 T cells in the lip biopsies and peripheral blood of anti-52kDa Ro autoantibody positive Sjogren's syndrome patients
    • Furrie E., Doherty M., Kershaw A., Crighton A., Morley K., Kay R. Molecular evidence of antigen-driven Vβ13.2 T cells in the lip biopsies and peripheral blood of anti-52kDa Ro autoantibody positive Sjogren's syndrome patients. Arthritis Rheum 1999, S403.
    • (1999) Arthritis Rheum
    • Furrie, E.1    Doherty, M.2    Kershaw, A.3    Crighton, A.4    Morley, K.5    Kay, R.6
  • 15
    • 0029052264 scopus 로고
    • Diverse T cell receptor β gene usage by infiltrating T cells in the lacrimal glands of Sjogren's syndrome
    • Mizushima N., Kohsaka H., Tsubota K., Saito I., Miyasaka N. Diverse T cell receptor β gene usage by infiltrating T cells in the lacrimal glands of Sjogren's syndrome. Clin Exp Immunol 1995, 101:33-38.
    • (1995) Clin Exp Immunol , vol.101 , pp. 33-38
    • Mizushima, N.1    Kohsaka, H.2    Tsubota, K.3    Saito, I.4    Miyasaka, N.5
  • 16
    • 0029920361 scopus 로고    scopus 로고
    • Common T cell receptor clonotype in lacrimal glands and labial salivary glands from patients with Sjogren's syndrome
    • Matsumoto I., Tsubota K., Satake Y., Kita Y., Matsumura R., Murata H., et al. Common T cell receptor clonotype in lacrimal glands and labial salivary glands from patients with Sjogren's syndrome. JClin Invest 1996, 97:1969-1977.
    • (1996) JClin Invest , vol.97 , pp. 1969-1977
    • Matsumoto, I.1    Tsubota, K.2    Satake, Y.3    Kita, Y.4    Matsumura, R.5    Murata, H.6
  • 17
    • 0029112655 scopus 로고
    • Limited T cell receptor repertoire of infiltrating T cells in the kidneys of Sjogren's syndrome patients with interstitial nephritis
    • Murata H., Kita Y., Sakamoto A., Matsumoto I., Matsumura R., Sugiyama T., et al. Limited T cell receptor repertoire of infiltrating T cells in the kidneys of Sjogren's syndrome patients with interstitial nephritis. JImmunol 1995, 155:4084-4089.
    • (1995) JImmunol , vol.155 , pp. 4084-4089
    • Murata, H.1    Kita, Y.2    Sakamoto, A.3    Matsumoto, I.4    Matsumura, R.5    Sugiyama, T.6
  • 18
    • 0025913673 scopus 로고
    • An abnormal T cell repertoire in hypergammaglobulinemic primary Sjogren's syndrome
    • Kay R.A., Hay E.M., Dyer P.A., Dennett C., Green L.M., Bernstein R.M., et al. An abnormal T cell repertoire in hypergammaglobulinemic primary Sjogren's syndrome. Clin Exp Immunol 1991, 85:262-264.
    • (1991) Clin Exp Immunol , vol.85 , pp. 262-264
    • Kay, R.A.1    Hay, E.M.2    Dyer, P.A.3    Dennett, C.4    Green, L.M.5    Bernstein, R.M.6
  • 19
    • 0028988418 scopus 로고
    • Asubset of Sjogren's syndrome associates with the TCRBV13S2 locus but not the TCRBV2S1 locus
    • Kay R.A., Hutchings C.J., Ollier W.E.R. Asubset of Sjogren's syndrome associates with the TCRBV13S2 locus but not the TCRBV2S1 locus. Hum Immunol 1995, 42:328-330.
    • (1995) Hum Immunol , vol.42 , pp. 328-330
    • Kay, R.A.1    Hutchings, C.J.2    Ollier, W.E.R.3
  • 20
    • 0030474653 scopus 로고    scopus 로고
    • New T cell epitope of Ro/SS-A 52kDa protein in labial salivary glands from patients with Sjogren's syndrome
    • Sumida T., Namekawa T., Maeda T., Nishioka K. New T cell epitope of Ro/SS-A 52kDa protein in labial salivary glands from patients with Sjogren's syndrome. Lancet 1996, 348:1667.
    • (1996) Lancet , vol.348 , pp. 1667
    • Sumida, T.1    Namekawa, T.2    Maeda, T.3    Nishioka, K.4
  • 21
    • 0031444225 scopus 로고    scopus 로고
    • Regulatory T cell epitope recognized by T cells from labial salivary glands of patients with Sjogen's syndrome
    • Sumida T., Kato T., Hasunuma T., Maeda T., Nishioka K., Matsumoto I. Regulatory T cell epitope recognized by T cells from labial salivary glands of patients with Sjogen's syndrome. Arthritis Rheum 1997, 40:2271-2273.
    • (1997) Arthritis Rheum , vol.40 , pp. 2271-2273
    • Sumida, T.1    Kato, T.2    Hasunuma, T.3    Maeda, T.4    Nishioka, K.5    Matsumoto, I.6
  • 22
    • 0033125554 scopus 로고    scopus 로고
    • α-amylase functions as a salivary gland-specific self T cell epitope in patients with Sjogren's syndrome
    • Matsumoto I., Maeda T., Takemoto Y., Hashimoto Y., Kimura F., Iwamoto I., et al. α-amylase functions as a salivary gland-specific self T cell epitope in patients with Sjogren's syndrome. Int J Mol Med 1999, 3:485-490.
    • (1999) Int J Mol Med , vol.3 , pp. 485-490
    • Matsumoto, I.1    Maeda, T.2    Takemoto, Y.3    Hashimoto, Y.4    Kimura, F.5    Iwamoto, I.6
  • 23
    • 31144439287 scopus 로고    scopus 로고
    • Altered peptide ligands regulate muscarinic acetylcholine receptor reactive T cells of patients with Sjogren's syndrome
    • Naito Y., Matsumoto I., Wakamatsu E., Goto D., Ito S., Tsutsumi A., et al. Altered peptide ligands regulate muscarinic acetylcholine receptor reactive T cells of patients with Sjogren's syndrome. Ann Rheum Dis 2005, 65:269-271.
    • (2005) Ann Rheum Dis , vol.65 , pp. 269-271
    • Naito, Y.1    Matsumoto, I.2    Wakamatsu, E.3    Goto, D.4    Ito, S.5    Tsutsumi, A.6
  • 24
    • 84885185085 scopus 로고    scopus 로고
    • Anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjögren's syndrome
    • Sumida T., Tsuboi H., Iizuka M., Asashima H., Matsumoto I. Anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjögren's syndrome. Mod Rheumatol 2013, 23:841-845.
    • (2013) Mod Rheumatol , vol.23 , pp. 841-845
    • Sumida, T.1    Tsuboi, H.2    Iizuka, M.3    Asashima, H.4    Matsumoto, I.5
  • 25
    • 84865977729 scopus 로고    scopus 로고
    • Pathogenic role of anti-M3 muscarinic acetylcholine receptor immune response in Sjögren's syndrome
    • Sumida T., Iizuka M., Asashima H., Tsuboi H., Matsumoto I. Pathogenic role of anti-M3 muscarinic acetylcholine receptor immune response in Sjögren's syndrome. Presse Med 2012, 4:e461-e466.
    • (2012) Presse Med , vol.4
    • Sumida, T.1    Iizuka, M.2    Asashima, H.3    Tsuboi, H.4    Matsumoto, I.5
  • 26
    • 0031593751 scopus 로고    scopus 로고
    • Human primary Sjögren's syndrome autoantibodies as mediators of nitric oxide release coupled to lacrimal gland muscarinic acetylcholine receptors
    • Bacman S.R., Berra A., Sterin-Borda L., Borda E.S. Human primary Sjögren's syndrome autoantibodies as mediators of nitric oxide release coupled to lacrimal gland muscarinic acetylcholine receptors. Curr Eye Res 1998, 17:1135-1142.
    • (1998) Curr Eye Res , vol.17 , pp. 1135-1142
    • Bacman, S.R.1    Berra, A.2    Sterin-Borda, L.3    Borda, E.S.4
  • 27
    • 0033948273 scopus 로고    scopus 로고
    • Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome
    • Waterman S.A., Gordon T.P., Rischmueller M. Inhibitory effects of muscarinic receptor autoantibodies on parasympathetic neurotransmission in Sjögren's syndrome. Arthritis Rheum 2000, 43:1647-1654.
    • (2000) Arthritis Rheum , vol.43 , pp. 1647-1654
    • Waterman, S.A.1    Gordon, T.P.2    Rischmueller, M.3
  • 28
    • 4043140159 scopus 로고    scopus 로고
    • Detection of anti-type 3 muscarinic acetylcholine receptor antibodies in the sera of Sjögren's syndrome patients by use of a transfected cell line assay
    • Gao J., Cha S., Jonsson R., Opalko J., Peck A.B. Detection of anti-type 3 muscarinic acetylcholine receptor antibodies in the sera of Sjögren's syndrome patients by use of a transfected cell line assay. Arthritis Rheum 2004, 50:2615-2621.
    • (2004) Arthritis Rheum , vol.50 , pp. 2615-2621
    • Gao, J.1    Cha, S.2    Jonsson, R.3    Opalko, J.4    Peck, A.B.5
  • 29
    • 14144251323 scopus 로고    scopus 로고
    • Muscarinic acetylcholine receptor autoantibodies in patients with Sjögren's syndrome
    • Naito Y., Matsumoto I., Wakamatsu E., Goto D., Sugiyama T., Matsumura R., et al. Muscarinic acetylcholine receptor autoantibodies in patients with Sjögren's syndrome. Ann Rheum Dis 2005, 64:510-511.
    • (2005) Ann Rheum Dis , vol.64 , pp. 510-511
    • Naito, Y.1    Matsumoto, I.2    Wakamatsu, E.3    Goto, D.4    Sugiyama, T.5    Matsumura, R.6
  • 30
    • 13944255755 scopus 로고    scopus 로고
    • Apeptide of human muscarinic acetylcholine receptor 3 is antigenic in primary Sjögren's syndrome
    • Marczinovits I., Kovacs L., Gyorgy A., Toth G.K., Dorgai L., Molnar J., et al. Apeptide of human muscarinic acetylcholine receptor 3 is antigenic in primary Sjögren's syndrome. JAutoimmun 2005, 24:47-54.
    • (2005) JAutoimmun , vol.24 , pp. 47-54
    • Marczinovits, I.1    Kovacs, L.2    Gyorgy, A.3    Toth, G.K.4    Dorgai, L.5    Molnar, J.6
  • 31
    • 24944481740 scopus 로고    scopus 로고
    • Clinical associations of autoantibodies to human muscarinic acetylcholine receptor 3213-228 in primary Sjögren's syndrome
    • Kovacs L., Marczinovits I., Gyorgy A., Toth G.K., Dorgai L., Pal J., et al. Clinical associations of autoantibodies to human muscarinic acetylcholine receptor 3213-228 in primary Sjögren's syndrome. Rheumatology 2005, 44:1021-1025.
    • (2005) Rheumatology , vol.44 , pp. 1021-1025
    • Kovacs, L.1    Marczinovits, I.2    Gyorgy, A.3    Toth, G.K.4    Dorgai, L.5    Pal, J.6
  • 32
    • 37749048646 scopus 로고    scopus 로고
    • High prevalence of autoantibodies to muscarinic-3 acetylcholine receptor in patients with juvenile-onset Sjögren's syndrome
    • Nakamura Y., Wakamatsu E., Matsumoto I., Tomiita M., Kohno Y., Mori M., et al. High prevalence of autoantibodies to muscarinic-3 acetylcholine receptor in patients with juvenile-onset Sjögren's syndrome. Ann Rheum Dis 2008, 67:136-137.
    • (2008) Ann Rheum Dis , vol.67 , pp. 136-137
    • Nakamura, Y.1    Wakamatsu, E.2    Matsumoto, I.3    Tomiita, M.4    Kohno, Y.5    Mori, M.6
  • 33
    • 77956496706 scopus 로고    scopus 로고
    • New epitopes and function of anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjogren's syndrome
    • Tsuboi H., Matsumoto I., Wakamatsu E., Nakamura Y., Iizuka M., Hayashi T., et al. New epitopes and function of anti-M3 muscarinic acetylcholine receptor antibodies in patients with Sjogren's syndrome. Clin Exp Immunol 2010, 162:53-61.
    • (2010) Clin Exp Immunol , vol.162 , pp. 53-61
    • Tsuboi, H.1    Matsumoto, I.2    Wakamatsu, E.3    Nakamura, Y.4    Iizuka, M.5    Hayashi, T.6
  • 34
    • 84864769771 scopus 로고    scopus 로고
    • The role of muscarinic acetylcholine receptor type 3 polypeptide (M3RP205-220) antibody in the saliva of patients with primary Sjogren's syndrome
    • He J., Qiang L., Ding Y., Wei P., Li Y.N., Hua H., et al. The role of muscarinic acetylcholine receptor type 3 polypeptide (M3RP205-220) antibody in the saliva of patients with primary Sjogren's syndrome. Clin Exp Rheumatol 2012, 30:322-326.
    • (2012) Clin Exp Rheumatol , vol.30 , pp. 322-326
    • He, J.1    Qiang, L.2    Ding, Y.3    Wei, P.4    Li, Y.N.5    Hua, H.6
  • 35
    • 1842505257 scopus 로고    scopus 로고
    • Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome
    • Cavill D., Waterman S.A., Gordon T.P. Antibodies raised against the second extracellular loop of the human muscarinic M3 receptor mimic functional autoantibodies in Sjögren's syndrome. Scand J Immunol 2004, 59:261-266.
    • (2004) Scand J Immunol , vol.59 , pp. 261-266
    • Cavill, D.1    Waterman, S.A.2    Gordon, T.P.3
  • 36
    • 33646343709 scopus 로고    scopus 로고
    • Antimuscarinic antibodies in primary Sjögren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells
    • Dawson L.J., Stanbury J., Venn N., Hasdimir B., Rogers S.N., Smith P.M. Antimuscarinic antibodies in primary Sjögren's syndrome reversibly inhibit the mechanism of fluid secretion by human submandibular salivary acinar cells. Arthritis Rheum 2006, 54:1165-1173.
    • (2006) Arthritis Rheum , vol.54 , pp. 1165-1173
    • Dawson, L.J.1    Stanbury, J.2    Venn, N.3    Hasdimir, B.4    Rogers, S.N.5    Smith, P.M.6
  • 37
    • 44849130374 scopus 로고    scopus 로고
    • Functional epitopes of muscarinic type 3 receptor which interacts with autoantibodies from Sjögren's syndrome patients
    • Koo N.Y., Li J., Hwang S.M., Choi S.Y., Lee S.J., Oh S.B., et al. Functional epitopes of muscarinic type 3 receptor which interacts with autoantibodies from Sjögren's syndrome patients. Rheumatology 2008, 47:828-833.
    • (2008) Rheumatology , vol.47 , pp. 828-833
    • Koo, N.Y.1    Li, J.2    Hwang, S.M.3    Choi, S.Y.4    Lee, S.J.5    Oh, S.B.6
  • 38
    • 84861483947 scopus 로고    scopus 로고
    • Generation and functional analysis of monoclonal antibodies against the second extracellular loop of human M3 muscarinic acetylcholine receptor
    • Tsuboi H., Nakamura Y., Iizuka M., Matsuo N., Matsumoto I., Sumida T. Generation and functional analysis of monoclonal antibodies against the second extracellular loop of human M3 muscarinic acetylcholine receptor. Mod Rheumatol 2012, 22:264-271.
    • (2012) Mod Rheumatol , vol.22 , pp. 264-271
    • Tsuboi, H.1    Nakamura, Y.2    Iizuka, M.3    Matsuo, N.4    Matsumoto, I.5    Sumida, T.6
  • 39
    • 83155163848 scopus 로고    scopus 로고
    • Autoantibodies in primary Sjogren's syndrome patients induce internalization of muscarinic type 3 receptors
    • Jin M., Hwang S.-M., Davies A.J., Shin Y., Bae J.-S., Lee J.-H., et al. Autoantibodies in primary Sjogren's syndrome patients induce internalization of muscarinic type 3 receptors. Biochim Biophys Acta 2012, 1822:161-167.
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 161-167
    • Jin, M.1    Hwang, S.-M.2    Davies, A.J.3    Shin, Y.4    Bae, J.-S.5    Lee, J.-H.6
  • 40
    • 77958150989 scopus 로고    scopus 로고
    • Pathogenic role of immune response to M3 muscarinic acetylcholine receptor in Sjögren's syndrome
    • Iizuka M., Wakamatsu E., Tsuboi H., Nakamura Y., Hayashi T., Matsui M., et al. Pathogenic role of immune response to M3 muscarinic acetylcholine receptor in Sjögren's syndrome. JAutoimmun 2010, 35:383-389.
    • (2010) JAutoimmun , vol.35 , pp. 383-389
    • Iizuka, M.1    Wakamatsu, E.2    Tsuboi, H.3    Nakamura, Y.4    Hayashi, T.5    Matsui, M.6
  • 41
    • 84877773390 scopus 로고    scopus 로고
    • The crucial roles of IFN-γ in the development of M3 muscarinic acetylcholine receptor induced Sjögren's syndrome-like sialadenitis
    • Epub 2012 Oct 26
    • Iizuka M., Tsuboi H., Matuo N., Kondo Y., Asashima H., Matsui M., et al. The crucial roles of IFN-γ in the development of M3 muscarinic acetylcholine receptor induced Sjögren's syndrome-like sialadenitis. Mod Rheumatol 2013, 23:614-616. Epub 2012 Oct 26.
    • (2013) Mod Rheumatol , vol.23 , pp. 614-616
    • Iizuka, M.1    Tsuboi, H.2    Matuo, N.3    Kondo, Y.4    Asashima, H.5    Matsui, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.