1α,25-Dihydroxyvitamin D3 and its potent synthetic analogs downregulate tissue factor and upregulate thrombomodulin expression in monocytic cells, counteracting the effects of tumor necrosis factor and oxidized LDL

Circulation

Volumn 102, Issue 23, 2000, Pages 2867-2872

  Ohsawa, M ^a   Koyama, T ^a   Yamamoto, K ^a   Hirosawa, S ^a   Kamei, S ^a   Kamiyama, R ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Anticoagulants; Coagulation; Thrombosis

Indexed keywords

22 OXACALCITRIOL; CALCITRIOL; CALCITRIOL DERIVATIVE; THROMBOMODULIN; TUMOR NECROSIS FACTOR; DRUG DERIVATIVE; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA;

ANTICOAGULANT THERAPY; ARTICLE; DRUG EFFECT; DRUG POTENCY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MONOCYTE; PRIORITY JOURNAL; RECEPTOR AFFINITY; THROMBOSIS; TRANSCRIPTION REGULATION; CELL CULTURE; CELL LINE; CELL STRAIN U937; DOWN REGULATION; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

CALCITRIOL; CELL LINE; CELLS, CULTURED; DOWN-REGULATION; HUMANS; LIPOPROTEINS, LDL; MONOCYTES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THROMBOMODULIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS; UP-REGULATION;

EID: 0034610182     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.102.23.2867     Document Type: Article

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