Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 20, 2014, Pages 7462-7467

  Longden, Thomas A ^a   Dabertrand, Fabrice ^a   Hill Eubanks, David C ^a   Hammack, Sayamwong E ^b   Nelson, Mark T ^a,c  

^a Departments of Pharmacology   (United Kingdom)

^b UNIVERSITY OF VERMONT   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; MESSENGER RNA; MIFEPRISTONE;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; ASTROCYTE; BRAIN BLOOD FLOW; BRAIN MICROCIRCULATION; BRAIN SLICE; CONTROLLED STUDY; MALE; NERVE CELL; NERVE CELL STIMULATION; NEUROVASCULAR COUPLING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; STRESS; VASODILATATION;

CHRONIC STRESS; LIMBIC SYSTEM; NEUROVASCULAR UNIT; POTASSIUM CHANNELS;

AMYGDALA; ANIMALS; ARTERIOLES; ASTROCYTES; BRAIN; CORTICOSTERONE; GLUCOCORTICOIDS; GLUCOSE; HORMONE ANTAGONISTS; LIMBIC SYSTEM; MALE; MIFEPRISTONE; NEURONS; OXYGEN; PHENOTYPE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; TIME FACTORS; VASODILATION;

EID: 84901045159     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1401811111     Document Type: Article

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