Characterization of azoxymethane-induced colon tumor metastasis to lung in a mouse model relevant to human sporadic colorectal cancer and evaluation of grape seed extract efficacy

Experimental and Toxicologic Pathology

Volumn 66, Issue 5-6, 2014, Pages 235-242

  Derry, Molly M ^a   Raina, Komal ^a   Agarwal, Rajesh ^a,b   Agarwal, Chapla ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

Biomarkers; Chemoprevention; Colorectal cancer; Grape seed extract; Lung metastasis

Indexed keywords

BIOLOGICAL MARKER; CYTOKERATIN 20; GRAPE SEED EXTRACT; SURFACTANT PROTEIN D; THYROID TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTOR CDX2; ANTINEOPLASTIC AGENT; AZOXYMETHANE;

ADENOCARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFICACY; DRUG SCREENING; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; LUNG NODULE; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; CHEMICALLY INDUCED; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; DRUG EFFECTS; HUMAN; INBRED MOUSE STRAIN; LUNG; LUNG NEOPLASMS; PATHOLOGY; SECONDARY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AZOXYMETHANE; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; DRUG SCREENING ASSAYS, ANTITUMOR; GRAPE SEED EXTRACT; HUMANS; LUNG; LUNG NEOPLASMS; MALE; MICE, INBRED STRAINS;

EID: 84901045742     PISSN: 09402993     EISSN: 16181433     Source Type: Journal    
DOI: 10.1016/j.etp.2014.02.003     Document Type: Article

References (34)

1. Boggaram V. Thyroid transcription factor-1 (TTF-1/Nkx2.1/TITF1) gene regulation in the lung. Clinical Science 2009, 116:27-35.
2. Chao C.L., Chang N.C., Weng C.S., Lee K.R., Kao S.T., Hsu J.C., et al. Grape seed extract ameliorates tumor necrosis factor-alpha-induced inflammatory status of human umbilical vein endothelial cells. European Journal of Nutrition 2011, 50:401-409.
3. Chu P., Wu E., Weiss L.M. Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Modern Pathology 2000, 13:962-972.
4. Derry M.M., Raina K., Balaiya V., Jain A.K., Shrotriya S., Huber K.M., et al. Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. Cancer Prevention Research 2013, 6:625-633.
5. Ding Q., Chang C.J., Xie X., Xia W., Yang J.Y., Wang S.C., et al. APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. Journal of Clinical Investigation 2011, 121:4526-4536.
6. Donigan M., Loh B.D., Norcross L.S., Li S., Williamson P.R., DeJesus S., et al. A metastatic colon cancer model using nonoperative transanal rectal injection. Surgical Endoscopy 2010, 24:642-647.
7. Eich N., Cuomo S.E., Rabovsky J., Vita A.J.A., et al. Bioavailability of epicatechin after consumption of grape seed extract in humans. Experimental biology meeting 2012.
8. Fukutake M., Nakatsugi S., Isoi T., Takahashi M., Ohta T., Mamiya S., et al. Suppressive effects of nimesulide, a selective inhibitor of cyclooxygenase-2, on azoxymethane-induced colon carcinogenesis in mice. Carcinogenesis 1998, 19:1939-1942.
9. Ishihara Y., Matsunaga K., Iijima H., Hasegawa G., Suzuki T., Sato A., et al. The combination of 5-FU, leucovorin and CPT-11 (FOLFIRI) prolongs survival through inhibition of metastasis in an orthotopic model of colon cancer. Anticancer Research 2010, 30:403-408.
10. Kaufmann O., Dietel M. Thyroid transcription factor-1 is the superior immunohistochemical marker for pulmonary adenocarcinomas and large cell carcinomas compared to surfactant proteins A and B. Histopathology 2000, 36:8-16.
11. Kaur M., Agarwal C., Agarwal R. Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products. Journal of Nutrition 2009, 139:1806S-1812S.
12. Kelloff G.J., Boone C.W., Crowell J.A., Nayfield S.G., Hawk E., Malone W.F., et al. Risk biomarkers and current strategies for cancer chemoprevention. Journal of Cellular Biochemistry Supplement 1996, 25:1-14.
13. Kimura S., Hara Y., Pineau T., Fernandez-Salguero P., Fox C.H., Ward J.M., et al. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes & Development 1996, 10:60-69.
14. La V.D., Bergeron C., Gafner S., Grenier D. Grape seed extract suppresses lipopolysaccharide-induced matrix metalloproteinase (MMP) secretion by macrophages and inhibits human MMP-1 and -9 activities. Journal of Periodontology 2009, 80:1875-1882.
15. Migliore L., Migheli F., Spisni R., Coppede F. Genetics, cytogenetics, and epigenetics of colorectal cancer. Journal of Biomedicine & Biotechnology 2011, 7923-7962.
16. Naomoto Y., Kondo H., Tanaka N., Orita K. Novel experimental models of human cancer metastasis in nude mice: lung metastasis, intraabdominal carcinomatosis with ascites, and liver metastasis. Journal of Cancer Research and Clinical Oncology 1987, 113:544-549.
17. Ohe Y. Treatment-related death from chemotherapy and thoracic radiotherapy for advanced cancer. Panminerva Medica 2002, 44:205-212.
18. Okubo T., Hogan B.L. Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. Journal of Biology 2004, 3:11.
19. Rajamanickam S., Agarwal R. Natural products and colon cancer: current status and future prospects. Drug Development Research 2008, 69:460-471.
20. Rosenberg D.W., Giardina C., Tanaka T. Mouse models for the study of colon carcinogenesis. Carcinogenesis 2009, 30:183-196.
21. Samija I., Lukac J., Mubrin M.K., Kirac I., Kovacevic D., Kusic Z. Detection of cytokeratin-20-positive cells in preoperative and postoperative blood samples from colorectal cancer patients by real-time RT-PCR. International Journal of Biological Markers 2013.
22. SEER Cancer Statistics Review, 1975-2010; Bethesda, MD: National Cancer Institute. based on November 2012 SEER data submission, posted to the SEER web site, 2013. http://seer.cancer.gov/csr/1975_2010/.
23. Sirovich I., Konovalova N., Codacci-Pisanelli G., Volkova L.M., Giuliani A., Cicconetti F., et al. Activity of ruboxyl, a nitroxyl derivative of daunorubicin, on experimental models of colorectal cancer metastases. Tumour Biology 1999, 20:270-276.
24. Slack J.M. Intestine in the lung. Journal of Biology 2004, 3:10.
25. Sturm J.W., Magdeburg R., Berger K., Petruch B., Samel S., Bonninghoff R., et al. Influence of TNFA on the formation of liver metastases in a syngenic mouse model. International Journal of Cancer 2003, 107:11-21.
26. Sun J.J., Jing W., Ni Y.Y., Yuan X.J., Zhou H.H., Fan Y.Z. New model of in-situ xenograft lymphangiogenesis by a human colonic adenocarcinoma cell line in nude mice. Asian Pacific Journal of Cancer Prevention: APJCP 2012 2012, 13:2823-2828.
27. Taketo M.M. Reflections on the spread of metastasis to cancer prevention. Cancer Prevention Research 2011, 4:324-328.
28. Van Loon K., Venook A.P. Metastatic colorectal cancer: a curable disease. Oncology (Williston Park) 2012, 26(275-276):82.
29. Velmurugan B., Singh R.P., Agarwal R., Agarwal C. Dietary-feeding of grape seed extract prevents azoxymethane-induced colonic aberrant crypt foci formation in Fischer 344 rats. Molecular Carcinogenesis 2010, 49:641-652.
30. Velmurugan B., Singh R.P., Kaul N., Agarwal R., Agarwal C. Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice. Neoplasia 2010, 12:95-102.
31. Wani Y., Notohara K., Nakatani Y., Matsuzaki A. Aberrant nuclear Cdx2 expression in morule-forming tumours in different organs, accompanied by cytoplasmic reactivity. Histopathology 2009, 55:465-468.
32. Werling R.W., Yaziji H., Bacchi C.E., Gown A.M., CDX2 a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomas. American Journal of Surgical Pathology 2003, 27:303-310.
33. Xu F., Ye Y.J., Liu W., Kong M., He Y., Wang S. Dendritic cell/tumor hybrids enhances therapeutic efficacy against colorectal cancer liver metastasis in SCID mice. Scandinavian Journal of Gastroenterology 2010, 45:707-713.
34. Zhang F., Pao W., Umphress S.M., Jakowlew S.B., Meyer A.M., Dwyer-Nield L.D., et al. Serum levels of surfactant protein D are increased in mice with lung tumors. Cancer Research 2003, 63:5889-5894.