Glucoregulatory function among African Americans and European Americans with normal or pre-diabetic hemoglobin A1c levels

Metabolism: Clinical and Experimental

Volumn 63, Issue 6, 2014, Pages 767-772

  Ebenibo, Sotonte ^a   Edeoga, Chimaroke ^a   Wan, Jim ^a   Dagogo Jack, Samuel ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

A1C; Insulin secretion; Insulin sensitivity; Prediabetes diagnosis; Race Ethnicity

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN;

ADULT; AFRICAN AMERICAN; AGE; ARTICLE; BLOOD SAMPLING; BODY FAT; BODY MASS; CLINICAL ASSESSMENT; CONTROLLED STUDY; DISPOSITION INDEX; EUROPEAN AMERICAN; FAT MASS; FEMALE; GLUCOREGULATORY FUNCTION; GLUCOSE BLOOD LEVEL; GLYCEMIC INDEX; HEMOGLOBIN BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL; RACE DIFFERENCE;

A1C; INSULIN SECRETION; INSULIN SENSITIVITY; PREDIABETES DIAGNOSIS; RACE/ETHNICITY;

ADULT; AFRICAN AMERICANS; AGE FACTORS; AGED; BIOLOGICAL MARKERS; BLOOD GLUCOSE; BODY MASS INDEX; DIAGNOSIS, DIFFERENTIAL; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; PREDIABETIC STATE; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; UNITED STATES;

EID: 84901232032     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2014.03.002     Document Type: Article

References (35)

1. The International Expert Committee International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes Diabetes Care 32 2009 1327 1334
2. American Diabetes Association Diagnosis and classification of diabetes mellitus Diabetes Care 33 Suppl.1 2010 S62 S69
3. Canadian Diabetes Association Definition, classification and diagnosis of diabetes, prediabetes and metabolic syndrome Can J Diabetes 37 Suppl. 1 2013 S8 S12
4. American Diabetes Association Standards of medical care in diabetes - 2014 Diabetes Care 37 Suppl. 1 2014 S14 S16
5. The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus Report of the expert committee on the diagnosis and classification of diabetes mellitus Diabetes Care 20 1997 1183 1197
6. S. Genuth, K.G. Alberti, and P. Bennett et al. Follow-up report on the diagnosis of diabetes mellitus Diabetes Care 26 2003 3160 3167
7. World Health Organization Definition, diagnosis and classification of diabetes mellitus and its complications: report of a WHO consultation. Part 1. Diagnosis and classification of diabetes mellitus 1999 World Health Organization Geneva
8. H.F. Bunn, K.H. Gabbay, and P.M. Gallop The glycosylation of hemoglobin: relevance to diabetes mellitus Science 200 1978 21 27
9. Diabetes Control and Complications Trial Research Group The effect of intensive treatment of diabetes on the development and progression of long term complications in insulin-dependent diabetes mellitus N Engl J Med 329 1993 977 986
10. UK Prospective Diabetes Study Group Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33) Lancet 352 1998 837 853
11. K.T. Khaw, N. Wareham, and S. Bingham et al. Association of hemoglobin A1c with cardiovascular disease and mortality in adults: the European prospective investigation into cancer in Norfolk Ann Intern Med 141 2004 413 420
12. D.B. Sacks, M. Arnold, G.L. Bakris, D.E. Bruns, A.R. Horvath, and M.S. Kirkman et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus Diabetes Care 34 2011 e61 e99 10.2337/dc11-9998
13. S. Dagogo-Jack, C. Edeoga, and E. Nyenwe et al. Pathobiology of prediabetes in a biracial cohort (POP-ABC): design and methods Ethn Dis 21 2011 33 39
14. S. Dagogo-Jack, E. Edeoga, and S. Ebenibo et al. Pathobiology of prediabetes in a biracial cohort (POP-ABC): baseline characteristics of enrolled subjects J Clin Endocrinol Metab 98 2013 120 128
15. D.R. Matthews, J.P. Hosker, and A.S. Rudenski et al. Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
16. C. Weyer, C. Bogardus, and D.M. Mott et al. The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus J Clin Invest 104 1999 787 794
17. R.A. DeFronzo, J.D. Tobin, and R. Andres Glucose clamp technique: a method for quantifying insulin secretion and resistance Am J Physiol 237 1979 E214 E223
18. J.E. Gerich The genetic basis of type 2 diabetes mellitus: impaired insulin secretion versus impaired insulin sensitivity Endocr Rev 19 1998 491 503
19. H. Beck-Nielsen, and L.C. Groop Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus J Clin Invest 94 1994 1714 1721
20. C. Weyer, P.A. Tataranni, and C. Bogardus et al. Insulin resistance and insulin secretory dysfunction are independent predictors of worsening of glucose tolerance during each stage of type 2 diabetes development Diabetes Care 24 2000 89 94
21. G. Bock, C. Dalla Man, and M. Campioni et al. Pathogenesis of pre-diabetes: mechanisms of fasting and postprandial hyperglycemia in people with impaired fasting glucose and/or impaired glucose tolerance Diabetes 55 2006 3536 3549
22. S. Dagogo-Jack, H. Askari, and G. Tykodi Glucoregulatory physiology in subjects with low-normal, high-normal, or impaired fasting glucose J Clin Endocrinol Metab 94 2009 2031 2036
23. M. Kanat, A. Mari, and L. Norton et al. Distinct β-cell defects in impaired fasting glucose and impaired glucose tolerance Diabetes 61 2012 447 453
24. K.C. Chiu, L.M. Chuang, and C. Yoon Comparison of measured and estimated indices of insulin sensitivity and beta cell function: impact of ethnicity on insulin sensitivity and beta cell function in glucose-tolerant and normotensive subjects J Clin Endocrinol Metab 86 2001 1620 1625
25. K. Osei, and D.P. Schuster Ethnic differences in secretion, sensitivity, and hepatic extraction of insulin in black and white Americans Diabet Med 11 1994 755 762
26. M.I. Harris, C.C. Cowie, and K. Gu et al. Higher fasting insulin but lower fasting C-peptide levels in African Americans in the US population Diabetes Metab Res Rev 18 2002 149 155
27. B.J. Gould, S.J. Davie, and J.S. Yudkin Investigation of the mechanism underlying the variability of glycated haemoglobin in non-diabetic subjects not related to glycaemia Clin Chim Acta 260 1997 49 64
28. H. Snieder, P.A. Sawtell, and L. Ross et al. HbA(1c) levels are genetically determined even in type 1 diabetes: evidence from healthy and diabetic twins Diabetes 50 2001 2858 2863
29. P.K. Khera, C.H. Joiner, and A. Carruthers et al. Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation Diabetes 57 2008 2445 2452
30. R.M. Cohen, R.S. Franco, and P.K. Khera et al. Red cell lifespan heterogeneity in hematologically normal people sufficient to alter the apparent HbA1c Blood 112 2008 4284 4291
31. E. Chapp-Jumbo, C. Edeoga, and J. Wan et al. Ethnic disparity in hemoglobin A1c levels among normoglycemic offspring of parents with type 2 diabetes Endocr Pract 18 2012 356 362
32. R.M. Cohen, H. Snieder, and C.J. Lindsell et al. Evidence for independent heritability of the glycation gap (glycosylation gap) fraction of HbA1c in non-diabetic twins Diabetes Care 29 2006 1739 1743
33. S. Dagogo-Jack Pitfalls in the use of HbA1c as a diagnostic test: the ethnic conundrum Nat Rev Endocrinol 6 2010 589 593
34. D.M. Nathan, J. Kuenen, and R. Borg et al. Translating the A1C assay into estimated average glucose values Diabetes Care 31 2008 1473 1478
35. E.S. Kilpatrick, P.W. Maylor, and B.G. Keevil Biological variation of glycated hemoglobin: implications for diabetes screening and monitoring Diabetes Care 21 1998 261 264