Genetically induced oxidative stress in mice causes thrombocytosis, splenomegaly and placental angiodysplasia that leads to recurrent abortion

Redox Biology

Volumn 2, Issue 1, 2014, Pages 679-685

  Ishii, Takamasa ^a   Miyazawa, Masaki ^a,e   Takanashi, Yumi ^a   Tanigawa, Maya ^a   Yasuda, Kayo ^a,b   Onouchi, Hiromi ^a   Kawabe, Noboru ^b   Mitsushita, Junji ^c   Hartman, Phil S ^d   Ishii, Naoaki ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

^d TEXAS CHRISTIAN UNIVERSITY   (United States)

^e NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Abortion; Infertility; Mitochondria; Oxidative stress; SDHC

Indexed keywords

VASCULOTROPIN RECEPTOR 1; MEMBRANE PROTEIN; REACTIVE OXYGEN METABOLITE; SDHC PROTEIN, MOUSE;

ANGIODYSPLASIA; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DELIVERY; EMBRYO DEVELOPMENT; FEMALE; FEMALE FERTILITY; FEMALE INFERTILITY; FETUS DISEASE; GENE MUTATION; HYPOXIA; INFLAMMATION; MALE; MATERNAL MORTALITY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PLACENTA DISORDER; PREGNANCY; PRIORITY JOURNAL; RECURRENT ABORTION; RESPIRATORY CHAIN; SPERMATOGENESIS; SPLENOMEGALY; SPONTANEOUS ABORTION; THROMBOCYTOSIS; TRANSGENIC MOUSE; AMINO ACID SUBSTITUTION; ANIMAL; C57BL MOUSE; GENETICS; METABOLISM; MITOCHONDRION; PATHOLOGY; PLACENTA; PROTEIN CARBONYLATION; FERTILIZATION IN VITRO; GENE; INFERTILITY; OBSTETRIC DELIVERY; OOCYTE DEVELOPMENT; OVARY FUNCTION; PLACENTA ANGIODYSPLASIA; SDHC GENE; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS FUNCTION;

ABORTION, HABITUAL; AMINO ACID SUBSTITUTION; ANGIODYSPLASIA; ANIMALS; FEMALE; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; OXIDATIVE STRESS; PLACENTA; PREGNANCY; PROTEIN CARBONYLATION; REACTIVE OXYGEN SPECIES; SPERMATOGENESIS; SPLENOMEGALY; THROMBOCYTOSIS;

EID: 84901189886     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2014.05.001     Document Type: Article

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