메뉴 건너뛰기




Volumn 2014, Issue , 2014, Pages

Ginseng and anticancer drug combination to improve cancer chemotherapy: A critical review

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DOCETAXEL; DOXORUBICIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; EPIRUBICIN; ETOPOSIDE; FLUOROURACIL; GEMCITABINE; GINSENG EXTRACT; GINSENG POLYSACCHARIDE; GINSENOSIDE; GINSENOSIDE RD; GINSENOSIDE RG 3; HERBACEOUS AGENT; HOMOHARRINGTONINE; IRINOTECAN; MESSENGER RNA; MITOMYCIN; MULTIDRUG RESISTANCE PROTEIN; NAVELBINE; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; VASCULOTROPIN;

EID: 84901024079     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2014/168940     Document Type: Review
Times cited : (79)

References (63)
  • 1
    • 84878303014 scopus 로고    scopus 로고
    • Herb-herb combination for therapeutic enhancement and advancement: Theory, practice and future perspectives
    • Che C. T., Wang Z. J., Chow M. S. S., Lam C. W. K., Herb-herb combination for therapeutic enhancement and advancement: theory, practice and future perspectives. Molecules 2013 18 5125 5141
    • (2013) Molecules , vol.18 , pp. 5125-5141
    • Che, C.T.1    Wang, Z.J.2    Chow, M.S.S.3    Lam, C.W.K.4
  • 2
    • 84894639794 scopus 로고    scopus 로고
    • Overcoming chemotherapy resistance with herbal medicines: Past, present and future perspectives
    • Wang Z. J., Xie C., Huang Y., Lam C. W. K., Chow M. S. S., Overcoming chemotherapy resistance with herbal medicines: past, present and future perspectives. Phytochemistry Reviews 2014 13 1 323 337
    • (2014) Phytochemistry Reviews , vol.13 , Issue.1 , pp. 323-337
    • Wang, Z.J.1    Xie, C.2    Huang, Y.3    Lam, C.W.K.4    Chow, M.S.S.5
  • 3
    • 79955655749 scopus 로고    scopus 로고
    • Chinese herbal medicines as adjuvant treatment during chemo- or radio-therapy for cancer
    • Qi F., Li A., Inagaki Y., Gao J., Li J., Kokudo N., Li X. K., Tang W., Chinese herbal medicines as adjuvant treatment during chemo- or radio-therapy for cancer. BioScience Trends 2010 4 6 297 307
    • (2010) BioScience Trends , vol.4 , Issue.6 , pp. 297-307
    • Qi, F.1    Li, A.2    Inagaki, Y.3    Gao, J.4    Li, J.5    Kokudo, N.6    Li, X.K.7    Tang, W.8
  • 4
    • 0032830802 scopus 로고    scopus 로고
    • The efficacy of ginseng. A systematic review of randomised clinical trials
    • DOI 10.1007/s002280050674
    • Vogler B. K., Pittler M. H., Ernst E., The efficacy of ginseng. A systematic review of randomised clinical trials. European Journal of Clinical Pharmacology 1999 55 8 567 575 2-s2.0-0032830802 10.1007/s002280050674 (Pubitemid 29489202)
    • (1999) European Journal of Clinical Pharmacology , vol.55 , Issue.8 , pp. 567-575
    • Vogler, B.K.1    Pittler, M.H.2    Ernst, E.3
  • 5
    • 69149110615 scopus 로고    scopus 로고
    • Ginseng compounds: An update on their molecular mechanisms and medical applications
    • 2-s2.0-69149110615 10.2174/157016109788340767
    • Lü J., Yao Q., Chen C., Ginseng compounds: an update on their molecular mechanisms and medical applications. Current Vascular Pharmacology 2009 7 3 293 302 2-s2.0-69149110615 10.2174/157016109788340767
    • (2009) Current Vascular Pharmacology , vol.7 , Issue.3 , pp. 293-302
    • Lü, J.1    Yao, Q.2    Chen, C.3
  • 6
    • 0141655182 scopus 로고    scopus 로고
    • 1 (ginseng) and parthenolide (feverfew)
    • DOI 10.1016/S0278-6915(03)00146-7
    • Smolinski A. T., Pestka J. J., Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb1 (ginseng) and parthenolide (feverfew). Food and Chemical Toxicology 2003 41 10 1381 1390 2-s2.0-0141655182 10.1016/S0278-6915(03)00146-7 (Pubitemid 37289187)
    • (2003) Food and Chemical Toxicology , vol.41 , Issue.10 , pp. 1381-1390
    • Smolinski, A.T.1    Pestka, J.J.2
  • 7
    • 0002105414 scopus 로고    scopus 로고
    • Herb sales down 15 percent in mainstream market
    • 51, ARTICLE 69
    • Blumenthal M., Herb sales down 15 percent in mainstream market. HerbalGram 2001 51, article 69
    • (2001) HerbalGram
    • Blumenthal, M.1
  • 8
    • 84865039191 scopus 로고    scopus 로고
    • Ginsenosides as anticancer agents: In vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action
    • Nag S. A., Qin J. J., Wang W., Wang M. H., Wang H., Zhang R., Ginsenosides as anticancer agents: in vitro and in vivo activities, structure-activity relationships, and molecular mechanisms of action. Frontiers in Pharmacology 2012 3 25 1 18
    • (2012) Frontiers in Pharmacology , vol.3 , Issue.25 , pp. 1-18
    • Nag, S.A.1    Qin, J.J.2    Wang, W.3    Wang, M.H.4    Wang, H.5    Zhang, R.6
  • 9
    • 0037116642 scopus 로고    scopus 로고
    • Recent patterns of medication use in the ambulatory adult population of the United States: The Slone survey
    • Kaufman D. W., Kelly J. P., Rosenberg L., Anderson T. E., Mitchell A. A., Recent patterns of medication use in the ambulatory adult population of the United States: the Slone survey. The Journal of the American Medical Association 2002 287 3 337 344 2-s2.0-0037116642 (Pubitemid 34251967)
    • (2002) Journal of the American Medical Association , vol.287 , Issue.3 , pp. 337-344
    • Kaufman, D.W.1    Kelly, J.P.2    Rosenberg, L.3    Anderson, T.E.4    Mitchell, A.A.5
  • 10
    • 0029034101 scopus 로고
    • Preventive effect of ginseng intake against various human cancers: A case-control study on 1987 pairs
    • 2-s2.0-0029034101
    • Yun T., Choi S., Preventive effect of ginseng intake against various human cancers: a case-control study on 1987 pairs. Cancer Epidemiology Biomarkers and Prevention 1995 4 4 401 408 2-s2.0-0029034101
    • (1995) Cancer Epidemiology Biomarkers and Prevention , vol.4 , Issue.4 , pp. 401-408
    • Yun, T.1    Choi, S.2
  • 11
    • 68249155377 scopus 로고    scopus 로고
    • Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice
    • 2-s2.0-68249155377 10.1186/1471-2407-9-250
    • Liu T., Huang Y., Cui D., Huang X., Mao S., Ji L., Song H., Yi C., Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice. BMC Cancer 2009 9, article 250 2-s2.0-68249155377 10.1186/1471-2407-9-250
    • (2009) BMC Cancer , vol.9250
    • Liu, T.1    Huang, Y.2    Cui, D.3    Huang, X.4    Mao, S.5    Ji, L.6    Song, H.7    Yi, C.8
  • 12
    • 73949102761 scopus 로고    scopus 로고
    • Anti-invasion and anti-metastasis effects of ginsenoside Rg3 on the hepatocellular carcinoma cell line
    • Hua H. Q., Shen X. K., Qin S. K., Chen H. Y., Anti-invasion and anti-metastasis effects of ginsenoside Rg3 on the hepatocellular carcinoma cell line. Zhongguo Ai Zheng Za Zhi 2005 15 4 326 330
    • (2005) Zhongguo Ai Zheng Za Zhi , vol.15 , Issue.4 , pp. 326-330
    • Hua, H.Q.1    Shen, X.K.2    Qin, S.K.3    Chen, H.Y.4
  • 13
    • 34948887630 scopus 로고    scopus 로고
    • Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen β receptor
    • DOI 10.1038/sj.bjp.0707359, PII 0707359
    • Leung K. W., Cheung L. W. T., Pon Y. L., Wong R. N. S., Mak N. K., Fan T.-P. P., Au S. C. L., Tombran-Tink J., Wong A. S. T., Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen β receptor. British Journal of Pharmacology 2007 152 2 207 215 2-s2.0-34948887630 10.1038/sj.bjp.0707359 (Pubitemid 47517604)
    • (2007) British Journal of Pharmacology , vol.152 , Issue.2 , pp. 207-215
    • Leung, K.W.1    Cheung, L.W.T.2    Pon, Y.L.3    Wong, R.N.S.4    Mak, N.K.5    Fan, T.-P.P.6    Au, S.C.L.7    Tombran-Tink, J.8    Wong, A.S.T.9
  • 14
    • 34948814000 scopus 로고    scopus 로고
    • A ginseng-derived oestrogen receptor β (ERβ) agonist, Rb1 ginsenoside, attenuates capillary morphogenesis
    • DOI 10.1038/sj.bjp.0707360, PII 0707360
    • Papapetropoulos A., A ginseng-derived oestrogen receptor β (ER β) agonist, Rb1 ginsenoside, attenuates capillary morphogenesis. British Journal of Pharmacology 2007 152 2 172 174 2-s2.0-34948814000 10.1038/sj.bjp.0707360 (Pubitemid 47517605)
    • (2007) British Journal of Pharmacology , vol.152 , Issue.2 , pp. 172-174
    • Papapetropoulos, A.1
  • 15
    • 65549094129 scopus 로고    scopus 로고
    • Asian ginseng enhances the anti-proliferative effect of 5-fluorouracil on human colorectal cancer: Comparison between white and red ginseng
    • 2-s2.0-65549094129 10.1007/s12272-009-1405-9
    • Fishbein A. B., Wang C., Li X., Mehendale S. R., Sun S., Aung H. H., Yuan C., Asian ginseng enhances the anti-proliferative effect of 5-fluorouracil on human colorectal cancer: comparison between white and red ginseng. Archives of Pharmacal Research 2009 32 4 505 513 2-s2.0-65549094129 10.1007/s12272-009-1405- 9
    • (2009) Archives of Pharmacal Research , vol.32 , Issue.4 , pp. 505-513
    • Fishbein, A.B.1    Wang, C.2    Li, X.3    Mehendale, S.R.4    Sun, S.5    Aung, H.H.6    Yuan, C.7
  • 16
    • 84876222590 scopus 로고    scopus 로고
    • Preliminary evaluation of the interactions of Panax ginseng and Salvia miltiorrhiza Bunge with 5-fluorouracil on pharmacokinetics in rats and pharmacodynamics in human cells
    • Gu C. X., Qiao J. P., Zhu M. L., Du J. L., Shang W. H., Yin W., Wang W., Han M., Lu W. D., Preliminary evaluation of the interactions of Panax ginseng and Salvia miltiorrhiza Bunge with 5-fluorouracil on pharmacokinetics in rats and pharmacodynamics in human cells. The American Journal of Chinese Medicine 2013 41 2 443 458
    • (2013) The American Journal of Chinese Medicine , vol.41 , Issue.2 , pp. 443-458
    • Gu, C.X.1    Qiao, J.P.2    Zhu, M.L.3    Du, J.L.4    Shang, W.H.5    Yin, W.6    Wang, W.7    Han, M.8    Lu, W.D.9
  • 17
    • 0042320415 scopus 로고    scopus 로고
    • Panax ginseng: A role in cancer therapy?
    • DOI 10.1177/1534735403251167
    • Chang Y. S., Seo E., Gyllenhaal C., Block K. I., Panax ginseng: a role in cancer therapy? Integrative Cancer Therapies 2003 2 1 13 33 2-s2.0-0042320415 10.1177/1534735403251167 (Pubitemid 37101984)
    • (2003) Integrative Cancer Therapies , vol.2 , Issue.1 , pp. 13-33
    • Chang, Y.S.1    Seo, E.-K.2    Gyllenhaal, C.3    Block, K.I.4
  • 18
    • 84862805840 scopus 로고    scopus 로고
    • Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells
    • 2-s2.0-84859562308 10.1111/j.2042-7158.2012.01463.x
    • Du G., Wang C., Zhang Z., Wen X., Somogyi J., Calway T., He T., Du W., Yuan C., Caspase-mediated pro-apoptotic interaction of panaxadiol and irinotecan in human colorectal cancer cells. Journal of Pharmacy and Pharmacology 2012 64 5 727 734 2-s2.0-84859562308 10.1111/j.2042-7158.2012.01463.x
    • (2012) Journal of Pharmacy and Pharmacology , vol.64 , Issue.5 , pp. 727-734
    • Du, G.1    Wang, C.2    Zhang, Z.3    Wen, X.4    Somogyi, J.5    Calway, T.6    He, T.7    Du, W.8    Yuan, C.9
  • 19
    • 69049106403 scopus 로고    scopus 로고
    • Panaxadiol, a purified ginseng component, enhances the anti-cancer effects of 5-fluorouracil in human colorectal cancer cells
    • 2-s2.0-69049106403 10.1007/s00280-009-0966-0
    • Li X., Wang C., Mehendale S. R., Sun S., Wang Q., Yuan C., Panaxadiol, a purified ginseng component, enhances the anti-cancer effects of 5-fluorouracil in human colorectal cancer cells. Cancer Chemotherapy and Pharmacology 2009 64 6 1097 1104 2-s2.0-69049106403 10.1007/s00280-009-0966-0
    • (2009) Cancer Chemotherapy and Pharmacology , vol.64 , Issue.6 , pp. 1097-1104
    • Li, X.1    Wang, C.2    Mehendale, S.R.3    Sun, S.4    Wang, Q.5    Yuan, C.6
  • 20
    • 0028175024 scopus 로고
    • Potentiation of cytotoxicity of mitomycin C by a polyacetylenic alcohol, panaxytriol
    • 2-s2.0-0028175024 10.1007/s002800050055
    • Matsunaga H., Katano M., Saita T., Yamamoto H., Mori M., Potentiation of cytotoxicity of mitomycin C by a polyacetylenic alcohol, panaxytriol. Cancer Chemotherapy and Pharmacology 1994 33 4 291 297 2-s2.0-0028175024 10.1007/s002800050055
    • (1994) Cancer Chemotherapy and Pharmacology , vol.33 , Issue.4 , pp. 291-297
    • Matsunaga, H.1    Katano, M.2    Saita, T.3    Yamamoto, H.4    Mori, M.5
  • 21
    • 67649361895 scopus 로고    scopus 로고
    • Inhibition of NF- B by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel
    • 2-s2.0-67649361895 10.1007/s12272-009-1515-4
    • Kim S. M., Lee S. Y., Yuk D. Y., Moon D. C., Choi S. S., Kim Y., Han S. B., Oh K., Hong J. T., Inhibition of NF- B by ginsenoside Rg3 enhances the susceptibility of colon cancer cells to docetaxel. Archives of Pharmacal Research 2009 32 5 755 765 2-s2.0-67649361895 10.1007/s12272-009-1515-4
    • (2009) Archives of Pharmacal Research , vol.32 , Issue.5 , pp. 755-765
    • Kim, S.M.1    Lee, S.Y.2    Yuk, D.Y.3    Moon, D.C.4    Choi, S.S.5    Kim, Y.6    Han, S.B.7    Oh, K.8    Hong, J.T.9
  • 22
    • 76549121864 scopus 로고    scopus 로고
    • Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF- B
    • 2-s2.0-76549121864 10.1016/j.ejphar.2009.12.018
    • Kim S. M., Lee S. Y., Cho J. S., Son S. M., Choi S. S., Yun Y. P., Yoo H. S., Yoon D. Y., Oh K., Han S. B., Hong J. T., Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF- B. European Journal of Pharmacology 2010 631 1-3 1 9 2-s2.0-76549121864 10.1016/j.ejphar.2009.12.018
    • (2010) European Journal of Pharmacology , vol.631 , Issue.1-3 , pp. 1-9
    • Kim, S.M.1    Lee, S.Y.2    Cho, J.S.3    Son, S.M.4    Choi, S.S.5    Yun, Y.P.6    Yoo, H.S.7    Yoon, D.Y.8    Oh, K.9    Han, S.B.10    Hong, J.T.11
  • 23
    • 0032889077 scopus 로고    scopus 로고
    • Potentiated effects of total saponins of Panax ginseng on inhibition of leukemic cells by cytotoxic drugs
    • 2-s2.0-0032889077
    • Gao R., Jin J., Niu Y., Potentiated effects of total saponins of Panax ginseng on inhibition of leukemic cells by cytotoxic drugs. Zhongguo Zhong Xi Yi Jie He Za Zhi 1999 19 1 17 19 2-s2.0-0032889077
    • (1999) Zhongguo Zhong Xi Yi Jie He Za Zhi , vol.19 , Issue.1 , pp. 17-19
    • Gao, R.1    Jin, J.2    Niu, Y.3
  • 24
    • 33749451019 scopus 로고    scopus 로고
    • Reduction of cisplatin-induced nephrotoxicity by ginsenosides isolated from processed ginseng in cultured renal tubular cells
    • DOI 10.1248/bpb.29.2051
    • Baek S. H., Piao X. L., Lee U. J., Kim H. Y., Park J. H., Reduction of cisplatin-induced nephrotoxicity by ginsenosides isolated from processed ginseng in cultured renal tubular cells. Biological and Pharmaceutical Bulletin 2006 29 10 2051 2055 2-s2.0-33749451019 10.1248/bpb.29.2051 (Pubitemid 44510808)
    • (2006) Biological and Pharmaceutical Bulletin , vol.29 , Issue.10 , pp. 2051-2055
    • Baek, S.H.1    Piao, X.L.2    Lee, U.J.3    Kim, H.Y.4    Park, J.H.5
  • 25
    • 0035200385 scopus 로고    scopus 로고
    • Role of ginsenoside-Rd in cisplatin-induced renal injury: Special reference to DNA fragmentation
    • DOI 10.1159/000046116
    • Yokozawa T., Dong E., Role of ginsenoside-Rd in cisplatin-induced renal injury: special reference to DNA fragmentation. Nephron 2001 89 4 433 438 2-s2.0-0035200385 10.1159/000046116 (Pubitemid 33135824)
    • (2001) Nephron , vol.89 , Issue.4 , pp. 433-438
    • Yokozawa, T.1    Dong, E.2
  • 26
    • 0037363620 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein-mediated multidrug resistance by protopanaxatriol ginsenosides from Korean red ginseng
    • DOI 10.1055/s-2003-38483
    • Choi C., Kang G., Min Y., Reversal of P-glycoprotein-mediated multidrug resistance by protopanaxatriol ginsenosides from Korean red ginseng. Planta Medica 2003 69 3 235 240 2-s2.0-0037363620 10.1055/s-2003-38483 (Pubitemid 36470128)
    • (2003) Planta Medica , vol.69 , Issue.3 , pp. 235-240
    • Choi, C.-H.1    Kang, G.2    Min, Y.-D.3
  • 27
    • 9744225102 scopus 로고    scopus 로고
    • Enhancement of antitumor effects of paclitaxel (taxol) in combination with red ginseng acidic polysaccharide (RGAP)
    • DOI 10.1055/s-2004-832643
    • Shin M. J., Kim Y. S., Kwak Y. S., Song Y. B., Kim Y. S., Park J. D., Enhancement of antitumor effects of paclitaxel (taxol) in combination with red ginseng acidic polysaccharide (RGAP). Planta Medica 2004 70 11 1033 1038 2-s2.0-9744225102 10.1055/s-2004-832643 (Pubitemid 39587036)
    • (2004) Planta Medica , vol.70 , Issue.11 , pp. 1033-1038
    • Shin, M.J.1    Kim, Y.S.2    Kwak, Y.S.3    Song, Y.B.4    Kim, Y.S.5    Park, J.D.6
  • 28
    • 84878883791 scopus 로고    scopus 로고
    • Chemo-sensitivity enhancing effects of Shengai injection on various chemotherapeutic drugs
    • Miao M., Liu Q., Liu Y. R., Chemo-sensitivity enhancing effects of Shengai injection on various chemotherapeutic drugs. Chinese Traditional and Herbal Drugs 2013 44 7 875 876
    • (2013) Chinese Traditional and Herbal Drugs , vol.44 , Issue.7 , pp. 875-876
    • Miao, M.1    Liu, Q.2    Liu, Y.R.3
  • 29
    • 78650280733 scopus 로고    scopus 로고
    • Effects of Korean ginseng root extract on cisplatin-induced emesis in a rat-pica model
    • 2-s2.0-78650280733 10.1016/j.fct.2010.10.019
    • Raghavendran H. R. B., Rekha S., Shin J., Kim H., Wang J., Park H., Choi M., Cho J., Son C., Effects of Korean ginseng root extract on cisplatin-induced emesis in a rat-pica model. Food and Chemical Toxicology 2011 49 1 215 221 2-s2.0-78650280733 10.1016/j.fct.2010.10.019
    • (2011) Food and Chemical Toxicology , vol.49 , Issue.1 , pp. 215-221
    • Raghavendran, H.R.B.1    Rekha, S.2    Shin, J.3    Kim, H.4    Wang, J.5    Park, H.6    Choi, M.7    Cho, J.8    Son, C.9
  • 31
    • 52649136542 scopus 로고    scopus 로고
    • Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression
    • 2-s2.0-52649136542 10.1007/s12272-001-1282-6
    • Du X. F., Jiang C. Z., Wu C. F., Won E. K., Choung S. Y., Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression. Archives of Pharmacal Research 2008 31 9 1153 1159 2-s2.0-52649136542 10.1007/s12272-001-1282-6
    • (2008) Archives of Pharmacal Research , vol.31 , Issue.9 , pp. 1153-1159
    • Du, X.F.1    Jiang, C.Z.2    Wu, C.F.3    Won, E.K.4    Choung, S.Y.5
  • 32
    • 34948850764 scopus 로고    scopus 로고
    • Chemoprotective and adjuvant effects of immunomodulator ginsan in cyclophosphamide-treated normal and tumor bearing mice
    • Shim J. Y., Han Y., Ahn J. Y., Yun Y. S., Song J., Chemoprotective and adjuvant effects of immunomodulator ginsan in cyclophosphamide-treated normal and tumor bearing mice. International Journal of Immunopathology and Pharmacology 2007 20 3 487 497 2-s2.0-34948850764 (Pubitemid 47531052)
    • (2007) International Journal of Immunopathology and Pharmacology , vol.20 , Issue.3 , pp. 487-497
    • Shim, J.Y.1    Han, Y.2    Ahn, J.Y.3    Yun, Y.S.4    Song, J.Y.5
  • 33
    • 77958193646 scopus 로고    scopus 로고
    • Antitumor activities and immunomodulatory effects of ginseng neutral polysaccharides in combination with 5-fluorouracil
    • 2-s2.0-77958193646
    • Ni W., Zhang X., Wang B., Chen Y., Han H., Fan Y., Zhou Y., Tai G., Antitumor activities and immunomodulatory effects of ginseng neutral polysaccharides in combination with 5-fluorouracil. Journal of Medicinal Food 2010 13 2 270 277 2-s2.0-77958193646
    • (2010) Journal of Medicinal Food , vol.13 , Issue.2 , pp. 270-277
    • Ni, W.1    Zhang, X.2    Wang, B.3    Chen, Y.4    Han, H.5    Fan, Y.6    Zhou, Y.7    Tai, G.8
  • 34
    • 34247365969 scopus 로고    scopus 로고
    • Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis ovarian cancer
    • Xu T., Xin Y., Cui M., Jiang X., Gu L., Inhibitory effect of ginsenoside Rg3 combined with cyclophosphamide on growth and angiogenesis ovarian cancer. Chinese Medical Journal 2007 120 7 584 588 2-s2.0-34247365969 (Pubitemid 46629914)
    • (2007) Chinese Medical Journal , vol.120 , Issue.7 , pp. 584-588
    • Xu, T.-M.1    Xin, Y.2    Cui, M.-H.3    Jiang, X.4    Gu, L.-P.5
  • 35
    • 79951777625 scopus 로고    scopus 로고
    • Panax ginseng: An overview of the clinical evidence
    • 2-s2.0-79951777625 10.5142/jgr.2010.34.4.259
    • Ernst E., Panax ginseng: an overview of the clinical evidence. Journal of Ginseng Research 2010 34 4 259 263 2-s2.0-79951777625 10.5142/jgr.2010.34.4.259
    • (2010) Journal of Ginseng Research , vol.34 , Issue.4 , pp. 259-263
    • Ernst, E.1
  • 36
    • 33644618424 scopus 로고    scopus 로고
    • Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma
    • DOI 10.1016/j.bbrc.2006.02.044, PII S0006291X0600341X
    • Zhang Q., Kang X., Zhao W., Antiangiogenic effect of low-dose cyclophosphamide combined with ginsenoside Rg3 on Lewis lung carcinoma. Biochemical and Biophysical Research Communications 2006 342 3 824 828 2-s2.0-33644618424 10.1016/j.bbrc.2006.02.044 (Pubitemid 43320472)
    • (2006) Biochemical and Biophysical Research Communications , vol.342 , Issue.3 , pp. 824-828
    • Zhang, Q.1    Kang, X.2    Zhao, W.3
  • 38
    • 33746665300 scopus 로고    scopus 로고
    • Experimental study on effects of shengmai injection: Enhancing 5-FU anti-tumor efficacy and reducing its toxicity
    • 2-s2.0-33746665300
    • Chen Z., Wang P., Huang W., Liu L., Experimental study on effects of shengmai injection: enhancing 5-FU anti-tumor efficacy and reducing its toxicity. Journal of Chinese Integrative Medicine 2005 3 6 476 479 2-s2.0-33746665300
    • (2005) Journal of Chinese Integrative Medicine , vol.3 , Issue.6 , pp. 476-479
    • Chen, Z.1    Wang, P.2    Huang, W.3    Liu, L.4
  • 39
    • 84891808062 scopus 로고    scopus 로고
    • Effect of Shengmai injection on diaphragmatic contractility in doxorubicin-treated rats
    • Ge M., Fang Y. Y., Liu G. P., Guan S. D., Effect of Shengmai injection on diaphragmatic contractility in doxorubicin-treated rats. Chinese Journal of Integrative Medicine 2014 20 1 43 48
    • (2014) Chinese Journal of Integrative Medicine , vol.20 , Issue.1 , pp. 43-48
    • Ge, M.1    Fang, Y.Y.2    Liu, G.P.3    Guan, S.D.4
  • 40
    • 73849130756 scopus 로고    scopus 로고
    • Effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer
    • 2-s2.0-73849130756 10.1007/s11655-009-0415-2
    • Chen Y., Li Z., Gao F., Zhang Y., Sun H., Li P., Effects of combined Chinese drugs and chemotherapy in treating advanced non-small cell lung cancer. Chinese Journal of Integrative Medicine 2009 15 6 415 419 2-s2.0-73849130756 10.1007/s11655-009-0415-2
    • (2009) Chinese Journal of Integrative Medicine , vol.15 , Issue.6 , pp. 415-419
    • Chen, Y.1    Li, Z.2    Gao, F.3    Zhang, Y.4    Sun, H.5    Li, P.6
  • 41
    • 84901056751 scopus 로고    scopus 로고
    • Effect of Shengmai injection "sandwich" infusion to prevent patients with chemotherapy induced phlebitis
    • Yan A. Y., Guo S. J., Yi Y. J., Effect of Shengmai injection "Sandwich" infusion to prevent patients with chemotherapy induced phlebitis. Chinese Nursing Research 2004 18 20 1859 1860
    • (2004) Chinese Nursing Research , vol.18 , Issue.20 , pp. 1859-1860
    • Yan, A.Y.1    Guo, S.J.2    Yi, Y.J.3
  • 42
    • 84901052379 scopus 로고    scopus 로고
    • The clinic research of the effect of SHENG MAI injection combined with the chemotherapy in the elderly patients with advanced gastric cancer
    • Zhao Z., Liao Z. J., Zhao X. H., The clinic research of the effect of SHENG MAI injection combined with the chemotherapy in the elderly patients with advanced gastric cancer. Journal of Mordern Oncology 2005 13 3 387 388
    • (2005) Journal of Mordern Oncology , vol.13 , Issue.3 , pp. 387-388
    • Zhao, Z.1    Liao, Z.J.2    Zhao, X.H.3
  • 43
    • 84870294113 scopus 로고    scopus 로고
    • Therapeutic efficacy of traditional Chinese medicine, Shen-Mai San, in cancer patients undergoing chemotherapy or radiotherapy: Study protocol for randomized, double-blind, placebo-controlled trial
    • Lo L. C., Chen C. Y., Chen S. T., Chen H. C., Lee T. C., Chang C. S., Therapeutic efficacy of traditional Chinese medicine, Shen-Mai San, in cancer patients undergoing chemotherapy or radiotherapy: study protocol for randomized, double-blind, placebo-controlled trial. Trials 2012 13, article 232
    • (2012) Trials , vol.13
    • Lo, L.C.1    Chen, C.Y.2    Chen, S.T.3    Chen, H.C.4    Lee, T.C.5    Chang, C.S.6
  • 44
    • 27644460611 scopus 로고    scopus 로고
    • Clinical phase II study on immunoimprovement of patients with breast cancer treated by Shengyi capsule
    • Liu J. W., Sun L. X., Zhao Y., Clinical phase II study on immunoimprovement of patients with breast cancer treated by Shengyi capsule. Chinese Journal of Clinical Oncology 2000 27 7 534 544
    • (2000) Chinese Journal of Clinical Oncology , vol.27 , Issue.7 , pp. 534-544
    • Liu, J.W.1    Sun, L.X.2    Zhao, Y.3
  • 45
    • 33745736315 scopus 로고    scopus 로고
    • A randomized, prospective, multi-centre clinical trial of NP regimen (vinorelbine+cisplatin) plus Gensing Rg3 in the treatment of advanced non-small cell lung cancer patients
    • Sun Y., Zhu H., Zhu Y., Feng J., Chen Z., Li G., Zhang X., Zhang Z., Tang J., Shi M., Hao X., Han H., A randomized, prospective, multi-centre clinical trial of NP regimen (vinorelbine+cisplatin) plus Gensing Rg3 in the treatment of advanced non-small cell lung cancer patients. Chinese Journal of Lung Cancer 2006 9 3 254 258 2-s2.0-33745736315 (Pubitemid 44013527)
    • (2006) Chinese Journal of Lung Cancer , vol.9 , Issue.3 , pp. 254-258
    • Sun, Y.1    Zhu, H.2    Zhu, Y.3    Feng, J.4    Chen, Z.5    Li, G.6    Zhang, X.7    Zhang, Z.8    Tang, J.9    Shi, M.10    Hao, X.11    Han, H.12
  • 46
    • 73949087913 scopus 로고    scopus 로고
    • Efficacy of Shenyi Capsule combined with gemcitabine plus cisplatin in treatment of advanced esophageal cancer: A randomized controlled trial
    • 2-s2.0-73949087913 10.3736/jcim20091105
    • Huang J., Sun Y., Fan Q., Zhang Y., Efficacy of Shenyi Capsule combined with gemcitabine plus cisplatin in treatment of advanced esophageal cancer: a randomized controlled trial. Journal of Chinese Integrative Medicine 2009 7 11 1047 1051 2-s2.0-73949087913 10.3736/jcim20091105
    • (2009) Journal of Chinese Integrative Medicine , vol.7 , Issue.11 , pp. 1047-1051
    • Huang, J.1    Sun, Y.2    Fan, Q.3    Zhang, Y.4
  • 47
    • 0036283370 scopus 로고    scopus 로고
    • Panax ginseng: A systematic review of adverse effects and drug interactions
    • Coon J. T., Ernst E., Panax ginseng: a systematic review of adverse effects and drug interactions. Drug Safety 2002 25 5 323 344 2-s2.0-0036283370 (Pubitemid 34634271)
    • (2002) Drug Safety , vol.25 , Issue.5 , pp. 323-344
    • Coon, J.T.1    Ernst, E.2
  • 48
    • 80053535953 scopus 로고    scopus 로고
    • Metabolism of ginseng and its interactions with drugs
    • 2-s2.0-80053535953
    • Qi L., Wang C., Du G., Zhang Z., Calway T., Yuan C., Metabolism of ginseng and its interactions with drugs. Current Drug Metabolism 2011 12 9 818 822 2-s2.0-80053535953
    • (2011) Current Drug Metabolism , vol.12 , Issue.9 , pp. 818-822
    • Qi, L.1    Wang, C.2    Du, G.3    Zhang, Z.4    Calway, T.5    Yuan, C.6
  • 49
    • 84874569077 scopus 로고    scopus 로고
    • Ginsenosides derived from Asian (Panax ginseng), American ginseng (Panax quinquefolius) and potential cytoactivity
    • Popovich D. G., Yeo C. R., Zhang W., Ginsenosides derived from Asian (Panax ginseng), American ginseng (Panax quinquefolius) and potential cytoactivity. International Journal of Biomedical and Pharmaceutical Sciences 2012 6 1 56 62
    • (2012) International Journal of Biomedical and Pharmaceutical Sciences , vol.6 , Issue.1 , pp. 56-62
    • Popovich, D.G.1    Yeo, C.R.2    Zhang, W.3
  • 50
    • 0035650950 scopus 로고    scopus 로고
    • Brief introduction of Panax ginseng C.A. Meyer
    • supplement 2-s2.0-0035650950
    • Yun T. K., Brief introduction of Panax ginseng C.A. Meyer. Journal of Korean Medical Science 2001 16 supplement S3 S5 2-s2.0-0035650950
    • (2001) Journal of Korean Medical Science , vol.16
    • Yun, T.K.1
  • 51
    • 0035240033 scopus 로고    scopus 로고
    • Panax ginseng - A non-organ-specific cancer preventive?
    • DOI 10.1016/S1470-2045(00)00196-0, PII S1470204500001960
    • Yun T., Panax ginseng-a non-organ-specific cancer preventive? The Lancet Oncology 2001 2 1 49 55 2-s2.0-0035240033 10.1016/S1470-2045(00)00196-0 (Pubitemid 33585917)
    • (2001) Lancet Oncology , vol.2 , Issue.1 , pp. 49-55
    • Yun, T.-K.1
  • 52
    • 0034075605 scopus 로고    scopus 로고
    • The cancer-preventive potential of Panax ginseng: A review of human and experimental evidence
    • DOI 10.1023/A:1008980200583
    • Shin H. R., Kim J. Y., Yun T. K., Morgan G., Vainio H., The cancer-preventive potential of Panax ginseng: a review of human and experimental evidence. Cancer Causes and Control 2000 11 6 565 576 2-s2.0-0034075605 10.1023/A:1008980200583 (Pubitemid 30342846)
    • (2000) Cancer Causes and Control , vol.11 , Issue.6 , pp. 565-576
    • Shin, H.R.1    Kim, J.Y.2    Yun, T.K.3    Morgan, G.4    Vainio, H.5
  • 53
    • 84867685659 scopus 로고    scopus 로고
    • Ginseng, the "immunity boost": The effects of Panax ginseng on immune system
    • Kang S., Min H., Ginseng, the "immunity boost": the effects of Panax ginseng on immune system. Journal of Ginseng Research 2012 36 4 354 368
    • (2012) Journal of Ginseng Research , vol.36 , Issue.4 , pp. 354-368
    • Kang, S.1    Min, H.2
  • 54
    • 79951791059 scopus 로고    scopus 로고
    • Antioxidant activity and ginsenoside pattern of fermented white ginseng
    • 2-s2.0-79951791059 10.5142/jgr.2010.34.3.168
    • Lim S., Cho C., Choi U., Kim Y., Antioxidant activity and ginsenoside pattern of fermented white ginseng. Journal of Ginseng Research 2010 34 3 168 174 2-s2.0-79951791059 10.5142/jgr.2010.34.3.168
    • (2010) Journal of Ginseng Research , vol.34 , Issue.3 , pp. 168-174
    • Lim, S.1    Cho, C.2    Choi, U.3    Kim, Y.4
  • 56
    • 0028260549 scopus 로고
    • Differences in immunomodulating effects between wild and cultured Panax ginseng
    • DOI 10.1006/bbrc.1994.1644
    • Mizuno M., Yamada J., Terai H., Kozukue N., Lee Y. S., Tsuchida H., Differences in immunomodulating effects between wild and cultured Panax ginseng. Biochemical and Biophysical Research Communications 1994 200 3 1672 1678 2-s2.0-0028260549 10.1006/bbrc.1994.1644 (Pubitemid 24181845)
    • (1994) Biochemical and Biophysical Research Communications , vol.200 , Issue.3 , pp. 1672-1678
    • Mizuno, M.1    Yamada, J.2    Terai, H.3    Kozukue, N.4    Lee, Y.S.5    Tsuchida, H.6
  • 57
    • 67349202467 scopus 로고    scopus 로고
    • Total fractionation and characterization of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer
    • 2-s2.0-67349202467 10.1016/j.carbpol.2009.01.034
    • Zhang X., Yu L., Bi H., Li X., Ni W., Han H., Li N., Wang B., Zhou Y., Tai G., Total fractionation and characterization of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer. Carbohydrate Polymers 2009 77 3 544 552 2-s2.0-67349202467 10.1016/j.carbpol.2009.01.034
    • (2009) Carbohydrate Polymers , vol.77 , Issue.3 , pp. 544-552
    • Zhang, X.1    Yu, L.2    Bi, H.3    Li, X.4    Ni, W.5    Han, H.6    Li, N.7    Wang, B.8    Zhou, Y.9    Tai, G.10
  • 58
    • 84888353906 scopus 로고    scopus 로고
    • The inhibitory effects of a rhamnogalacturonan I, (RG-I) domain from ginseng pectin on galectin-3 and its structure-activity relationship
    • Gao X. G., Zhi Y., Sun L., Peng X. X., Zhang T., Xue H. T., Tai G. H., Zhou Y. F., The inhibitory effects of a rhamnogalacturonan I, (RG-I) domain from ginseng pectin on galectin-3 and its structure-activity relationship. The Journal of Biological Chemistry 2013 288 47 33953 33965
    • (2013) The Journal of Biological Chemistry , vol.288 , Issue.47 , pp. 33953-33965
    • Gao, X.G.1    Zhi, Y.2    Sun, L.3    Peng, X.X.4    Zhang, T.5    Xue, H.T.6    Tai, G.H.7    Zhou, Y.F.8
  • 60
    • 84881095428 scopus 로고    scopus 로고
    • A UFLC-MS/MS method with a switching ionization mode for simultaneous quantitation of polygalaxanthone III, four ginsenosides and tumulosic acid in rat plasma: Application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats
    • Lv C., Li Q., Zhang Y., Sui Z., He B., Xu H., Yin Y., Chen X., Bi K., A UFLC-MS/MS method with a switching ionization mode for simultaneous quantitation of polygalaxanthone III, four ginsenosides and tumulosic acid in rat plasma: application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats. Journal of Mass Spectrometry 2013 48 8 904 913
    • (2013) Journal of Mass Spectrometry , vol.48 , Issue.8 , pp. 904-913
    • Lv, C.1    Li, Q.2    Zhang, Y.3    Sui, Z.4    He, B.5    Xu, H.6    Yin, Y.7    Chen, X.8    Bi, K.9
  • 61
    • 2942729844 scopus 로고    scopus 로고
    • Herbal remedies in the United States: Potential adverse interactions with anticancer agents
    • DOI 10.1200/JCO.2004.08.182
    • Sparreboom A., Cox M. C., Acharya M. R., Figg W. D., Herbal remedies in the United States: potential adverse interactions with anticancer agents. Journal of Clinical Oncology 2004 22 12 2489 2503 2-s2.0-2942729844 10.1200/JCO.2004.08.182 (Pubitemid 41115408)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.12 , pp. 2489-2503
    • Sparreboom, A.1    Cox, M.C.2    Acharya, M.R.3    Figg, W.D.4
  • 62
    • 0020407407 scopus 로고
    • The action of ginsenosides extracted from the stems and leaves of Panax ginseng in promoting animal growth
    • 2-s2.0-0020407407
    • Wang B. X., Cui J. C., Liu A. J., The action of ginsenosides extracted from the stems and leaves of Panax ginseng in promoting animal growth. Acta Pharmaceutica Sinica 1982 17 12 899 904 2-s2.0-0020407407
    • (1982) Acta Pharmaceutica Sinica , vol.17 , Issue.12 , pp. 899-904
    • Wang, B.X.1    Cui, J.C.2    Liu, A.J.3
  • 63
    • 4644356962 scopus 로고    scopus 로고
    • Cancer prevention and therapeutics: Panax ginseng
    • Helms S., Cancer prevention and therapeutics: Panax ginseng. Alternative Medicine Review 2004 9 3 259 274 2-s2.0-4644356962 (Pubitemid 39299200)
    • (2004) Alternative Medicine Review , vol.9 , Issue.3 , pp. 259-274
    • Helms, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.