A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness)

Diabetologia

Volumn 57, Issue 6, 2014, Pages 1159-1172

  Strawbridge, Rona J ^a   Deleskog, Anna ^a,b   McLeod, Olga ^a   Folkersen, Lasse ^a   Kavousi, Maryam ^c,d   Gertow, Karl ^a   Baldassarre, Damiano ^e   Veglia, Fabrizio ^e   Leander, Karin ^b   Gigante, Bruna ^b   Kauhanen, Jussi ^f   Rauramaa, Rainer ^f   Smit, Andries J ^d,g   Mannarino, Elmo ^h   Giral, Philippe ⁱ   Dehghan, Abbas ^c,d   Hofman, Albert ^c,d   Franco, Oscar H ^c,d   Humphries, Steve E ^j   Tremoli, Elena ^e   De Faire, Ulf ^b   Gustafsson, Sven ^b   Östensson, Claes Göran ^b   Eriksson, Per ^a   Öhrvik, John ^a   Hamsten, Anders ^a   more..

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d Netherlands Genomics Initiative   (Netherlands)

^e CENTRO CARDIOLOGICO MONZINO   (Italy)

^f UNIVERSITY OF EASTERN FINLAND   (Finland)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^h UNIVERSITY OF PERUGIA   (Italy)

ⁱ ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^j UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

Carotid intima media thickness; Genetic variant; Interaction; Subclinical atherosclerosis; Type 2 diabetes; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; 7 DEHYDROCHOLESTEROL; 7 DEHYDROCHOLESTEROL REDUCTASE; MESSENGER RNA; NAD SYNTHETASE 1; SYNTHETASE; UNCLASSIFIED DRUG; VITAMIN D BINDING PROTEIN; 25-HYDROXYVITAMIN D; 7-DEHYDROCHOLESTEROL REDUCTASE; OXIDOREDUCTASE; VITAMIN D;

ADULT; ADVENTITIA; AORTA ADVENTITIA; ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; COHORT ANALYSIS; CORONARY ARTERY DISEASE; DISEASE MARKER; FEMALE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MENDELIAN RANDOMIZATION ANALYSIS; MOLECULAR INTERACTION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; ULTRASOUND; VITAMIN BLOOD LEVEL; AGED; ANALOGS AND DERIVATIVES; BLOOD; GENETICS; GENOTYPE; MIDDLE AGED;

AGED; CAROTID INTIMA-MEDIA THICKNESS; DIABETES MELLITUS, TYPE 2; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MIDDLE AGED; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; POLYMORPHISM, SINGLE NUCLEOTIDE; VITAMIN D;

EID: 84901236929     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-014-3215-y     Document Type: Article

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