메뉴 건너뛰기




Volumn 5 APR, Issue , 2014, Pages

Physiologic and pharmacokinetic changes in pregnancy

Author keywords

Fetus; Pharmacokinetics; Pharmacology; Physiology; Pregnancy

Indexed keywords

ALBUMIN; PLASMA PROTEIN;

EID: 84901035355     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00065     Document Type: Review
Times cited : (338)

References (42)
  • 1
    • 3142778004 scopus 로고    scopus 로고
    • Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism
    • doi: 10.1056/NEJMoa040079
    • Alexander, E. K., Marqusee, E., Lawrence, J., Jarolim, P., Fischer, G. A., and Larsen, P. R. (2004). Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. N. Engl. J. Med. 351, 241-249. doi: 10.1056/NEJMoa040079
    • (2004) N. Engl. J. Med. , vol.351 , pp. 241-249
    • Alexander, E.K.1    Marqusee, E.2    Lawrence, J.3    Jarolim, P.4    Fischer, G.A.5    Larsen, P.R.6
  • 2
    • 25144516296 scopus 로고    scopus 로고
    • Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach
    • doi: 10.2165/00003088-200544100-00001
    • Anderson, G. D. (2005). Pregnancy-induced changes in pharmacokinetics: a mechanistic-based approach. Clin. Pharmacokinet. 44, 989-1008. doi: 10.2165/00003088-200544100-00001
    • (2005) Clin. Pharmacokinet. , vol.44 , pp. 989-1008
    • Anderson, G.D.1
  • 3
    • 84961002731 scopus 로고
    • Hemodynamics at rest and during exercise in normal pregnancy as studied by cardiac catheterization
    • doi: 10.1172/JCI103205
    • Bader, R. A., Bader, M. G., Rose, D. J., and Braunwald, E. (1955). Hemodynamics at rest and during exercise in normal pregnancy as studied by cardiac catheterization. J. Clin. Invest. 34, 1524-1536. doi: 10.1172/JCI103205
    • (1955) J. Clin. Invest. , vol.34 , pp. 1524-1536
    • Bader, R.A.1    Bader, M.G.2    Rose, D.J.3    Braunwald, E.4
  • 5
    • 0021305614 scopus 로고
    • Renal sodium and water handling in pregnancy
    • Barron, W. M., and Lindheimer, M. D. (1984). Renal sodium and water handling in pregnancy. Obstet. Gynecol. Annu. 13, 35-69.
    • (1984) Obstet. Gynecol. Annu. , vol.13 , pp. 35-69
    • Barron, W.M.1    Lindheimer, M.D.2
  • 6
    • 0026003017 scopus 로고
    • When do cardiovascular parameters return to their preconception values?
    • doi: 10.1016/0002-9378(91)90432-Q
    • Capeless, E. L., and Clapp, J. F. (1991). When do cardiovascular parameters return to their preconception values? Am. J. Obstet. Gynecol. 165, 883-886. doi: 10.1016/0002-9378(91)90432-Q
    • (1991) Am. J. Obstet. Gynecol. , vol.165 , pp. 883-886
    • Capeless, E.L.1    Clapp, J.F.2
  • 7
    • 0031960034 scopus 로고    scopus 로고
    • Gastric and duodenal ulcers during pregnancy
    • doi: 10.1016/S0889-8553(05)70352-6
    • Cappell, M., and Garcia, A. (1998). Gastric and duodenal ulcers during pregnancy. Gastroenterol. Clin. North Am. 27, 169-195. doi: 10.1016/S0889-8553(05)70352-6
    • (1998) Gastroenterol. Clin. North Am. , vol.27 , pp. 169-195
    • Cappell, M.1    Garcia, A.2
  • 8
    • 0033844689 scopus 로고    scopus 로고
    • Pregnancy, vascular tone, and maternal hemodynamics: a crucial adaptation
    • doi: 10.1097/00006254-200009000-00023
    • Carbillon, L., Uzan, M., and Uzan, S. (2000). Pregnancy, vascular tone, and maternal hemodynamics: a crucial adaptation. Obstet. Gynecol. Surv. 55, 574-581. doi: 10.1097/00006254-200009000-00023
    • (2000) Obstet. Gynecol. Surv. , vol.55 , pp. 574-581
    • Carbillon, L.1    Uzan, M.2    Uzan, S.3
  • 9
    • 0019801797 scopus 로고
    • Effect of antacids on phenytoin bioavailability
    • doi: 10.1097/00007691-198104000-00003
    • Carter, B. L., Garnett, W. R., Pellock, J. M., Stratton, M. A., and Howell, J. R. (1981). Effect of antacids on phenytoin bioavailability. Ther. Drug. Monit. 3, 333-340. doi: 10.1097/00007691-198104000-00003
    • (1981) Ther. Drug. Monit. , vol.3 , pp. 333-340
    • Carter, B.L.1    Garnett, W.R.2    Pellock, J.M.3    Stratton, M.A.4    Howell, J.R.5
  • 10
    • 0024805803 scopus 로고
    • Central hemodynamic assessment of normal term pregnancy
    • doi: 10.1016/0002-9378(89)90900-9
    • Clark, S. L., Cotton, D. B., Lee, W., Bishop, C., Hill, T., Southwick, J., et al. (1989). Central hemodynamic assessment of normal term pregnancy. Am. J. Obstet. Gynecol. 161, 1439-1442. doi: 10.1016/0002-9378(89)90900-9
    • (1989) Am. J. Obstet. Gynecol. , vol.161 , pp. 1439-1442
    • Clark, S.L.1    Cotton, D.B.2    Lee, W.3    Bishop, C.4    Hill, T.5    Southwick, J.6
  • 12
    • 0003357143 scopus 로고
    • Changes in renal hemodynamics and tubular function induced by normal human pregnancy
    • Davison, J. M., and Dunlop, W. (1984). Changes in renal hemodynamics and tubular function induced by normal human pregnancy. Semin. Nephrol. 4, 198.
    • (1984) Semin. Nephrol. , vol.4 , pp. 198
    • Davison, J.M.1    Dunlop, W.2
  • 14
    • 3543083352 scopus 로고    scopus 로고
    • Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study
    • doi: 10.1212/01.WNL.0000133213.10244.FD
    • de Haan, G., Edelbroek, P., Segers, J., Engelsman, M., Lindhout, D., Devile-Notschaele, M., et al. (2004). Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study. Neurology 63, 571-573. doi: 10.1212/01.WNL.0000133213.10244.FD
    • (2004) Neurology , vol.63 , pp. 571-573
    • de Haan, G.1    Edelbroek, P.2    Segers, J.3    Engelsman, M.4    Lindhout, D.5    Devile-Notschaele, M.6
  • 15
    • 0026481307 scopus 로고
    • Respiratory physiology in pregnancy
    • doi: 10.1016/j.ccm.2010.11.001
    • Elkus, R., and Popovich, J. (1992). Respiratory physiology in pregnancy. Clin. Chest Med. 13, 555-565. doi: 10.1016/j.ccm.2010.11.001
    • (1992) Clin. Chest Med. , vol.13 , pp. 555-565
    • Elkus, R.1    Popovich, J.2
  • 16
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: translating functional genomics into rational therapeutics
    • doi: 10.1126/science.286.5439.487
    • Evans, W. E., and Relling, M. V. (1999). Pharmacogenomics: translating functional genomics into rational therapeutics. Science 286, 487-491. doi: 10.1126/science.286.5439.487
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 17
    • 0034967831 scopus 로고    scopus 로고
    • Physiologic changes in pregnancy and their effect on drug disposition
    • doi: 10.1053/sper.2001.24565
    • Frederiksen, M. C. (2001). Physiologic changes in pregnancy and their effect on drug disposition. Semin. Perinatol. 25, 120-123. doi: 10.1053/sper.2001.24565
    • (2001) Semin. Perinatol. , vol.25 , pp. 120-123
    • Frederiksen, M.C.1
  • 18
    • 0030947645 scopus 로고    scopus 로고
    • The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology
    • doi: 10.1210/edrv.18.3.0300
    • Glinoer, D. (1997). The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocr. Rev. 18, 404-433. doi: 10.1210/edrv.18.3.0300
    • (1997) Endocr. Rev. , vol.18 , pp. 404-433
    • Glinoer, D.1
  • 19
    • 0032811664 scopus 로고    scopus 로고
    • What happens to the normal thyroid during pregnancy?
    • doi: 10.1089/thy.1999.9.631
    • Glinoer, D. (1999). What happens to the normal thyroid during pregnancy? Thyroid 9, 631-635. doi: 10.1089/thy.1999.9.631
    • (1999) Thyroid , vol.9 , pp. 631-635
    • Glinoer, D.1
  • 20
    • 0029951261 scopus 로고    scopus 로고
    • hemostasis during pregnancy and puerperium
    • Hehhgren, M. (1996). hemostasis during pregnancy and puerperium. Hemostasis 26, 244-247.
    • (1996) Hemostasis , vol.26 , pp. 244-247
    • Hehhgren, M.1
  • 21
    • 84984088527 scopus 로고
    • Increase in plasma volume during normal pregnancy
    • doi: 10.1111/j.1471-0528.1963.tb04922.x
    • Hytten, F. E., and Paintin, D. B. (1963). Increase in plasma volume during normal pregnancy. J. Obstet. Gynaecol. Br. Commonw. 70, 402-407. doi: 10.1111/j.1471-0528.1963.tb04922.x
    • (1963) J. Obstet. Gynaecol. Br. Commonw. , vol.70 , pp. 402-407
    • Hytten, F.E.1    Paintin, D.B.2
  • 22
    • 0020433522 scopus 로고
    • The clinical significance of hemodilution during pregnancy
    • doi: 10.1097/00006254-198211000-00001
    • Koller, O. (1982). The clinical significance of hemodilution during pregnancy. Obstet. Gynecol. Surv. 37, 649-652. doi: 10.1097/00006254-198211000-00001
    • (1982) Obstet. Gynecol. Surv. , vol.37 , pp. 649-652
    • Koller, O.1
  • 23
    • 0029004912 scopus 로고
    • Erythropoiesis in pregnancy
    • doi: 10.1515/jpme.1995.23.1-2.39
    • Letsky, E. A. (1995). Erythropoiesis in pregnancy. J. Perinat. Med. 23, 39-45. doi: 10.1515/jpme.1995.23.1-2.39
    • (1995) J. Perinat. Med. , vol.23 , pp. 39-45
    • Letsky, E.A.1
  • 24
    • 0032922072 scopus 로고    scopus 로고
    • Pharmacokinetics during pregnancy: evidence-based maternal dose formulation
    • doi: 10.1016/S0029-7844(98)00444-X
    • Little, B. B. (1999). Pharmacokinetics during pregnancy: evidence-based maternal dose formulation. Obstet. Gynecol. 93, 858-868. doi: 10.1016/S0029-7844(98)00444-X
    • (1999) Obstet. Gynecol. , vol.93 , pp. 858-868
    • Little, B.B.1
  • 25
    • 0030893343 scopus 로고    scopus 로고
    • Clinical biochemistry of pregnancy
    • doi: 10.3109/10408369709038216
    • Lockitch, G. (1997). Clinical biochemistry of pregnancy. Crit. Rev. Clin. Lab. Sci. 34, 67-139. doi: 10.3109/10408369709038216
    • (1997) Crit. Rev. Clin. Lab. Sci. , vol.34 , pp. 67-139
    • Lockitch, G.1
  • 26
    • 33750288727 scopus 로고    scopus 로고
    • Gaps in knowledge in treating pregnant women
    • doi: 10.1016/S1550-8579(06)80205-6
    • Mattison, D., and Zajicek, A. (2006). Gaps in knowledge in treating pregnant women. Gend. Med. 3, 169-182. doi: 10.1016/S1550-8579(06)80205-6
    • (2006) Gend. Med. , vol.3 , pp. 169-182
    • Mattison, D.1    Zajicek, A.2
  • 27
    • 0036632710 scopus 로고    scopus 로고
    • Respiratory function in singleton and twin pregnancy
    • doi: 10.1111/j.1471-0528.2002.01515.x
    • McAuliffe, F., Kametas, N., Costello, J., Rafferty, G. F., Greenough, A., and Nicolaides, K. (2002). Respiratory function in singleton and twin pregnancy. BJOG 109, 765-768. doi: 10.1111/j.1471-0528.2002.01515.x
    • (2002) BJOG , vol.109 , pp. 765-768
    • McAuliffe, F.1    Kametas, N.2    Costello, J.3    Rafferty, G.F.4    Greenough, A.5    Nicolaides, K.6
  • 29
  • 30
    • 0014867936 scopus 로고
    • Transit time in the small intestine in pregnancy
    • doi: 10.1111/j.1471-0528.1970.tb03423.x
    • Parry, E., Shields, R., and Turnbull, A. C. (1970). Transit time in the small intestine in pregnancy. J. Obstet. Gynaecol. Br. Commonw. 77, 900-901. doi: 10.1111/j.1471-0528.1970.tb03423.x
    • (1970) J. Obstet. Gynaecol. Br. Commonw. , vol.77 , pp. 900-901
    • Parry, E.1    Shields, R.2    Turnbull, A.C.3
  • 31
    • 0018572857 scopus 로고
    • Hematologic changes associated with pregnancy
    • doi: 10.1097/00003081-197912000-00002
    • Peck, T. M., and Arias, F. (1979). Hematologic changes associated with pregnancy. Clin. Obstet. Gynecol. 22, 785-798. doi: 10.1097/00003081-197912000-00002
    • (1979) Clin. Obstet. Gynecol. , vol.22 , pp. 785-798
    • Peck, T.M.1    Arias, F.2
  • 32
    • 0000015479 scopus 로고
    • Changes in the blood volume during pregnancy and delivery
    • doi: 10.1097/00000542-196507000-00004
    • Pritchard, J. A. (1965). Changes in the blood volume during pregnancy and delivery. Anesthesiology 26, 394-399. doi: 10.1097/00000542-196507000-00004
    • (1965) Anesthesiology , vol.26 , pp. 394-399
    • Pritchard, J.A.1
  • 33
    • 0023870910 scopus 로고
    • Hydronephrosis during pregnancy: a literature survey
    • doi: 10.1016/0028-2243(88)90130-X
    • Rasmussen, P. E., and Nielse, F. R. (1988). Hydronephrosis during pregnancy: a literature survey. Eur. J. Obstet. Gynaecol. Reprod. Biol. 27, 249-259. doi: 10.1016/0028-2243(88)90130-X
    • (1988) Eur. J. Obstet. Gynaecol. Reprod. Biol. , vol.27 , pp. 249-259
    • Rasmussen, P.E.1    Nielse, F.R.2
  • 34
    • 0024567011 scopus 로고
    • Serial study of factors influencing changes in cardiac output during human pregnancy
    • Robson, S. C., Hunter, S., Boys, R. J., and Dunlop, W. (1989). Serial study of factors influencing changes in cardiac output during human pregnancy. Am. J. Physiol. 256, H1060-H1065.
    • (1989) Am. J. Physiol. , vol.256
    • Robson, S.C.1    Hunter, S.2    Boys, R.J.3    Dunlop, W.4
  • 35
    • 0017699655 scopus 로고
    • Cardiac size and performance during pregnancy estimated with echocardiography
    • doi: 10.1016/0002-9149(77)90068-6
    • Rubler, S., Damani, P., and Pinto, E. (1977). Cardiac size and performance during pregnancy estimated with echocardiography. Am. J. Cardiol. 49, 534-540. doi: 10.1016/0002-9149(77)90068-6
    • (1977) Am. J. Cardiol. , vol.49 , pp. 534-540
    • Rubler, S.1    Damani, P.2    Pinto, E.3
  • 36
    • 0015931697 scopus 로고
    • Lithium and pregnancy: hazards to women given lithium during pregnancy and delivery
    • doi: 10.1136/bmj.2.5859.137
    • Schou, M., Amdisen, A., and Steenstrup, O. R. (1973). Lithium and pregnancy: hazards to women given lithium during pregnancy and delivery. Br. Med. J. 2, 137-138. doi: 10.1136/bmj.2.5859.137
    • (1973) Br. Med. J. , vol.2 , pp. 137-138
    • Schou, M.1    Amdisen, A.2    Steenstrup, O.R.3
  • 37
    • 0037275143 scopus 로고    scopus 로고
    • The influence of sex on pharmacokinetics
    • doi: 10.2165/00003088-200342020-00001
    • Schwartz, J. B. (2003). The influence of sex on pharmacokinetics. Clin. Pharmacokinet. 42, 107-121. doi: 10.2165/00003088-200342020-00001
    • (2003) Clin. Pharmacokinet. , vol.42 , pp. 107-121
    • Schwartz, J.B.1
  • 38
    • 79961124578 scopus 로고    scopus 로고
    • Chronic hypertension in pregnancy
    • doi: 10.1056/NEJMcp0804872
    • Seely, E. W., and Ecker, J. (2011). Chronic hypertension in pregnancy. N. Engl. J. Med. 365, 439-446. doi: 10.1056/NEJMcp0804872
    • (2011) N. Engl. J. Med. , vol.365 , pp. 439-446
    • Seely, E.W.1    Ecker, J.2
  • 39
    • 0000604239 scopus 로고
    • An experimental study of the influence of the endocrine system on the nasal respiratory mucosa
    • doi: 10.1017/S0022215100058746
    • Taylor, M. (1961). An experimental study of the influence of the endocrine system on the nasal respiratory mucosa. J. Laryngol. Otol. 75, 972-977. doi: 10.1017/S0022215100058746
    • (1961) J. Laryngol. Otol. , vol.75 , pp. 972-977
    • Taylor, M.1
  • 40
    • 0020069957 scopus 로고
    • Changes in 2,3-diphosphoglycerate during pregnancy and puerperium in normal women and in beta-thalassemia heterozygous women
    • Tsai, C., and De Leeuw, N. K. (1982). Changes in 2,3-diphosphoglycerate during pregnancy and puerperium in normal women and in beta-thalassemia heterozygous women. Am. J. Obstet. Gynecol. 142, 520-523.
    • (1982) Am. J. Obstet. Gynecol. , vol.142 , pp. 520-523
    • Tsai, C.1    De Leeuw, N.K.2
  • 41
    • 57149119738 scopus 로고    scopus 로고
    • Effect of parity on maternal cardiac function during the first trimester of pregnancy
    • doi: 10.1002/uog.5354
    • Turan, O. M., De Paco, C., Kametas, N., Khaw, A., and Nicolaides, K. H. (2008). Effect of parity on maternal cardiac function during the first trimester of pregnancy. Ultrasound Obstet. Gynecol. 32, 849-854. doi: 10.1002/uog.5354
    • (2008) Ultrasound Obstet. Gynecol. , vol.32 , pp. 849-854
    • Turan, O.M.1    De Paco, C.2    Kametas, N.3    Khaw, A.4    Nicolaides, K.H.5
  • 42
    • 0018886137 scopus 로고
    • Conversion of plasma progesterone to desoxycorticosterone in men, non pregnant, and pregnant women, and adrenalectomized subjects
    • doi: 10.1172/JCI109918
    • Winkel, C. A., Milewich, L., Parker, C. R. Jr., Grizzle, W. E., Blevins, J. K., and Hawkes, K. (1980). Conversion of plasma progesterone to desoxycorticosterone in men, non pregnant, and pregnant women, and adrenalectomized subjects. J. Clin. Invest. 66, 803-812. doi: 10.1172/JCI109918
    • (1980) J. Clin. Invest. , vol.66 , pp. 803-812
    • Winkel, C.A.1    Milewich, L.2    Parker Jr., C.R.3    Grizzle, W.E.4    Blevins, J.K.5    Hawkes, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.