메뉴 건너뛰기




Volumn 54, Issue 4, 2014, Pages 683-690

How Slow RNA Polymerase II Elongation Favors Alternative Exon Skipping

Author keywords

[No Author keywords available]

Indexed keywords

RNA POLYMERASE II;

EID: 84901188097     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.03.044     Document Type: Article
Times cited : (173)

References (40)
  • 5
    • 0035794665 scopus 로고    scopus 로고
    • Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
    • Buratti E., Dörk T., Zuccato E., Pagani F., Romano M., Baralle F.E. Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J. 2001, 20:1774-1784.
    • (2001) EMBO J. , vol.20 , pp. 1774-1784
    • Buratti, E.1    Dörk, T.2    Zuccato, E.3    Pagani, F.4    Romano, M.5    Baralle, F.E.6
  • 6
    • 0025906695 scopus 로고
    • Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium
    • Chu C.S., Trapnell B.C., Murtagh J.J., Moss J., Dalemans W., Jallat S., Mercenier A., Pavirani A., Lecocq J.P., Cutting G.R., et al. Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium. EMBO J. 1991, 10:1355-1363.
    • (1991) EMBO J. , vol.10 , pp. 1355-1363
    • Chu, C.S.1    Trapnell, B.C.2    Murtagh, J.J.3    Moss, J.4    Dalemans, W.5    Jallat, S.6    Mercenier, A.7    Pavirani, A.8    Lecocq, J.P.9    Cutting, G.R.10
  • 8
    • 84876842759 scopus 로고    scopus 로고
    • Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells
    • Danko C.G., Hah N., Luo X., Martins A.L., Core L., Lis J.T., Siepel A., Kraus W.L. Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells. Mol. Cell 2013, 50:212-222.
    • (2013) Mol. Cell , vol.50 , pp. 212-222
    • Danko, C.G.1    Hah, N.2    Luo, X.3    Martins, A.L.4    Core, L.5    Lis, J.T.6    Siepel, A.7    Kraus, W.L.8
  • 9
    • 84875429298 scopus 로고    scopus 로고
    • Reflections on the history of pre-mRNA processing and highlights of current knowledge: a unified picture
    • Darnell J.E. Reflections on the history of pre-mRNA processing and highlights of current knowledge: a unified picture. RNA 2013, 19:443-460.
    • (2013) RNA , vol.19 , pp. 443-460
    • Darnell, J.E.1
  • 11
    • 34250363024 scopus 로고    scopus 로고
    • SR proteins function in coupling RNAP II transcription to pre-mRNA splicing
    • Das R., Yu J., Zhang Z., Gygi M.P., Krainer A.R., Gygi S.P., Reed R. SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Mol. Cell 2007, 26:867-881.
    • (2007) Mol. Cell , vol.26 , pp. 867-881
    • Das, R.1    Yu, J.2    Zhang, Z.3    Gygi, M.P.4    Krainer, A.R.5    Gygi, S.P.6    Reed, R.7
  • 12
    • 78049416081 scopus 로고    scopus 로고
    • Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged
    • David C.J., Manley J.L. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes Dev. 2010, 24:2343-2364.
    • (2010) Genes Dev. , vol.24 , pp. 2343-2364
    • David, C.J.1    Manley, J.L.2
  • 13
    • 33750596100 scopus 로고    scopus 로고
    • RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20
    • de la Mata M., Kornblihtt A.R. RNA polymerase II C-terminal domain mediates regulation of alternative splicing by SRp20. Nat. Struct. Mol. Biol. 2006, 13:973-980.
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 973-980
    • de la Mata, M.1    Kornblihtt, A.R.2
  • 17
    • 0041305816 scopus 로고    scopus 로고
    • Perturbation of transcription elongation influences the fidelity of internal exon inclusion in Saccharomyces cerevisiae
    • Howe K.J., Kane C.M., Ares M. Perturbation of transcription elongation influences the fidelity of internal exon inclusion in Saccharomyces cerevisiae. RNA 2003, 9:993-1006.
    • (2003) RNA , vol.9 , pp. 993-1006
    • Howe, K.J.1    Kane, C.M.2    Ares, M.3
  • 19
    • 79952266577 scopus 로고    scopus 로고
    • Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation
    • Ip J.Y., Schmidt D., Pan Q., Ramani A.K., Fraser A.G., Odom D.T., Blencowe B.J. Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation. Genome Res. 2011, 21:390-401.
    • (2011) Genome Res. , vol.21 , pp. 390-401
    • Ip, J.Y.1    Schmidt, D.2    Pan, Q.3    Ramani, A.K.4    Fraser, A.G.5    Odom, D.T.6    Blencowe, B.J.7
  • 23
    • 33748351186 scopus 로고    scopus 로고
    • Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells
    • Listerman I., Sapra A.K., Neugebauer K.M. Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells. Nat. Struct. Mol. Biol. 2006, 13:815-822.
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 815-822
    • Listerman, I.1    Sapra, A.K.2    Neugebauer, K.M.3
  • 26
    • 0033638283 scopus 로고    scopus 로고
    • Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1
    • Monsalve M., Wu Z., Adelmant G., Puigserver P., Fan M., Spiegelman B.M. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Mol. Cell 2000, 6:307-316.
    • (2000) Mol. Cell , vol.6 , pp. 307-316
    • Monsalve, M.1    Wu, Z.2    Adelmant, G.3    Puigserver, P.4    Fan, M.5    Spiegelman, B.M.6
  • 28
    • 0037044769 scopus 로고    scopus 로고
    • Transcriptional activators differ in their abilities to control alternative splicing
    • Nogués G., Kadener S., Cramer P., Bentley D., Kornblihtt A.R. Transcriptional activators differ in their abilities to control alternative splicing. J. Biol. Chem. 2002, 277:43110-43114.
    • (2002) J. Biol. Chem. , vol.277 , pp. 43110-43114
    • Nogués, G.1    Kadener, S.2    Cramer, P.3    Bentley, D.4    Kornblihtt, A.R.5
  • 29
    • 0034647916 scopus 로고    scopus 로고
    • Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element
    • Pagani F., Buratti E., Stuani C., Romano M., Zuccato E., Niksic M., Giglio L., Faraguna D., Baralle F.E. Splicing factors induce cystic fibrosis transmembrane regulator exon 9 skipping through a nonevolutionary conserved intronic element. J. Biol. Chem. 2000, 275:21041-21047.
    • (2000) J. Biol. Chem. , vol.275 , pp. 21041-21047
    • Pagani, F.1    Buratti, E.2    Stuani, C.3    Romano, M.4    Zuccato, E.5    Niksic, M.6    Giglio, L.7    Faraguna, D.8    Baralle, F.E.9
  • 31
    • 79959450181 scopus 로고    scopus 로고
    • Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation
    • Schmidt U., Basyuk E., Robert M.C., Yoshida M., Villemin J.P., Auboeuf D., Aitken S., Bertrand E. Real-time imaging of cotranscriptional splicing reveals a kinetic model that reduces noise: implications for alternative splicing regulation. J. Cell Biol. 2011, 193:819-829.
    • (2011) J. Cell Biol. , vol.193 , pp. 819-829
    • Schmidt, U.1    Basyuk, E.2    Robert, M.C.3    Yoshida, M.4    Villemin, J.P.5    Auboeuf, D.6    Aitken, S.7    Bertrand, E.8
  • 32
    • 63149192174 scopus 로고    scopus 로고
    • Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing
    • Schor I.E., Rascovan N., Pelisch F., Alló M., Kornblihtt A.R. Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing. Proc. Natl. Acad. Sci. USA 2009, 106:4325-4330.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 4325-4330
    • Schor, I.E.1    Rascovan, N.2    Pelisch, F.3    Alló, M.4    Kornblihtt, A.R.5
  • 33
    • 84882452116 scopus 로고    scopus 로고
    • Intragenic epigenetic changes modulate NCAM alternative splicing in neuronal differentiation
    • Schor I.E., Fiszbein A., Petrillo E., Kornblihtt A.R. Intragenic epigenetic changes modulate NCAM alternative splicing in neuronal differentiation. EMBO J. 2013, 32:2264-2274.
    • (2013) EMBO J. , vol.32 , pp. 2264-2274
    • Schor, I.E.1    Fiszbein, A.2    Petrillo, E.3    Kornblihtt, A.R.4
  • 35
    • 84864390703 scopus 로고    scopus 로고
    • Pre-mRNA splicing in disease and therapeutics
    • Singh R.K., Cooper T.A. Pre-mRNA splicing in disease and therapeutics. Trends Mol. Med. 2012, 18:472-482.
    • (2012) Trends Mol. Med. , vol.18 , pp. 472-482
    • Singh, R.K.1    Cooper, T.A.2
  • 36
    • 70350754211 scopus 로고    scopus 로고
    • Rates of in situ transcription and splicing in large human genes
    • Singh J., Padgett R.A. Rates of in situ transcription and splicing in large human genes. Nat. Struct. Mol. Biol. 2009, 16:1128-1133.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1128-1133
    • Singh, J.1    Padgett, R.A.2
  • 37
    • 78049239924 scopus 로고    scopus 로고
    • Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors
    • Solier S., Barb J., Zeeberg B.R., Varma S., Ryan M.C., Kohn K.W., Weinstein J.N., Munson P.J., Pommier Y. Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors. Cancer Res. 2010, 70:8055-8065.
    • (2010) Cancer Res. , vol.70 , pp. 8055-8065
    • Solier, S.1    Barb, J.2    Zeeberg, B.R.3    Varma, S.4    Ryan, M.C.5    Kohn, K.W.6    Weinstein, J.N.7    Munson, P.J.8    Pommier, Y.9
  • 38
    • 47849130071 scopus 로고    scopus 로고
    • Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I
    • Sordet O., Larochelle S., Nicolas E., Stevens E.V., Zhang C., Shokat K.M., Fisher R.P., Pommier Y. Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I. J. Mol. Biol. 2008, 381:540-549.
    • (2008) J. Mol. Biol. , vol.381 , pp. 540-549
    • Sordet, O.1    Larochelle, S.2    Nicolas, E.3    Stevens, E.V.4    Zhang, C.5    Shokat, K.M.6    Fisher, R.P.7    Pommier, Y.8
  • 40
    • 2342443734 scopus 로고    scopus 로고
    • An intronic polypyrimidine-rich element downstream of the donor site modulates cystic fibrosis transmembrane conductance regulator exon 9 alternative splicing
    • Zuccato E., Buratti E., Stuani C., Baralle F.E., Pagani F. An intronic polypyrimidine-rich element downstream of the donor site modulates cystic fibrosis transmembrane conductance regulator exon 9 alternative splicing. J. Biol. Chem. 2004, 279:16980-16988.
    • (2004) J. Biol. Chem. , vol.279 , pp. 16980-16988
    • Zuccato, E.1    Buratti, E.2    Stuani, C.3    Baralle, F.E.4    Pagani, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.