Total fractionation and characterization of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer

Carbohydrate Polymers

Volumn 77, Issue 3, 2009, Pages 544-552

  Zhang, Xu ^a   Yu, Li ^a   Bi, Hongtao ^a   Li, Xianhua ^a   Ni, Weihua ^a   Han, Han ^a   Li, Nan ^a   Wang, Bingqing ^a   Zhou, Yifa ^a   Tai, Guihua ^a  

^a NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

Fractionation; Ginseng polysaccharide; HG; Lymphocyte proliferation; RG I

Indexed keywords

ACIDIC FRACTIONS; ACIDIC POLYSACCHARIDES; ANALYTICAL RESULTS; ARABINOGALACTAN; ETHANOL PRECIPITATIONS; GALACTURONIC ACIDS; GINSENG POLYSACCHARIDE; HG; HIGH PERFORMANCE GEL PERMEATION CHROMATOGRAPHIES; HOMOGALACTURONAN; LYMPHOCYTE PROLIFERATION; NEUTRAL FRACTIONS; NEUTRAL SUGARS; PANAX GINSENGS; RG-I; RHAMNOGALACTURONAN; T CELLS; WATER-SOLUBLE POLYSACCHARIDES;

BIOPOLYMERS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ESTERS; ETHANOL; GELATION; GELS; ION EXCHANGE; RANGE FINDING; STARCH; SUGAR (SUCROSE); SUGARS;

POLYSACCHARIDES;

PANAX GINSENG;

EID: 67349202467     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2009.01.034     Document Type: Article

References (36)

1. Blumenkrantz N., and Asboe-Hansen G. New method for quantitative determination of uronic acids. Analytical Biochemistry 54 (1973) 484-489
2. Catoire L., Goldberg R., Pierron M., Morvan C., and Hervé Du Penhoat C. An efficient procedure for studying pectin structure which combines limited depolymerization and C-13 NMR. European Biophysics Journal 27 (1998) 127-136
3. Duan J., Wang X., Dong Q., Fang J., and Li X. Structural features of a pectic arabinogalactan with immunological activity from the leaves of Diospyros kaki. Carbohydrate Research 338 (2003) 1291-1297
4. Dubois M., Gilles K.A., Hamilton J.K., Rebers P.A., and Smith F. Colorimetric method for determination of sugars and related substances. Analytical Chemistry 28 (1956) 350-356
5. Fu P., Gao Q., Wang W., Jiang R., Zhong C., Jiao L., et al. Chemical properties and anti-tumoractivity of polysaccharides from roots of Panax ginseng. Journal of Norman Bethune University of Medical Science 20 (1994) 439-441
6. Gane A.M., Craik D., Munro S.L.A., Howlett G.J., Clarke A.E., and Bacic A. Structural analysis of the carbohydrate moiety of arabinogalactan-proteins from stigmas and styles of nicotiana alata. Carbohydrate Research 277 (1995) 67-85
7. Han S.B., Kim Y.H., Lee C.W., Park S.M., Lee H.Y., Ahn K.S., et al. Characteristic immunostimulation by angelan isolated from Angelica gigas Nakai. Immunopharmacology 40 (1998) 39-48
8. Inngjerdingen K.T., Patel T.R., Chen X., Kenne L., Allen S., Morris G.A., et al. Immunological and structural properties of a pectic polymer from Glinus oppositifolius. Glycobiology 17 (2007) 1299-1310
9. Lee J.H., Shim J.S., Lee J.S., Kim M.K., Chung M.S., and Kim K.H. Pectin-like acidic polysaccharide from Panax ginseng with selective antiadhesive activity against pathogenic bacteria. Carbohydrate Research 341 (2006) 1154-1163
10. Lin Z.-B. Cellular and molecular mechanisms of immuno-modulation by ganoderma lucidum. Journal of Pharmacological Sciences 99 2 (2005) 144-153
11. Luo D., and Fang B. Structural identification of ginseng polysaccharides and testing of their antioxidant activities. Carbohydrate Polymers 72 (2008) 376-381
12. McNeil M., Darvill A.G., and Albersheim P. Structure of plant cell walls. X. Rhamnogalacturonan I, a structurally complex pectic polysaccharide in the walls of suspension-cultured sycamore cells. Plant Physiology 66 (1980) 1128-1134
13. Nergard C.S., Kiyohara H., Reynolds J.C., Thomas-Oates J.E., Matsumoto T., Yamada H., et al. Structures and structure-activity relationships of three mitogenic and complement fixing pectic arabinogalactans from the malian antiulcer plants Cochlospermum tinctorium A. Rich and Vernonia kotschyana Sch. Bip. ex Walp. Biomacromolecules 7 (2006) 71-79
14. Oshima Y., Konno C., and Hikino H. Isolation and hypoglycemic activity of Panaxans I, J, K and L, glycans of Panax ginseng roots. Journal of Ethnopharmacology 14 (1985) 255-259
15. Ovodov Y.S., and Solov'eva T.F. Polysaccharides of Panax ginseng. Khimiya Prirodnykh Soedinenii 2 (1966) 299-303
16. Paulsen B.S., and Barsett H. Bioactive pectic polysaccharides. Advances in Polymer Science 186 (2005) 69-101
17. Pérez S., Rodríguez-Carvajal M.A., and Doco T. A complex plant cell wall polysaccharide: Rhamnogalacturonan II. A structure in quest of a function. Biochimie 85 (2003) 109-121
18. Polle A.Y., Ovodova R.G., Shashkov A.S., and Ovodov Y.S. Some structural features of pectic polysaccharide from tansy, Tanacetum vulgare L. Carbohydrate Polymers 49 (2002) 337-344
19. Schols H.A., and Voragen A.G.J. Complex pectins: Structure elucidation using enzymes. In: Visser J., and Voragen A.G.J. (Eds). Pectins and pectinases (1996), Elsevier Science BV, Amsterdam 3-19
20. Sedmark J.J., and Grossberg S.E. A rapid, sensitive, and versatile assay for protein using Coomassie brilliant blue G250. Analytical Biochemistry 79 (1979) 544-552
21. Sevag M.G., Lackman D.B., and Smolens J. The isolation of the components of streptococcal nucleoproteins in serologically active form. Journal of Biological Chemistry 124 (1938) 425-436
22. Shin M.J., Kim Y.S., Kwak Y.S., Song Y.B., Kim Y.S., and Park J.D. Enhancement of antitumor effects of paclitaxel (taxol) in combination with red ginseng acidic polysaccharide (RGAP). Planta Medica 70 (2004) 1033-1038
23. Solov'eva T.F., Arsenyuk L.V., and Ovodov Y.S. Some structural features of Panax ginseng C. A. Mey pectin. Carbohydrate Research 10 (1969) 13-18
24. Song J.Y., Han S.K., Son E.H., Pyo S.N., Yun Y.S., and Yi S.Y. Induction of secretory and tumoricidal activities in peritoneal macrophages by ginsan. International Immunopharmacology 2 (2002) 857-865
25. Suzuki Y., and Hikino H. Mechanisms of hypoglycemic activity of Panaxans A and B, glycans of Panax ginseng roots: Effects on the key enzymes of glucose metabolism in the liver of mice. Phototherapy Research 3 (1989) 15-19
26. Thibault J., Renard C.M.G.C., Axelos M.A.V., Roger P., and Crepeau M. Studies of the length of homogalacturonic regions in pectins by acid hydrolysis. Carbohydrate Research 238 (1993) 271-286
27. Tomoda M., Hirabayashi K., Shimizu N., Gonda R., and Ohara N. The core structure of ginseng PA, a phagocytosis-activation polysaccharide from the root of Panax ginseng. Biological and Pharmaceutical Bulletin 17 (1994) 1287-1291
28. Tomoda M., Hirabayashi K., Shimizu N., Gonda R., Ohara N., and Takada K. Characterization of two novel polysaccharides having immunological activities from the root of Panax ginseng. Biological and Pharmaceutical Bulletin 16 (1993) 1087-1090
29. Tomoda M., Shimada K., Konno C., and Hikino H. Structure of Panaxan B. A hypoglycaemic glycan of Panax ginseng roots. Phytochemistry 24 (1985) 2431-2433
30. Tomoda M., Shimada K., Konno C., Sugiyama K., and Hikino H. Partial structure of Panaxan A, a hypoglycaemic glycan of Panax ginseng roots. Planta Medica 50 (1984) 436-438
31. Tomoda M., Takeda K., Shimizu N., Gonda R., Ohara N., Takada K., et al. Characterization of two acidic polysaccharides having immunological activities from the root of Panax ginseng. Biological and Pharmaceutical Bulletin 16 (1993) 22-25
32. Vidal S., Williams P., Doco T., Moutounet M., and Pellerin P. The polysaccharides of red wine: Total fractionation and characterization. Carbohydrate Polymers 54 (2003) 439-447
33. Wang X.S., Liu L., and Fang J.N. Immunological activities and structure of pectin from centella asiatica. Carbohydrate Polymers 60 (2005) 95-101
34. Yang X., Zhao Y., Wang Q., Wang H., and Mei Q. Analysis of the monosaccharide components in Angelica polysaccharides by high performance liquid chromatography. Analytical Science 21 (2005) 1177-1180
35. Yapo B.M., Lerouge P., Thibault J., and Ralet M. Pectins from citrus peel cell walls contain homogalacturonans homogenous with respect to molar mass, rhamnogalacturonan I and rhamnogalacturonan II. Carbohydrate Polymers 69 (2007) 426-435
36. Zheng Y., Wang X.-S., and Fang J. Two acidic polysaccharides from the flowers of Chrysanthemum morifolium. Journal of Asian Natural Products Research 8 (2006) 217-222