Protein tyrosine phosphatase 1B inhibitory activity of lavandulyl flavonoids from roots of Sophora flavescens

Planta Medica

Volumn 80, Issue 7, 2014, Pages 557-560

  Sasaki, Tatsunori ^a   Li, Wei ^a   Higai, Koji ^a   Quang, Tran Hong ^b   Kim, Young Ho ^b   Koike, Kazuo ^a  

^a TOHO UNIVERSITY   (Japan)

^b Chungnam National University   (South Korea)

Author keywords

insulin signaling pathway; lavandulyl flavonoids; Leguminosae; protein tyrosine phosphatase 1B; Sophora flavescens

Indexed keywords

2' METHOXYKURARINONE; FLAVONOID; HYDROLASE INHIBITOR; INSULIN; KURARIDIN; KURARINONE; KUSHENOL T; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 2; NORKURARINONE; PHOSPHOPROTEIN PHOSPHATASE; PLANT MEDICINAL PRODUCT; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 1; PROTEIN TYROSINE PHOSPHATASE SHP 2; RK 682; UNCLASSIFIED DRUG; VACCINIA H1 RELATED PHOSPHATASE; 2'-METHOXYKURARINONE; CHALCONE DERIVATIVE; MOLECULAR LIBRARY; PLANT EXTRACT; PTPN1 PROTEIN, HUMAN; TERPENE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IC 50; KINETICS; LIVER CELL CARCINOMA; PHYTOCHEMISTRY; PLANT ROOT; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SOPHORA FLAVESCENS; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; IC50; ISOLATION AND PURIFICATION; METABOLISM; MOLECULAR LIBRARY; SOPHORA;

FABACEAE; SOPHORA FLAVESCENS;

CHALCONES; FLAVONOIDS; HEP G2 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; INSULIN; KINETICS; MONOTERPENES; PLANT EXTRACTS; PLANT ROOTS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; PROTEIN TYROSINE PHOSPHATASES; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; SOPHORA;

EID: 84901240541     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1368400     Document Type: Article

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