Circulating fetuin-A levels are not affected by short and long-term energy deprivation and/or by leptin administration

Metabolism: Clinical and Experimental

Volumn 63, Issue 6, 2014, Pages 754-759

  Hwang, Janice J ^a   Thakkar, Bindiya ^a,b,c   Chamberland, John P ^a,b   Mantzoros, Christos S ^a,c  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alpha 2 Heremans Schmid glycoprotein; Fetuin A; Leptin

Indexed keywords

FETUIN A; METRELEPTIN; PLACEBO;

ADULT; ARTICLE; BLOOD SAMPLING; BODY COMPOSITION; BODY MASS; CIRCADIAN RHYTHM; COMPARATIVE STUDY; CONTROLLED STUDY; DIET RESTRICTION; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG SELF ADMINISTRATION; ENERGY; ENERGY DEPRIVATION; FEMALE; FOLLICULAR PHASE; HEMATOCRIT; HEPG2 CELL LINE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; INSULIN RESISTANCE; INTERVENTION STUDY; LEPTIN DEFICIENCY; LIPODYSTROPHY; LIVER CELL CARCINOMA; MALE; OBESITY; OPEN STUDY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL;

ALPHA-2-HEREMANS-SCHMID GLYCOPROTEIN; FETUIN-A; LEPTIN;

ADIPOSE TISSUE; ADULT; AGED; ALPHA-2-HS-GLYCOPROTEIN; CALORIC RESTRICTION; FEMALE; HUMANS; LEPTIN; LIVER; MALE; MIDDLE AGED; RNA, MESSENGER; THINNESS; TIME FACTORS;

EID: 84901192239     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2014.02.006     Document Type: Article

References (29)

1. A. Kahraman, J.P. Sowa, M. Schlattjan, S. Sydor, M. Pronadl, and A. Wree et al. Fetuin-A mRNA expression is elevated in NASH compared with NAFL patients Clin Sci 125 2013 391 400
2. S.T. Mathews, G.P. Singh, M. Ranalletta, V.J. Cintron, X. Qiang, and A.S. Goustin et al. Improved insulin sensitivity and resistance to weight gain in mice null for the Ahsg gene Diabetes 51 2002 2450 2458
3. A.M. Hennige, H. Staiger, C. Wicke, F. Machicao, A. Fritsche, and H.U. Haring et al. Fetuin-A induces cytokine expression and suppresses adiponectin production PLoS One 3 2008 1 9 e1765
4. N. Stefan, H.U. Haring, and M.B. Schulze Association of fetuin-A level and diabetes risk JAMA 300 2008 2247 2248
5. N. Stefan, A. Fritsche, C. Weikert, H. Boeing, H.G. Joost, and H.U. Haring et al. Plasma fetuin-A levels and the risk of type 2 diabetes Diabetes 57 2008 2762 2767
6. J.H. Ix, C.L. Wassel, A.M. Kanaya, E. Vittinghoff, K.C. Johnson, and A. Koster et al. Fetuin-A and incident diabetes mellitus in older persons JAMA 300 2008 182 188
7. Q. Sun, M.C. Cornelis, J.E. Manson, and F.B. Hu Plasma levels of fetuin-A and hepatic enzymes and risk of type 2 diabetes in women in the U.S Diabetes 62 2013 49 55
8. K.M. Choi, K.A. Han, H.J. Ahn, S.Y. Lee, S.Y. Hwang, and B.H. Kim et al. The effects of caloric restriction on fetuin-A and cardiovascular risk factors in rats and humans: a randomized controlled trial Clin Endocrinol 79 2013 356 363
9. A. Sahin-Efe, F. Katsikeris, and C.S. Mantzoros Advances in adipokines Metab Clin Exp 61 2012 1659 1665
10. J.P. Warne, J.M. Varonin, S.S. Nielsen, L.E. Olofsson, C.B. Kaelin, and S. Chua Jr. et al. Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein J Neurosci Off J Soc Neurosci 33 2013 11972 11985
11. J. von Schnurbein, M. Heni, A. Moss, S.A. Nagel, J. Machann, and H. Muehleder et al. Rapid improvement of hepatic steatosis after initiation of leptin substitution in a leptin-deficient girl Horm Res Paediatr 79 2013 310 317
12. J.L. Chan, K. Heist, A.M. DePaoli, J.D. Veldhuis, and C.S. Mantzoros The role of falling leptin levels in the neuroendocrine and metabolic adaptation to short-term starvation in healthy men J Clin Invest 111 2003 1409 1421
13. J.L. Chan, G. Matarese, G.K. Shetty, P. Raciti, I. Kelesidis, and D. Aufiero et al. Differential regulation of metabolic, neuroendocrine, and immune function by leptin in humans Proc Natl Acad Sci U S A 103 2006 8481 8486
14. J.L. Chan, S.L. Wong, and C.S. Mantzoros Pharmacokinetics of subcutaneous recombinant methionyl human leptin administration in healthy subjects in the fed and fasting states: regulation by gender and adiposity Clin Pharmacokinet 47 2008 753 764
15. C.K. Welt, J.L. Chan, J. Bullen, R. Murphy, P. Smith, and A.M. DePaoli et al. Recombinant human leptin in women with hypothalamic amenorrhea N Engl J Med 351 2004 987 997
16. K.K. Miller, M.S. Parulekar, E. Schoenfeld, E. Anderson, J. Hubbard, and A. Klibanski et al. Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake J Clin Endocrinol Metab 83 1998 2309 2312
17. M.P. Warren, F. Voussoughian, E.B. Geer, E.P. Hyle, C.L. Adberg, and R.H. Ramos Functional hypothalamic amenorrhea: hypoleptinemia and disordered eating J Clin Endocrinol Metab 84 1999 873 877
18. F.S. Thong, C. McLean, and T.E. Graham Plasma leptin in female athletes: relationship with body fat, reproductive, nutritional, and endocrine factors J Appl Physiol 88 2000 2037 2044
19. G.A. Laughlin, and S.S. Yen Hypoleptinemia in women athletes: absence of a diurnal rhythm with amenorrhea J Clin Endocrinol Metab 82 1997 318 321
20. S.H. Chou, J.P. Chamberland, X. Liu, G. Matarese, C. Gao, and R. Stefanakis et al. Leptin is an effective treatment for hypothalamic amenorrhea Proc Natl Acad Sci U S A 108 2011 6585 6590
21. E. Sienkiewicz, F. Magkos, K.N. Aronis, M. Brinkoetter, J.P. Chamberland, and S. Chou et al. Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women Metab Clin Exp 60 2011 1211 1221
22. J.J. Hwang, J.L. Chan, G. Ntali, D. Malkova, and C.S. Mantzoros Leptin does not directly regulate the pancreatic hormones amylin and pancreatic polypeptide: interventional studies in humans Diabetes Care 31 2008 945 951
23. C.S. Mantzoros, A.D. Liolios, N.A. Tritos, V.G. Kaklamani, D.E. Doulgerakis, and I. Griveas et al. Circulating insulin concentrations, smoking, and alcohol intake are important independent predictors of leptin in young healthy men Obes Res 6 1998 179 186
24. J.P. Foo, and C.S. Mantzoros Leptin in congenital or HIV-associated lipodystrophy and metabolic syndrome: a need for more mechanistic studies and large, randomized, placebo-controlled trials Metab Clin Exp 61 2012 1331 1336
25. S.J. Yang, H.C. Hong, H.Y. Choi, H.J. Yoo, G.J. Cho, and T.G. Hwang et al. Effects of a three-month combined exercise programme on fibroblast growth factor 21 and fetuin-A levels and arterial stiffness in obese women Clin Endocrinol 75 2011 464 469
26. T. Reinehr, and C.L. Roth Fetuin-A and its relation to metabolic syndrome and fatty liver disease in obese children before and after weight loss J Clin Endocrinol Metab 93 2008 4479 4485
27. C.S. Mantzoros Role of leptin in reproduction Ann N Y Acad Sci 900 2000 174 183
28. C.S. Mantzoros, T. Li, J.E. Manson, J.B. Meigs, and F.B. Hu Circulating adiponectin levels are associated with better glycemic control, more favorable lipid profile, and reduced inflammation in women with type 2 diabetes J Clin Endocrinol Metab 90 2005 4542 4548
29. C.S. Mantzoros, S. Moschos, I. Avramopoulos, V. Kaklamani, A. Liolios, and D.E. Doulgerakis et al. Leptin concentrations in relation to body mass index and the tumor necrosis factor-alpha system in humans J Clin Endocrinol Metab 82 1997 3408 3413