Grape seed extract suppresses lipopolysaccharide-induced matrix metalloproteinase (MMP) secretion by macrophages and inhibits human mmp-1 and -9 activities

Journal of Periodontology

Volumn 80, Issue 11, 2009, Pages 1875-1882

  La, Vu Dang ^a   Bergeron, Chantal ^b   Gafner, Stefan ^b   Grenier, Daniel ^a  

^a UNIVERSITÉ LAVAL   (Canada)

^b Tom's of Maine   (United States)

Author keywords

Lipopolysaccharides; Macrophages; Matrix metalloproteinases; Periodontal diseases; Proanthocyanidins; Vitis vinifera

Indexed keywords

ANTIOXIDANT; COLLAGENASE 3; GELATINASE B; GRAPE SEED EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; LIPOPOLYSACCHARIDE; MATRILYSIN; MATRIX METALLOPROTEINASE; MMP1 PROTEIN, HUMAN; MMP13 PROTEIN, HUMAN; MMP3 PROTEIN, HUMAN; MMP7 PROTEIN, HUMAN; MMP8 PROTEIN, HUMAN; NEUTROPHIL COLLAGENASE; RECOMBINANT PROTEIN; STROMELYSIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR RELA;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ARTICLE; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HUMAN; MACROPHAGE; PHYSIOLOGY; SECRETION; TIME;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; ANTIOXIDANTS; CELLS, CULTURED; GRAPE SEED EXTRACT; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASE 8; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; NF-KAPPA B; RECOMBINANT PROTEINS; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA;

EID: 72349084411     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2009.090251     Document Type: Article

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