Characterization of the Mammalian Initiation Factor eIF2B Complex as a GDP Dissociation Stimulator Protein

Journal of Biological Chemistry

Volumn 276, Issue 27, 2001, Pages 24697-24703

  Williams, Daniel D ^a,d   Price, Nigel T ^b,e   Loughlin, A Jane ^c,f   Proud, Christopher G ^a,b,c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c UNIVERSITY OF KENT   (United Kingdom)

^d Avidex Ltd   (United Kingdom)

^e HANNAH RESEARCH INSTITUTE   (United Kingdom)

^f OPEN UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; DISSOCIATION; PROTEINS; RNA;

MAMMALIAN INITIATION FACTOR;

BIOCHEMISTRY;

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE DIPHOSPHATE DISSOCIATION STIMULATOR PROTEIN; NUCLEOTIDE; PROTEIN; UNCLASSIFIED DRUG;

ALPHA CHAIN; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; DISSOCIATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; MAMMAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; RNA TRANSLATION; STOICHIOMETRY; CHEMICAL MODEL; CHEMISTRY; METABOLISM; PROTEIN CONFORMATION; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROPHOTOMETRY;

MAMMALIA;

BINDING SITES; EUKARYOTIC INITIATION FACTOR-2B; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANOSINE DIPHOSPHATE; HUMANS; MODELS, CHEMICAL; PROTEIN CONFORMATION; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035816596     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011788200     Document Type: Article

References (41)

1. Hinnebusch, A. G. (2000) in Translational Control of Gene Expression (Sonenberg, N., Hershey, J. W. B., and Mathews, M. B., eds) pp. 185-243, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
2. Webb, B. L. J., and Proud, C. G. (1998) Int. J. Biochem. Cell Biol. 29, 1127-1131
3. Welsh, G. I., Miller, C. M., Loughlin, A. J., Price, N. T., and Proud, C. G. (1998) FEBS Lett. 421, 125-130
4. Dholakia, J. N., and Wahba, A. J. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 51-54
5. Dholakia, J. N., Mueser, T. C., Woodley, C. L., Parkhurst, L. J., and Wahba, A. J. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 6746-6750
6. Singh, L. P., and Wahba, A. J. (1998) Biochem. Biophys. Res. Commun. 217, 616-623
7. Singh, L. P., Aroor, A. R., and Wahba, A. J. (1995) Biochem. Biophys. Res. Commun. 212, 1007-1014
8. Oldfield, S., and Proud, C. G. (1992) Eur. J. Biochem. 208, 73-81
9. Kimball, S. R., and Jefferson, L. S. (1995) Biochem. Biophys. Res. Commun. 212, 1074-1081
10. Bushman, J. L., Foiani, M., Cigan, A. M., Paddon, C. J., and Hinnebusch, A. G. (1993) Mol. Cell. Biol. 13, 4618-4631
11. Cigan, A. M., Bushman, J. L., Boal, T. R., and Hinnebusch, A. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5350-5354
12. Flowers, K. M., Kimball, S. R., Feldhoff, R. C., Hinnebusch, A. G., and Jefferson, L. S. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4274-4278
13. Flowers, K. M., Mellor, H., Matts, R., Kimball, S. R., and Jefferson, L. S. (1996) Biochim. Biophys. Acta 1317, 318-324
14. Price, N. T., Kimball, S. R., Jefferson, L. S., and Proud, C. G. (1996) Biochem. J. 318, 631-636
15. Craddock, B. L., Price, N. T., and Proud, C. G. (1995) Biochem. J. 309, 1009-1014
16. Price, N. T., Mellor, H., Craddock, B. L., Flowers, K. M., Kimball, S. R., Wilmer, T., Jefferson, L. S., and Proud, C. G. (1996) Biochem. J. 318, 637-643
17. Williams, D. D., Pavitt, G. D., and Proud, C. G. (2001) J. Biol. Chem. 276, 3733-3742
18. Fabian, J. R., Kimball, S. R., Heinzinger, N. K., and Jefferson, L. S. (1997) J. Biol. Chem. 272, 12359-12365
19. Pavitt, G. D., Ramaiah, K. V. A., Kimball, S. R., and Hinnebusch, A. G. (1998) Genes Dev. 12, 514-526
20. Gomez, E., and Pavitt, G. D. (2000) Mol. Cell. Biol. 20, 3965-3976
21. Hannig, E. M., and Hinnebusch, A. G. (1988) Mol. Cell. Biol. 8, 4808-4820
22. Kimball, S. R., Fabian, J. R., Pavitt, G. D., Hinnebusch, A. G., and Jefferson, L. S. (1998) J. Biol. Chem. 273, 12841-12845
23. Craddock, B. L., and Proud, C. G. (1996) Biochem. Biophys. Res. Commun. 220, 843-847
24. Rowlands, A. G., Panniers, R., and Henshaw, E. C. (1988) J. Biol. Chem. 263, 5526-5533
25. Hwang, Y. W., and Miller, D. L. (1985) J. Biol. Chem. 260, 11498-11502
26. Klebe, C., Bischoff, F. R., Ponstingl, H., and Wittinghofer, A. (1995) Biochemistry 34, 639-647
27. Klebe, C., Prinz, H., Wittinghofer, A., and Goody, R. S. (1995) Biochemistry 34, 12543-12552
28. Lenzen, C., Cool, R. H., Prinz, H., Kuhlmann, J., and Wittinghofer, A. (1998) Biochemistry 37, 7420-7430
29. Hutchinson, J. P., and Eccleston, J. F. (2000) Biochemistry 39, 11348-11359
30. Dholakia, J. N., and Wahba, A. J. (1989) J. Biol. Chem. 264, 546-550
31. Nika, J., Yang, W., Pavitt, G. D., Hinnebusch, A. G., and Hannig, E. M. (2000) J. Biol. Chem. 275, 26011-26017
32. Dholakia, J. N., Francis, B. R., Haley, B. E., and Wahba, A. J. (1989) J. Biol. Chem. 264, 20638-20642
33. Bommer, U. A., Salimans, M. M., Kurzchalia, T. V., Voorma, H. O., and Karpova, G. G. (1988) Biochem. Int. 16, 549-557
34. Bommer, U. A., and Kurzchalia, T. V. (1989) FEBS Lett. 244, 323-327
35. Hannig, E. M., Cigan, A. M., Freeman, B. A., and Yinzy, T. G. (1993) Mol. Cell. Biol. 13, 506-520
36. Gaspar, N. J., Kinzy, T. G., Scherer, B. J., Humbelin, M., Hershey, J. W., and Merrick, W. C. (1994) J. Biol. Chem. 269, 3415-3422
37. Cherfils, J., and Chardin, P. (1999) Trends Biochem. Sci. 24, 306-311
38. Sprang, S. R., and Coleman, D. E. (1998) Cell 95, 155-158
39. Price, N. T., and Proud, C. G. (1994) Biochimie (Paris) 76, 748-760
40. Dever, T. E., Chen, J. J., Barber, G. N., Cigan, A. M., Feng, L., Donahue, T. F., London, I. M., Katze, M. G., and Hinnebusch, A. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 4616-4620
41. Dever, T. E., Feng, L., Wek, R. C., Cigan, A. M., Donahue, T. F., and Hinnebusch, A. G. (1992) Cell 68, 585-596