Optical hyperpolarization and NMR detection of 129 Xe on a microfluidic chip

Nature Communications

Volumn 5, Issue , 2014, Pages

  Jiménez Martínez, Ricardo ^a,b   Kennedy, Daniel J ^c,d   Rosenbluh, Michael ^e   Donley, Elizabeth A ^a   Knappe, Svenja ^a   Seltzer, Scott J ^c,d   Ring, Hattie L ^c,d   Bajaj, Vikram S ^c,d   Kitching, John ^a  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e BAR ILAN UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRAST MEDIUM; UNCLASSIFIED DRUG; XENON; XENON 129;

MOLECULAR ANALYSIS; NUCLEAR MAGNETIC RESONANCE; OPTICAL PROPERTY; POLARIZATION;

ARTICLE; FLOW RATE; GAS; GAS FLOW; HYPERPOLARIZATION; LAB ON A CHIP; MAGNETIC FIELD; MAGNETOMETRY; MICROFLUIDICS; MICROTECHNOLOGY; NUCLEAR MAGNETIC RESONANCE; POLARIZATION; ROOM TEMPERATURE; EQUIPMENT DESIGN; MICROFLUIDIC ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; SYNTHESIS;

CONTRAST MEDIA; EQUIPMENT DESIGN; MAGNETIC RESONANCE SPECTROSCOPY; MICROFLUIDIC ANALYTICAL TECHNIQUES; XENON ISOTOPES;

EID: 84901207619     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4908     Document Type: Article

References (31)

1. Walker, T. G. & Happer, W. Spin-exchange optical pumping of noble-gas nuclei. Rev. Mod. Phys. 69, 629-642 (1997).
2. Goodson, B. M. Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials, and organisms. J. Magn. Reson. 155, 157-216 (2002).
3. Schroder, L., Lowery, T. J., Hilty, C., Wemmer, D. E. & Pines, A. Molecular imaging using a targeted magnetic resonance hyperpolarized biosensor. Science 314, 446-449 (2006). (Pubitemid 44628961)
4. Schroder, L. Xenon for NMR biosensing- inert but alert. Phys. Med. 29, 3-16 (2013).
5. Mugler, J. & Altes, T. Hyperpolarized Xe MRI of the human lung. J. Magn. Reson. Imaging 37, 313-331 (2013).
6. Whitesides, G. The origins and the future of microfluidics. Nature 442, 368-373 (2006). (Pubitemid 44264779)
7. Driehuys, B. et al. High volume production of laser polarized 129Xe. Appl. Phys. Lett. 69, 1668-1670 (1996).
8. Ruset, I. C., Ketel, S. & Hersman, F. W. Optical pumping system design for large production of hyperpolarized 129Xe. Phys. Rev. Lett. 96, 053002 (2006).
9. Dittrich, P. S. & Manz, A. Lab-on-A-chip: microfluidics in drug discovery. Nat. Rev. Drug Discov. 5, 210-218 (2006). (Pubitemid 43336034)
10. Yager, P. et al. Microfluidic diagnostic technologies for global public health. Nature 442, 412-418 (2006). (Pubitemid 44264785)
11. Knappe, S. et al. Microfabricated atomic clocks and magnetometers. J. Opt. A, Pure Appl. Opt. 8, S318-S322 (2006).
12. Madou, M. J. Fundamentals of Microfabrication: The Science of Miniaturization 2nd edn (CRC Press, 2002).
13. Savukov, I. M. & Romalis, M. V. NMR detection with an atomic magnetometer. Phys. Rev. Lett. 94, 123001 (2005).
14. Harel, E., Schroder, L. & Xu, S. Novel detection schemes of nuclear magnetic resonance and magnetic resonance imaging: applications from analytical chemistry to molecular sensors. Ann. Rev. Anal. Chem. 1, 133-163 (2008).
15. Ledbetter, M. P., Savukov, I., Seltzer, S. J. & Budker, D. Detection of nuclear magnetic resonance with atomic magnetometers. in Optical Magnetometry (eds Budker, D. & Kimball, J.) Chapter 14 (Cambridge University Press, 2013).
16. Bajaj, V. S., Paulsen, J., Harel, E. & Pines, A. Zooming in on microscopic flow by remotely detected MRI. Science 330, 1078-1081 (2010).
17. Jau, Y.-Y., Kizma, N. N. & Happer, W. Measurement of 129Xe-Cs binary spinexchange rate coefficient. Phys. Rev. A 69, 061401 (2004).
18. Grover, B. C. Noble-gas NMR detection through noble-gas-rubidium hyperfine contact interaction. Phys. Rev. Lett. 40, 391-392 (1978).
19. Volk, C. H., Kwon, T. M. & Mark, J. G. Measurement of the 87Rb-129Xe spinexchange cross section. Phys.Rev. A 21, 1549-1555 (1980).
20. Schaefer, S. R. et al. Frequency shifts of the magnetic-resonance spectrum of mixtures of nuclear spin-polarized noble gases and vapors of spin-polarized alkali-metal atoms. Phys. Rev. A 39, 5613-5623 (1989).
21. Herman, R. M. Theory of spin exchange between optically pumped rubidium and foreign gas nuclei. Phys. Rev. 137, A1062-A1065 (1965).
22. Ma, Z. L., Sorte, E. G. & Saam, B. Collisional He and Xe frequency shifts in Rb-noble-gas mixtures. Phys. Rev. Lett. 106, 193005 (2011).
23. Nikolau, P. et al. Near-unity nuclear polarization with an open-source 129Xe hyperpolarizer for NMR and MRI. Proc. Natl Acad. Sci. USA 110, 14150-14155 (2013).
24. Donley, E. A. et al. Nuclear quadrupole resonances in compact vapor cells: the crossover between the NMR and the nuclear quadrupole resonance interaction regimes. Phys. Rev. A 79, 013420 (2009).
25. Donley, E. et al. Microfabricated nuclear magnetic resonance gyroscopes: experimental results from three different instruments with varying levels of miniaturization. Proceedings of the 2009 GOMACTech Conference (2009).
26. Griffith, W. C., Knappe, S. & Kitching, J. Femtotesla atomic magnetometry in a microfabricated vapor cell. Opt. Express 18, 27167-27172 (2010).
27. Ledbetter, M.P. et al. Zero-field remote detection of NMR with a microfabricated atomic magnetometer. Proc. Natl Acad. Sci. USA 105, 2286-2290 (2008). (Pubitemid 351520505)
28. Moule, A. J. et al. Amplification of xenon NMR and MRI by remote detection. Proc. Natl Acad. Sci. USA 100, 9122-9127 (2003). (Pubitemid 37033893)
29. de Jong, J., Geerken, M. J., Lammertink, R. G. H. & Wessling, M. Porous microfluidic devices - fabrication and applications. Chem. Eng. Tech. 30, 309-315 (2007). (Pubitemid 46431627)
30. Levkin, P. A., Svec, F. & Frechet, M. J. Porous polymer coatings: a versatile approach to superhydrophobic surfaces. Adv. Funct. Mat. 19, 1993 (2009).
31. Knappe, S. et al. Atomic vapor cells for chip-scale atomic clocks with improved long-term frequency stability. Opt. Lett. 30, 2351-2353 (2005). (Pubitemid 41463485)