Cationic vesicles based on non-ionic surfactant and synthetic aminolipids mediate delivery of antisense oligonucleotides into mammalian cells

Colloids and Surfaces B: Biointerfaces

Volumn 119, Issue , 2014, Pages 30-37

  Grijalvo, Santiago ^a   Alagia, Adele ^a   Puras, Gustavo ^b   Zárate, Jon ^b   Pedraz, Jose Luis ^b   Eritja, Ramon ^a  

^a INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Antisense oligonucleotide; Antisense therapy; Cationic lipids; Cationic vesicles; Gene delivery; Non ionic surfactant vesicles

Indexed keywords

CELL CULTURE; EMULSIONS; GENE TRANSFER; NUCLEIC ACIDS;

ANTISENSE OLIGONUCLEOTIDES; ANTISENSE THERAPIES; CATIONIC LIPIDS; CATIONIC VESICLES; GENE DELIVERY;

LIPIDS;

ALKYL GROUP; ANTISENSE OLIGONUCLEOTIDE; CATION; DRUG CARRIER; LIPOPLEX; LUCIFERASE; MESSENGER RNA; NONIONIC SURFACTANT; POLYSORBATE 80; SYNTHETIC AMINOLIPID; UNCLASSIFIED DRUG; LIPOSOME; POLYSORBATE; PROPYLAMINE; RENILLA LUCIFERIN 2 MONOOXYGENASE; SURFACTANT;

ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG UPTAKE; ELECTROPHORESIS; GENE EXPRESSION; HUMAN; HUMAN CELL; MAMMAL CELL; MICROMORPHOLOGY; MOLECULAR STABILITY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RENILLA; ZETA POTENTIAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMICAL PHENOMENA; CHEMISTRY; DRUG EFFECTS; GENE TRANSFER; GENETICS; HELA CELL LINE; METABOLISM; SYNTHESIS; TRANSPORT AT THE CELLULAR LEVEL;

BIOLOGICAL TRANSPORT; CATIONS; CELL SURVIVAL; DRUG COMPOUNDING; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HELA CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPOSOMES; LUCIFERASES, RENILLA; OLIGONUCLEOTIDES, ANTISENSE; POLYSORBATES; PROPYLAMINES; RNA, MESSENGER; SURFACE-ACTIVE AGENTS;

EID: 84901218528     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2014.04.016     Document Type: Article

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