PAR2-mediated upregulation of BDNF contributes to central sensitization in bone cancer pain

Molecular Pain

Volumn 10, Issue 1, 2014, Pages

  Bao, Yanju ^a   Hou, Wei ^a   Liu, Rui ^a   Gao, Yebo ^a   Kong, Xiangying ^a   Yang, Liping ^a   Shi, Zhan ^a   Li, Weidong ^a   Zheng, Honggang ^a   Jiang, Shulong ^b   Li, Conghuang ^a   Qin, Yinggang ^a   Hua, Baojin ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b Jining First People's Hospital   (China)

Author keywords

Bone cancer pain; Brain derived neurotrophic factor; Glutamatergic transmission; Nuclear factor B; Proteinase activated receptor 2

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEINASE ACTIVATED RECEPTOR 2;

ADULT; ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE CANCER; CANCER PAIN; CONTROLLED STUDY; FEMALE; GENE ACTIVATION; GLUTAMATERGIC TRANSMISSION; HYPERALGESIA; HYPERSENSITIVITY; NERVE CELL; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SENSITIZATION; SIGNAL TRANSDUCTION; SPINAL CORD DORSAL HORN; TIBIA; TUMOR CELL; TUMOR CELL INOCULATION; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BONE NEOPLASMS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CARCINOMA; DISEASE MODELS, ANIMAL; EXCITATORY AMINO ACID AGENTS; EXCITATORY POSTSYNAPTIC POTENTIALS; FEMALE; HYPERALGESIA; NEOPLASMS, EXPERIMENTAL; NEUROPEPTIDES; NF-KAPPA B; PAIN; RATS; RATS, WISTAR; RECEPTOR, PAR-2; SIGNAL TRANSDUCTION; SPINAL CORD; TIME FACTORS; UP-REGULATION;

EID: 84901231948     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-10-28     Document Type: Article

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